Sunday, December 8, 2002 - including Plenary Sessions

OncoLink attended the 44th Annual Meeting of the American Society of Hematology (ASH) from Philadelphia, Pennsylvania. OncoLink reporters provided in-depth, up-to-the-minute coverage of sessions and presentations.

ASH Attendees at the Pennsylvania Convention Center

Characterization of the Genomic Breakpoint in t(11:18)(q21:q21) of MALT Lymphoma Presenter: Hongxiang LiuPresenter's Affiliation: University College LondonType of Session: ScientificBackground The t(11:18)(q21:q21) is the most frequent chromosomal aberration found in mucosa associated lymphoid tissue (MALT) lymphoma. This...
Double Autologous Transplantation Improves Survival of Multiple Myeloma Patients: Final Analysis of a Prospective Randomized Study of the "Intergroupe Francophone du Myelome" (IFM-94). Presenter: Michel AttalPresenter's Affiliation: Hopital Purpan; Toulouse, FranceType of Session: PlenaryBackground Multiple Myeloma has been a challenging disease with little change in the Median Survival (MS) in the past 20 years; MS averages 30-36...
High Incidence of t(11:18)(q21:q21) in Helicobacter pylori Negative Gastric MALT Lymphoma Presenter: Hongtao YePresenter's Affiliation: University College LondonType of Session: ScientificBackground Gastric mucosa associated lymphoid tissue (MALT) lymphoma is strongly associated with H. pylori infection. Only approximately 10% of cases...
Histological and Clinical Prognostic Factors in Follicular Lymphoma: Proposal for a Prognostic Model Presenter: Irit AviviPresenter's Affiliation: University College London; UKType of Session: ScientificBackground Follicular lymphoma (FL) is one of the most common types of non-Hodgkin's lymphoma. Despite this, prognostic models to predict patient's...
Imatinib (STI571, Gleevac) as Initial Therapy for Patients with Newly Diagnosed Ph + Chronic Myeloid Leukemia (CML): Results of a Randomized Phase III Study vs Interferon-Alpha + Cytarabine (IFN + AraC) Presenter: Richard A. LarsonPresenter's Affiliation: International Randomized IFN vs. STI571 Study GroupType of Session: PlenaryBackground Imatinib is a specific inhibitor of the BCR-ABL tyrosine kinase, which is the oncogene classically associated...
Isolated Central Nervous System (ICNS) Relapse in Children With Standard Risk (SR) ALL: Results of CCG-1952. Presenter: Susan LindemulderPresenter's Affiliation: University of Colorado Health Sciences CenterType of Session: ScientificBackground The CCG 1952 trial was designed to assess event free survival and ICNS failure in standard risk ALL patients...
Long term follow up of an Alemtuzumab (CAMPATH-1H) containing reduced intensity Allogeneic Transplant Regimen for Non-Hodgkins Lymphoma (NHL) Presenter: Emma MorrisPresenter's Affiliation: UK Collaborative Group, United KingdomType of Session: ScientificBackground Campath is an antibody that targets CD 52 which is a T cell marker. Campath has been studied in induction therapies for...
Peptide Vaccination with PR1 Elicits Active T Cell Immunity That Induces Cytogenetic Remission in Acute Myelogenous Leukemia. Presenter: Jeffrey J. MolldremPresenter's Affiliation: M.D. AndersonType of Session: PlenaryBackground Despite decades of research there are no FDA approved cancer vaccines. The concept of tumor immunosurveillance has recently become repopularized...
Primary Pulmonary MALT Lymphomas Show Frequent and Heterogenous Cytogenetic Abnormalities, Including a Previously Unreported MALT1-IGH Translocation Presenter: Ellen D. RemsteinPresenter's Affiliation: Mayo Clinic; Rochester, MNType of Session: ScientificBackground Mucosa-associated lymphoid tissue (MALT) lymphoma is a low-grade B-cell malignant lymphoma that arises in diverse extranodal sites. ...
Results of Myeloablative Allogenic Stem Cell Transplant (SCT) for Severe Sickle Cell Disease in France Presenter: Francoise BernaudinPresenter's Affiliation: SFGM-TC, FranceType of Session: PlenaryBackground Sickle cell disease effects the black population and is responsible for many hospitalizations and a high consumption of red blood cell...
Separation of Blood and Lymphatic Vascular Networks Is Regulated by the Hematopoietic Signaling Proteins SLP-76 and Syk. Presenter: Farhad AbtahianPresenter's Affiliation: University of PennsylvaniaType of Session: PlenaryBackground Currently we do not know how blood vessels and lymph vessles form in the fetus. We do know that they begin their development together...
Thioguanine-Related Veno-Occlusive Disease (VOD) of the Liver in Children with Acute Lymphoblastic Leukemia (ALL): Report from United Kingdom Medical Research Council (UK MRC) Trial ALL97 Presenter: Ajay J. VoraPresenter's Affiliation: Children's Hospital, SheffieldType of Session: ScientificBackground MRC ALL97 randomized non-B ALL patients aged 1-18 to thioguanine (TG) and dexamethasone or mercaptopurine (MP) and prednisolone. ...