Patient Summaries

Our nurse educator explains the science behind the news highlights from this year's ASTRO 2007 meeting.

A Phase II Study of a Paclitaxel Based Chemoradiation Regimen With Selective Surgical Salvage for Resectable Locoregionally Advanced Esophageal Cancer: Initial Reporting of RTOG 0246 Scientific Session: A Phase II Study of a Paclitaxel Based Chemoradiation Regimen With Selective Surgical Salvage for Resectable Locoregionally Advanced Esophageal Cancer: Initial Reporting of RTOG 0246 Prior studies (RTOG 8501) have demonstrated...
A Phase II Trial of Conformal Radiation Therapy for Pediatric Low-Grade Glioma: 5-year Disease Control and Functional Outcomes Scientific Session: A Phase II Trial of Conformal Radiation Therapy for Pediatric Low-Grade Glioma: 5-year Disease Control and Functional Outcomes Low-grade gliomas in children are treated with radiation therapy in combination with chemotherapy...
A Phase III Trial to Compare Standard Versus Accelerated Fractionation in Combination With Concurrent Cisplatin for Head and Neck Carcinomas (RTOG 0129): Report of Compliance and Toxicity Scientific Session: A Phase III Trial to Compare Standard Versus Accelerated Fractionation in Combination With Concurrent Cisplatin for Head and Neck Carcinomas (RTOG 0129): Report of Compliance and Toxicity This study looked at the use of standard...
Breast Cancer After Supradiaphragmatic Irradiation for Hodgkin's Disease; Risk Analysis and Possible Surveillance Strategies Scientific Session: Breast Cancer After Supradiaphragmatic Irradiation for Hodgkin's Disease; Risk Analysis and Possible Surveillance Strategies Hodgkin’s disease is one of the first cancers that was found to be curable with radiation...
Breast Magnetic Resonance Imaging in the Management of Early Breast Cancer: Implications for Partial Breast Irradiation Scientific Session: Breast Magnetic Resonance Imaging in the Management of Early Breast Cancer: Implications for Partial Breast Irradiation Two oncology research groups (NSABP & RTOG) are conducting a study of accelerated partial breast...
Can Adjuvant Neck Dissection be Deferred in Locally Advanced Head and Neck Cancer Patients with Complete Response to Definitive Chemoradiotherapy? Scientific Session: Can Adjuvant Neck Dissection be Deferred in Locally Advanced Head and Neck Cancer Patients wtih Complete Response to Definitive Chemoradiotherapy? Patients with locally advanced squamous cell cancer of the head and neck are...
Chest Wall Radiation Alone for Breast Cancer Patients With 1-3 Positive Lymph Nodes Treated by Mastectomy Scientific Session: Chest Wall Radiation Alone for Breast Cancer Patients With 1-3 Positive Lymph Nodes Treated by Mastectomy It is currently known that post-mastectomy radiation to the chest wall and axillary/clavicular lymphatics reduces local...
Comparison of Health Related Quality of Life (HRQOL) in Men Treated With Radical Prostatectomy or External Beam Radiotherapy for Localized Prostate Cancer Scientific Session: Comparison of Health Related Quality of Life (HRQOL) in Men Treated With Radical Prostatectomy or External Beam Radiotherapy for Localized Prostate Cancer Although no large, randomized trials have directly compared outcomes...
Definitive Results of the French FFCE-SFRO 2000-01 Study: Phase III Trial Comparing Chemoradiotherapy (Cisplatin and Infusional 5-FU) Followed by Gemcitabine vs. Gemcitabine Alone in Patients with Locally Advanced Non Metastatic Pancreatic Cancer Scientific Session: Definitive Results of the French FFCE-SFRO 2000-01 Study: Phase III Trial Comparing Chemoradiotherapy (Cisplating and Infusional 5-FU) Followed by Gemcitabine vs. Gemcitabine Alone in Patients with Locally Advanced Non Metastatic...
Dose to the Larynx Predicts for Swallowing Complications Following IMRT and Chemotherapy Scientific Session: Dose to the Larynx Predicts for Swallowing Complications Following IMRT and Chemotherapy The combination of chemotherapy and radiation therapy has improved survival for people with head and neck cancers, but this has led to an...
Impact of Postoperative Radiation Therapy on Postmastectomy Breast Reconstruction Scientific Session: Impact of Postoperative Radiation Therapy on Postmastectomy Breast Reconstruction Many women are now offered immediate reconstruction after mastectomy, which in many cases is followed by radiation therapy. Reconstructions are...
Is Long-Term Survival in Glioblastoma Possible? Updated Results of the EORTC/NCIC Phase III Randomized Trial on Radiotherapy (RT) and Concomitant and Adjuvant Temozolomide (TMZ) versus RT Alone Scientific Session: Is Long-Term Survival in Glioblastoma Possible? Updated Results of the EORTC/NCIC Phase III Randomized Trial on Radiotherapy (RT) and Concomitant and Adjuvant Temozolomide (TMZ) versus RT Alone Stupp et al. (New England Journal...
Neurocognitive Impact of Whole Brain Radiation on Patients With Brain Metastases: Secondary Analysis of RTOG BR-0018 Scientific Session: Neurocognitive Impact of Whole Brain Radiation on Patients With Brain Metastases: Secondary Analysis of RTOG BR-0018 This is the second report from a study on the ability to evaluate neurocognitive functioning after whole brain...
Outcome After Stereotactic Radiotherapy in 'High-Risk' Patients With Stage I Non-small Cell Lung Cancer (NSCLC) Scientific Session: Outcome After Stereotactic Radiotherapy in 'High-Risk' Patients With Stage I Non-small Cell Lung Cancer (NSCLC) Stage I non-small cell lung cancer is optimally treated with surgery, but some patients may not be candidates for...
Percent Necrosis in Extremity Soft Tissue Sarcoma After Preoperative Radiation Alone Versus Preoperative Radiation and Chemotherapy Scientific Session: Percent Necrosis in Extremity Soft Tissue Sarcoma After Preoperative Radiation Alone Versus Preoperative Radiation and Chemotherapy Studies of soft tissue sarcomas from UCLA suggested that in soft tissue sarcomas of the...
Phase II Randomized Trial of Surgery Followed by Chemoradiation Plus Cetuximab for High-Risk Squamous Cell Carcinoma of the Head and Neck (RTOG 0234) Scientific Session: Phase II Randomized Trial of Surgery Followed by Chemoradiation Plus Cetuximab for High-Risk Squamous Cell Carcinoma of the Head and Neck (RTOG 0234) It is known that post-operative concurrent chemotherapy and radiation improves...
Post-resectional CA 19-9 Values >90 are Associated With Significantly Worse Survival in Patients With Pancreatic Carcinoma Treated With Adjuvant Therapy on RTOG 9704 - Implications for Current and Future Trials Scientific Session: Post-resectional CA 19-9 Values >90 are Associated With Significantly Worse Survival in Patients With Pancreatic Carcinoma Treated With Adjuvant Therapy on RTOG 9704 - Implications for Current and Future Trials Previous...
Prophylactic Cranial Irradiation (PCI) in Extensive Stage Small Cell Lung Cancer (ES-SCLC) (EORTC 22993-08993) Scientific Session: Prophylactic Cranial Irradiation (PCI) in Extensive Stage Small Cell Lung Cancer (ES-SCLC) (EORTC 22993-08993) Small cell lung cancer is known to spread (metastasize) to the brain. Two years after diagnosis, 50% of patients will...
Statin Use and Clinical Outcomes after High-Dose Radiotherapy for Prostate Cancer Scientific Session: Statin Use and Clinical Outcomes after High-Dose Radiotherapy for Prostate Cancer In laboratory studies, statin drugs have shown some anti-cancer activity. This study looked at the use of statin therapy during radiation...
The Impact of Boost Dose and Margins on the Local Recurrence Rate in Breast Conserving Therapy: Results From the EORTC Boost-No Boost Trial Scientific Session: The Impact of Boost Dose and Margins on the Local Recurrence Rate in Breast Conserving Therapy: Results From the EORTC Boost-No Boost Trial Breast conserving therapy (BCT) consists of a breast conserving surgery (i.e. a...
Toxicity Analysis of RTOG 0236 Using Stereotactic Body Radiotherapy to Treat Medically Inoperable Early Stage Lung Cancer Patients Scientific Session: Toxicity Analysis of RTOG 0236 Using Stereotactic Body Radiotherapy to Treat Medically Inoperable Early Stage Lung Cancer Patients Stage I non-small cell lung cancer is optimally treated with surgery, but some patients may not...
Update of the Results of the Dutch Multicenter Dose Escalation Trial of Radiotherapy for Localized Prostate Cancer Scientific Session: Update of the Results of the Dutch Multicenter Dose Escalation Trial of Radiotherapy for Localized Prostate Cancer Improved radiation techniques (IMRT and 3D conformal radiation therapy) have allowed for higher doses of...

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