OncoLink Cancer Treatment and Resources

Monday, October 29 2007

Includes the plenary sessions and scientific highlights from the head and neck, pancreatic, and lung cancer sessions as well as patient friendly summaries of key presentations.

A Phase III Trial to Compare Standard Versus Accelerated Fractionation in Combination With Concurrent Cisplatin for Head and Neck Carcinomas (RTOG 0129): Report of Compliance and Toxicity
Presenter: Kian Ang, MD, PhDPresenter's Affiliation: MD Anderson Cancer CenterType of Session: ScientificBackground The definitive treatment of locally advanced head and neck cancer with radiation has evolved greatly over the past 15...
A Small Molecular Inhibitor of TGFß Protects Against the Development of Radiation Induced Lung Injury
Presenter: Mitchell S. Anscher, MDPresenter's Affiliation: Virginia Commonwealth University Medical Center, Richmond, VAType of Session: PlenaryBackground One of the primary limitations that inhibits dose escalation in the treatment of lung...
Can Adjuvant Neck Dissection be Deferred in Locally Advanced Head and Neck Cancer Patients wtih Complete Response to Definitive Chemoradiotherapy?
Presenter: S. YovinoPresenter's Affiliation: University of Maryland Medical System, Baltimore, MDType of Session: ScientificBackground With recent advances in radiotherapy techniques and their use with concurrent chemotherapy, patients with...
Characterization of Pancreatic Tumor Motion Using 4D MRI: Surrogates for Tumor Position Should be Used With Caution
Presenter: Mary Feng, MDPresenter's Affiliation: University of Michigan Medical CenterType of Session: PlenaryBackground Pancreatic cancer is associated with poor outcomes and limited long-term survival, and there are numerous challenges that...
Is Long-Term Survival in Glioblastoma Possible? Updated Results of the EORTC/NCIC Phase III Randomized Trial on Radiotherapy (RT) and Concomitant and Adjuvant Temozolomide (TMZ) versus RT Alone
Presenter: Rene-Olivier Mirimanoff , MDPresenter's Affiliation: University Hospital Lausanne, Lausanne, SwitzerlandType of Session: PlenaryBackground Glioblastoma Multiforme (GBM) is a devastating malignancy with poor survival even with full...
Phase II Randomized Trial of Surgery Followed by Chemoradiation Plus Cetuximab for High-Risk Squamous Cell Carcinoma of the Head and Neck (RTOG 0234)
Presenter: Paul Harari, MDPresenter's Affiliation: University of WisconsinType of Session: ScientificBackground Prior studies have demonstrated an improvement in local control and overall survival in post operative, high risk patients with...
Post-resectional CA 19-9 Values >90 are Associated With Significantly Worse Survival in Patients With Pancreatic Carcinoma Treated With Adjuvant Therapy on RTOG 9704 - Implications for Current and Future Trials
Presenter: William F. Regine, MDPresenter's Affiliation: University of Maryland Medical Center, Radiation Therapy Oncology GroupType of Session: ScientificBackground The CONKO-001 phase III trial (Oettle H, et al. JAMA. 2007;297(3):267-77)...
Prophylactic Cranial Irradiation (PCI) in Extensive Stage Small Cell Lung Cancer (ES-SCLC) (EORTC 22993-08993)
Presenter: Bernard J. Slotman, MD, PhDPresenter's Affiliation: VU University Medical Center, EORTC Radiation Oncology and Lung Cancer GroupsType of Session: ScientificBackground At the time of diagnosis, approximately 20% of patients with small...
The Impact of Boost Dose and Margins on the Local Recurrence Rate in Breast Conserving Therapy: Results From the EORTC Boost-No Boost Trial
Presenter: H. JonesPresenter's Affiliation: Holzer Cancer Center for Cancer Care, Gallipolis, OHType of Session: PlenaryBackground Breast conserving therapy (BCT),  which consists of lumpectomy followed by adjuvant radiation treatment...
The Integrin-TGFbeta Axis: Inhibition of Integrin Alpha v Beta6 Prevents Radiation-Induced Lung Fibrosis.
Presenter: S. ChengPresenter's Affiliation: New York University Medical Center, New York, NYType of Session: ScientificBackground Over 175,000 new cases of thoracic malignancies are diagnosed in the United States each year, and over half of...
Which Lung Volumes to Use for Radiotherapy Planning of Lung Cancer: Inspiration, Expiration, Averaged, or Free-breathing?
Presenter: Yixiu Kang, MDPresenter's Affiliation: M.D. Anderson Cancer CenterType of Session: PlenaryBackground Local control in patients with early stage non-small cell lung cancer (NSCLC) after conventional radiotherapy has historically been...
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