Monday, June 2 , 2008

OncoLink at ASCO
OncoLink reporters provide in-depth coverage of scientific presentations from the 44^th Annual ASCO Meeting.

A phase II randomized, placebo-controlled, double blind trial of a eugeroic agent in 642 cancer patients reporting fatigue during chemotherapy: A URCC CCOP study Presenter: G. R. MorrowPresenter's Affiliation: U. of Rochester Medical Center, Rochester, NYType of Session: ScientificBackground Cancer-related fatigue (CRF) is one of the most common side effects of cancer and its treatment, and has been...
A phase II randomized, placebo-controlled, double blind trial of a eugeroic agent in 642 cancer patients reporting fatigue during chemotherapy: A URCC CCOP study A phase II randomized, placebo-controlled, double blind trial of a eugeroic agent in 642 cancer patients reporting fatigue during chemotherapy: A URCC CCOP study Cancer-related fatigue (CRF) is one of the most common side effects of cancer and its...
A phase III randomized study comparing the effects of oxandrolone (Ox) and megastrol acetate (Meg) on lean body mass (LBM), weight (wt) and quality of life (QOL) in patients with solid tumors and weight loss receiving chemotherapy Presenter: G. J. LesserPresenter's Affiliation: Wake Forest University, Winston-Salem, NCType of Session: ScientificBackground A study by DeWys, et. al. in 1980 showed that unintentional weight loss in cancer patients is a significant problem...
A phase III randomized study comparing the effects of oxandrolone (Ox) and megestrol acetate (Meg) on lean body mass (LBM), weight (wt) and quality of life (QOL) in patients with solid tumors and weight loss receiving chemotherapy A phase III randomized study comparing the effects of oxandrolone (Ox) and megestrol acetate (Meg) on lean body mass (LBM), weight (wt) and quality of life (QOL) in patients with solid tumors and weight loss receiving chemotherapy A study by...
A Randomized Phase III Study of Gemcitabine in Combination with Radiation Therapy Versus Gemcitabine Alone in Patients with Localized, Unresectable Pancreatic Cancer: E4201 Presenter: Loehrer P.J.Presenter's Affiliation: Indiana University Melvin and Bren Simon Cancer CenterType of Session: ScientificBackground There are approximately 232,000 new cases of pancreatic cancer diagnosed annually worldwide. ...
A Randomized Phase III Study of Gemcitabine in Combination with Radiation Therapy Versus Gemcitabine Alone in Patients with Localized, Unresectable Pancreatic Cancer: E4201 A Randomized Phase III Study of Gemcitabine in Combination with Radiation Therapy Versus Gemcitabine Alone in Patients with Localized, Unresectable Pancreatic Cancer: E4201 Prior studies of gemcitabine with radiation therapy in pancreatic cancer...
ACOSG ZO531: Report on a Multicenter, Phase II Trial for Adjuvant Therapy of Resected Pancreatic Cancer Using Cisplatin, 5-FU, and Alpha-Interferon Presenter: Picozzi R.A.Presenter's Affiliation: Virginia Mason Medical Center, Seattle WashingtonType of Session: ScientificBackground Pancreatic cancer is the fourth leading cause of cancer death in the United States and in 2007, over 37,000...
ACOSG ZO531: Report on a Multicenter, Phase II Trial for Adjuvant Therapy of Resected Pancreatic Cancer Using Cisplatin, 5-FU, and Alpha-Interferon ACOSG ZO531: Report on a Multicenter, Phase II Trial for Adjuvant Therapy of Resected Pancreatic Cancer Using Cisplatin, 5-FU, and Alpha-Interferon Surgery is considered the only curative therapy for pancreatic cancer. However, 50-80% of patients...
Cancer-related fatigue interferes with activities of daily living among 753 patiens receiving chemotherapy: A URCC CCOP study Presenter: K.M. MustianPresenter's Affiliation: University of Rochester Cacner Center, Rochester, NYType of Session: ScientificBackground Cancer-related fatigue (CRF) is common in cancer patients, and may be under-diagnosed, under-recognized,...
Cancer-related fatigue interferes with activities of daily living among 753 patients receiving chemotherapy: A URCC CCOP study Cancer-related fatigue interferes with activities of daily living among 753 patients receiving chemotherapy: A URCC CCOP study Cancer-related fatigue is unfortunately a very common problem with few to no effective solutions. This study looked to...
CONKO-001: Final Results of the Randomized, Prospective, Multicenter Phase III Trial of Adjuvant Chemotherapy with Gemcitabine vs. Observation in Patients with Resected Pancreatic Cancer (PC) Presenter: Neumann J.P.Presenter's Affiliation: Charite School of Medicine, Berlin, GermanyType of Session: ScientificBackground Pancreatic cancer is the fourth leading cause of cancer death in the United States, and in 2007, over 37,000 cases...
CONKO-001: Final Results of the Randomized, Prospective, Multicenter Phase III Trial of Adjuvant Chemotherapy with Gemcitabine vs. Observation in Patients with Resected Pancreatic Cancer (PC) CONKO-001: Final Results of the Randomized, Prospective, Multicenter Phase III Trial of Adjuvant Chemotherapy with Gemcitabine vs. Observation in Patients with Resected Pancreatic Cancer (PC) This study has previously reported (Oettle H., et al....
Effect of paroxetine on depression and insomnia in 547 fatigued cancer patients undergoing chemotherapy Presenter: O.G. PaleshPresenter's Affiliation: University of Rochester Cancer Center, Rochester, NYType of Session: ScientificBackground Sleep disruption as a vegetative symptom is a cardinal symptom of psychiatric illness, and often co-occurs...
Effect of paroxetine on depression and insomnia in 547 fatigued cancer patients undergoing chemotherapy Effect of paroxetine on depression and insomnia in 547 fatigued cancer patients undergoing chemotherapy Depression and insomnia are two common issues in people with cancer. Studies have found that approximately 30% of people with cancer report...
Effects of aerobic exercise training on physical performance during myeloablative therapy Presenter: Maike de WitPresenter's Affiliation: University Clinicof Hamburg, Hamburg, GermanyType of Session: ScientificBackground The effects of cancer treatment during long or recurrent hospitalizations can induce loss of physical performance...
Effects of aerobic exercise training on physical performance during myeloablative therapy Effects of aerobic exercise training on physical performance during myeloablative therapy The benefits of exercise for people undergoing cancer therapy have been shown in previous studies. These include improvements in lung and heart function,...
Electronic self-report assessment for cancer (ESRA-C): Results of a randomized clinical trial Presenter: D.L. BerryPresenter's Affiliation: University of Washington, Seattle, WAType of Session: ScientificBackground As the healthcare milieu continuously evolves, healthcare providers are faced with the difficulties of shrinking resources,...
Prophylaxis of recurrent chemotherapy-induced oral mucositis: A phase II multicenter, randomized, placebo-controlled trial of recombinant human intestinal trefoil factor (rhITF) Presenter: N. P. BarkerPresenter's Affiliation: The GI Company Inc., Framingham, MAType of Session: ScientificBackground Oral mucositis is a common, debilitating symptom affecting many patients on high-dose chemotherapy. It is an...
Prophylaxis of recurrent chemotherapy-induced oral mucositis: A phase II multicenter, randomized, placebo-controlled trial of recombinant human intestinal trefoil factor (rhITF) Prophylaxis of recurrent chemotherapy-induced oral mucositis: A phase II multicenter, randomized, placebo-controlled trial of recombinant human intestinal trefoil factor (rhITF) Oral mucositis is a common, debilitating symptom affecting many...
Randomized Phase III Trial of Sorafenib Versus Placebo in Asian Patients with Advanced Hepatocellular Carcinoma Presenter: Cheng A.Presenter's Affiliation: National Taiwan University Hospital, Taipei, TaiwanType of Session: ScientificBackground Hepatocellular carcinoma (HCC) is the 8th most common cancer in the world, but yet it is the number three cause...
Relation between perceived cognitive function and neuropsychological performance in survivors of breast and colorectal cancer Presenter: J.L. VardyPresenter's Affiliation: Sydney Cancer Centre, Sydney, AustraliaType of Session: ScientificBackground “Chemobrain” or “chemofog” was originally described by the female breast cancer population, and...
Relation between perceived cognitive function and neuropsychological performance in survivors of breast and colorectal cancer Relation between perceived cognitive function and neuropsychological performance in survivors of breast and colorectal cancer “Chemobrain” or “chemofog” was originally described by the female breast cancer population, and...