Tuesday, October 18, 2005, including Mini-Plenary Sessions

OncoLink coverage of the Annual Meeting of the American Society for Therapeutic Radiology And Oncology, ASTRO, October 16-20, 2005, held in Denver, Colorado. OncoLink reporters provide in-depth, up-to-the-minute coverage of sessions and presentations.

The Denver Convention Center

A Phase I Clinical Trial Assessing Temozolamide and Tamoxifen with Concomitant Radiotherapy for the Treatment of High-Grade Gliomas Presenter: T.W. FlanneryPresenter's Affiliation: Radiation Oncology, University of Maryland, Baltimore, MDType of Session: ScientificBackground One of the many recent advances in the management of high grade gliomas includes the slight survival...
Adaptive Planning and Delivery to Account for Anatomical Changes Induced by Radiation Therapy of Head and Neck Cancer Presenter: M.B. SharpePresenter's Affiliation: Princess Margaret Hospital, Toronto, ONType of Session: PlenaryBackground Radiation-induced changes manifested during treatment can theoretically increase the risk of local failure and alter predicted...
ASTRO Patient Summary: A Phase I Clinical Trial Assessing Temozolamide and Tamoxifen with Concomitant Radiotherapy for the Treatment of High-Grade Gliomas A Phase I Clinical Trial Assessing Temozolamide and Tamoxifen with Concomitant Radiotherapy for the Treatment of High-Grade Gliomas There are limited therapies available for patients with high-grade gliomas. One particular problem is finding...
ASTRO Patient Summary: Concurrent Trastuzumab and Radiation Therapy (RT) in the Adjuvant Treatment of Breast Cancer Concurrent Trastuzumab and Radiation Therapy (RT) in the Adjuvant Treatment of Breast Cancer Patients with Her2/neu positive breast cancer are considered to have higher risk disease, but have an additional therapy option in trastuzumab (Herceptin)....
ASTRO Patient Summary: Long-Term Outcomes of RTOG 90-03: A Comparison of Hyperfractionation and Two Variants of Accelerated Fractionation to Standard Fractionation Radiotherapy for Head and Neck Squamous Cell Carcinoma Long-Term Outcomes of RTOG 90-03: A Comparison of Hyperfractionation and Two Variants of Accelerated Fractionation to Standard Fractionation Radiotherapy for Head and Neck Squamous Cell Carcinoma Traditionally, radiation has been administered once a...
ASTRO Patient Summary: Long-Term Results of a Prospective Trial of Mantle Irradiation (RT) Alone for Early-Stage Hodgkin's Disease (HD) Long-Term Results of a Prospective Trial of Mantle Irradiation (RT) Alone for Early-Stage Hodgkin's Disease (HD) Historically, patients with early stage Hodgkin's Disease were treated with radiation therapy alone. More recently, chemotherapy has...
ASTRO Patient Summary: Objective Versus Subjective Assessment of Single Photon Emission Computed Tomography (SPECT) Cardiac Perfusion Scans to Assess for Radiation Therapy (RT) Induced Cardiac Injury Objective Versus Subjective Assessment of Single Photon Emission Computed Tomography (SPECT) Cardiac Perfusion Scans to Assess for Radiation Therapy (RT) Induced Cardiac Injury It has long been known that women who receive radiation to the left...
ASTRO Patient Summary: Radiation is an Important Component of Therapy for Patients with Stage III Breast Cancer Who Achieve a Pathological Complete Response after Neoadjuvant Chemotherapy Radiation is an Important Component of Therapy for Patients with Stage III Breast Cancer Who Achieve a Pathological Complete Response after Neoadjuvant Chemotherapy Patients who present with locally advanced breast cancer (spread to local lymph...
ASTRO Patient Summary: The Influence of Intrafraction Movement on Margins for Prostate Radiotherapy The Influence of Intrafraction Movement on Margins for Prostate Radiotherapy When a patient is set up for radiation treatment, the physician applies pinpoint skin marks called "tattoos" to guide the x-ray beams each day and to assure that the...
Concurrent Trastuzumab and Radiation Therapy (RT) in the Adjuvant Treatment of Breast Cancer Presenter: J. R. BellonPresenter's Affiliation: Dana-Farber Cancer InstituteType of Session: ScientificBackground Her-2-Neu is overexpressed in approximately 25% of breast cancer patients and confers a worse prognosis. Adjuvant trastuzumab improves...
Dose-Dependent Effects of Radiation Therapy on Cerebral Blood Flow, Metabolism and Neurocognitive Dysfunction Presenter: C.A. HahnPresenter's Affiliation: Radiation Oncology, Duke University Medical Center, Durham, NCType of Session: ScientificBackground Radiation therapy can cause neurocognitive dysfunction in patients treated for brain tumors. ...
Dosimetric Correlation of Acute and Late Xerostomia with Patients Treated with IMRT and Chemotherapy Presenter: A.K. BhatnagarPresenter's Affiliation: Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PAType of Session: ScientificBackground One of the greatest determinants of quality of life following radiation for head and...
Lobular Carcinoma in Situ (LCIS) in Association with Invasive Breast Cancer: Does LCIS Predict for Local Recurrence? Presenter: S. JollyPresenter's Affiliation: Radiation Oncology, William Beaumont Hospital, Royal Oak, MI, Pathology, William Beaumont Hospital, Royal Oak, MIType of Session: ScientificBackground More than 5% of malignant breast cancers have a...
Long-Term Outcomes of RTOG 90-03: A Comparison of Hyperfractionation and Two Variants of Accelerated Fractionation to Standard Fractionation Radiotherapy for Head and Neck Squamous Cell Carcinoma Presenter: A. TrottiPresenter's Affiliation: Moffitt Cancer Center at Univ. South Florida, Tampa, FLType of Session: ScientificBackground In the late 1980's, a variety of radiation dose fractionation schedules were in use at different...
Long-Term Results of a Prospective Trial of Mantle Irradiation (RT) Alone for Early-Stage Hodgkin's Disease (HD) Presenter: Andrea NgPresenter's Affiliation: Brigham and Women's Hospital, Boston, MAType of Session: ScientificBackground The historical approach to the management of early stage Hodgkin's disease was radiation alone. Recently, the...
Objective Versus Subjective Assessment of Single Photon Emission Computed Tomography (SPECT) Cardiac Perfusion Scans to Assess for Radiation Therapy (RT) Induced Cardiac Injury Presenter: Robert G. Prosnitz, MDPresenter's Affiliation: Duke University Medical Center, Durham, NCType of Session: PlenaryBackground Radiation therapy has been used in the treatment of breast cancer for many years. Multiple clinical...
Radiation is an Important Component of Therapy for Patients with Stage III Breast Cancer Who Achieve a Pathological Complete Response after Neoadjuvant Chemotherapy Presenter: SE McGuirePresenter's Affiliation: Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TXType of Session: ScientificBackground Neoadjuvant chemotherapy is the standard for locally advanced breast cancer and for...
The Association Between the Mean Heart Dose, Mean Lung Dose, Tumor Location and RT-associated Heart and Lung Toxicity Presenter: L.B. MarksPresenter's Affiliation: Radiation Oncology, Duke University Medical Center, Durham, NCType of Session: ScientificBackground One of the side effects of lung irradiation is radiation pneumonitis, which can be manifested as...
The Influence of Intrafraction Movement on Margins for Prostate Radiotherapy Presenter: D. W. LitzenbergPresenter's Affiliation: University of MichiganType of Session: PlenaryBackground As set-up and interfraction errors are being reduced by in-room imaging guidance, the importance of intrafraction errors increases....
Volume of Abnormal Tumor Tissue on FDG-PET -A Predictor of Progression-free Survival in Hodgkin's Lymphoma? Presenter: Martin HutchingsPresenter's Affiliation: Copenhagen University Hosptial, Copenhagen, DenmarkType of Session: ScientificBackground Pre-treatment tumor volume is a well characterized independent risk factor for developing tumor...