Saturday, June 4, 2011

OncoLink at ASCO
OncoLink reporters provide in-depth coverage of scientific presentations from the Annual ASCO Meeting.

A population-based, case-control study of MC1R variants, ultraviolet light exposure, and melanoma Presenter: D. Polsky Presenter's Institution: New York University Background/Introduction It is well known that ultraviolet light (UV) exposure is associated with increased melanoma risk. In addition, several different genes have been...
A randomized phase II (RP2) trial of ridaforolimus (R) compared with progestin (P) or chemotheraphy (C) in female adult patients with advanced endometrial carcinoma Presenter: Amit M. Oza, MD Presenter's Institution: Princess Margaret Hospital, Toronto, ON, Canada Background/Introduction Endometrial cancer is the most common gynecologic malignancy, with an estimated 43,470 new cases and 7,950 deaths in...
Capecitabine versus 5-fluorouracil (5-FU)–based (neo)adjuvant chemoradiotherapy (CRT) for locally advanced rectal cancer (LARC): Long-term results of a randomized, phase III trial Presenter: Ralf Hofheinz, MD Presenter's Institution: Day Treatment Centre at the Interdisciplinary Tumour Centre Mannheim, Universitätsmedizin Mannheim, Mannheim, Germany Background 5-FU based chemoradiation prior to total mesorectal...
Effect of screening on ovarian cancer mortality in the prostate, lung, colorectal, and ovarian (PLCO) cancer randomized screening trial Presenter: Saundra Buys, MD Presenter Affiliation: University of Utah Background Ovarian cancer is a deadly disease with high case fatality rate. Approximately 22,000 women are diagnosed yearly in the U.S, and 14,000 die from the...
Impact of traditional cardiovascular disease risk factors on long-term cardiovascular outcome in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study Presenter: Gregory Armstrong, MD Presenter's Affiliation: St. Judes Children's Research Hospital Background As progress in the treatment of childhood cancers has improved survival, late effects of therapy have become more pronounced and...
Melanoma as a subsequent neoplasm in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study Presenter: A. S. Pappo Presenter's Institution: St. Jude Children's Research Hospital, Memphis, TN Background Survivors of childhood cancer are at increased risk of developing secondary malignant neoplasms (SMN). Generally speaking, children...
Predictors of early response and event-free survival in Hodgkin lymphoma (HL):PET versus CT imaging Presenter: C. L. Schwartz Presenter's Institution: Hasbro Children's Hospital/Brown University Introduction/Background Response directed therapy is an important concept in the management of Hodgkin Lymphoma (HL). In adult HL, risk...
Preoperative chemoradiotherapy and postoperative chemotherapy with 5-fluorouracil and Oxaliplatin versus 5-fluorouracil alone in locally advanced rectal cancer: First results of the German CAO/ARO/AIO-04 randomized phase III trial Presenter: Claus Roedel, MD Presenter's Institution: German Rectal Cancer Study Group; University of Frankfurt, Frankfurt, Germany Background The first German Rectal Cancer Study (CAO/ARO/AIO-04) established pre-operative chemoradiotherapy...
Results of a prospective clinical trial for VAMP alone without irradiation for pediatric favorable, early-stage Hodgkin lymphoma patients who achieve an early complete response Presenter: Monika Metzger, MD Presenter's Affiliation: St. Jude Children's Research Hospital Background Low-risk Hodgkin lymphoma typically refers to stage I-IIA, non-bulky disease in less than 3 sites, and without extranodal involvement. ...