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Abramson Cancer CenterSaturday, December 7, 2002
 OncoLink attended the 44th Annual Meeting of the American Society of Hematology (ASH) from Philadelphia, Pennsylvania. OncoLink reporters provided in-depth, up-to-the-minute coverage of sessions and presentations. |
 Historic Reading Terminal Market Pennsylvania Convention Center |
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Bexxar Radioimmunotherapy Produces a Substantial Number of Durable Complete Responses in Patients with Multiply Relapsed or Refractory Low Grade or Transformed Low Grade Non-Hodgkin's Lymphoma
Presenter: Mark S. KaminskiPresenter's Affiliation: University of MichiganType of Session: PosterBackground Virtually all patients with low Grade Non-Hodgkin's Lymphoma (LG NHL) relapse. Relapsed or refractory LG NHL is very difficult to treat, as... |
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Duration of Molecular Remission in Patients with Acute Promyelocytic Leukemia (APML) Treated Primarily with Arsenic Tri-oxide
Presenter: B GeorgPresenter's Affiliation: Christian Medical College; Vellore, IndiaType of Session: PosterBackground Arsenic trioxide (As2O3) has been shown to be very effective for the treatment of APML. Most data has been with relapsed disease.... |
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High Response Rates and Durable Remissions in Patients with Previously Untreated Advanced-Stage Follicular Lymphoma Treated with Tositumomab and Iodine I-131 Tositumomab (Bexxar)
Presenter: Mark S. KaminskiPresenter's Affiliation: University of MichiganType of Session: PosterBackground I-131 Tositumomab is a monoclonal murine antibody directed against the CD20 cell surface protein present on most lymphocytes, including most... |
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Intermediate Dose Melphalan for de novo Multiple Myeloma gives high complete response rate and durable long term survival
Presenter: Mathew StreetlyPresenter's Affiliation: Queen Elizabeth Hospital, Woolwich, UKType of Session: PosterBackground Multiple Myeloma remains a disease with extremely high recurrence rates even after agressive chemotherapy. Oral Melphalan has... |
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Long Term Follow Up of a Phase II study of Rituximab in Combination with CHOP Chemotherapy in Patients with Previously Untreated Aggressive Non-Hodgkins Lymphoma (NHL)
Presenter: J.M. VosePresenter's Affiliation: University of Nebraska Medical CenterType of Session: PosterBackground Standard therapy for NHL is combination chemotherapy with CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) Rituxan, a... |
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Oral Fludarabine phosphate as first-line treatment of chronic lymphocytic leukemia
Presenter: Jean-Francois RossiPresenter's Affiliation: CHU; Montpellier, FranceType of Session: PosterBackground Fludarabine phosphate is a nucleotide analog of arabinoside which has achieved overall response rates (ORR) of 63-70% in previously... |
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Phase I-II study of Genasense (Bcl-2 Antisense Oligonucleotide) in Patients With Advanced Chronic Lymphocytic Leukemia
Presenter: Kanti R. RaiPresenter's Affiliation: Long Island Jewish Medical CenterType of Session: PosterBackground Chronic Lymphocytic Leukemia (CLL) is the most common chronic leukemia in adults. It's course is usually slow and insiduous however... |
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Preliminary Report of a Phase II Study of the Safety and Efficacy of Gemtuzumab Ozogamicin (Mylotarag)Given in Combination with Cytarabine in Patients with Acute Myelogenous Leukemia
Presenter: Michele BaccaraniPresenter's Affiliation: Ospedale S. Orsola; Bologna, ItalyType of Session: PosterBackground Gemtuzumab has been approved in the United States for the treatment of patients aged sixty and above with CD33+ AML in first... |
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Prevalence and Management of Anemia in Patients with Hematologic Malignancies and Solid Tumors: Results from the European Cancer Anemia Survey (ECAS)
Presenter: Heinz LudwigPresenter's Affiliation: ECAS Advisory BoardType of Session: PosterBackground Anemia (hgb Large randomized trials show that correction of anemia leads to symptom improvement and improved quality of life (QOL). ... |
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Quality of Life, Blood Transfusions, and Toxicity, in Anemic Patients with Advanced Cancer Receiving Weekly Erythropoietin While on Chemotherapy: Results from a Phase III Randomized Double-Blind Placebo-Controlled Study.
Presenter: Jeff A. SloanPresenter's Affiliation: Mayo ClinicType of Session: PosterBackground Anemia is obviously a large problem in the population of patients who are receiving chemotherapy. This anemia is likely amplified in those patients with... |
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Rituximab Treatment Failures: Tositumomab and Iodine I-131 Tositumomab (Bexxar) Can Produce Meaningful Durable Responses
Presenter: Sandra J. HorningPresenter's Affiliation: Stanford UniversityType of Session: PosterBackground Rituxan is a chimeric monoclonal antibody (MAb)directed against the CD20 cell surface protein. It effected a 50% overall response rate in the... |
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Zevalin Radioimmunotherapy is Not Associated with an Increased Incidence of Secondary Myelodysplastic Syndrome (MDS) or Acute Myelogenous Leukemia (AML)
Presenter: M.S. CzuczmanPresenter's Affiliation: Roswell Park Cancer InstituteType of Session: PosterBackground Zevalin is an anti-CD 20 monoclonal antibody with bonded Yttrium-90, making it a radioimmunotherapy. It is being used more commonly in... |
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