OncoLink at ASTRO 2012

Coverage of the 2012 Annual Meeting of the American Society for Therapeutic Radiology And Oncology, ASTRO, held in Boston, MA.

A Decision Analysis to Assess the Value of Prostate Cancer Screening: A Shift in Focus from Prostate Cancer-specific Mortality to Distant Metastasis-Free Survival Abstract Number: 140 Presenter: Arie Dosoretz, MD Presenter's Affiliation: Yale-New Haven Hospital Background Prostate cancer is the most common cancer in men and the 2nd leading cause of cancer death. Prostate cancer screening has been...
Beliefs About the Effectiveness of Palliative Radiation Therapy among Patients with Incurable Lung Cancer Abstract number: Plenary #6 Presenter: Aileen Chen, MD, MPP Affiliation: Brigham and Women's Hospital and Dana-Farber Cancer Institute Background Metastatic lung cancer is almost always incurable, and radiation therapy is a mainstay of...
Cardiac Toxicity is Not Increased 25 Years After Treatment of Early Stage Breast Carcinoma With Mastectomy or Breast Conservation Therapy From the National Cancer Institute Randomized Trial Abstract # 87 Presenting Author: Charles B. Simone, II, MD Presenting Author's Affiliation: Hospital of the University of Pennsylvania, Department of Radiation Oncology, Philadelphia, PA Background The current options for the treatment of...
Determinants of Patient Satisfaction for Patients Receiving Radiation Therapy Abstract # 247 Presentation Date: October 30, 2012 Presenter: Robin Famiglietti, FACHE, MBA Presenter's Affiliation: The University of Texas, MD Anderson Cancer Center Background Overall patient satisfaction is an important point of...
Does Patient Life Expectancy (LE) Affect Receipt of Routine Cancer Screening in the United States? A Population-Based Study Abstract Number: 226 Presenting Author: Trevor Royce, MS4 Affiliation: University of North Carolina at Chapel Hill, Chapel Hill, NC Background Routine cancer screening methods exist for a variety of malignancies including prostate cancer,...
Early Patterns of Failure in a Prospective Trial of Concomittant Docetaxel and Proton Therapy for High-risk Prostate Cancer Abstract Number: 226 Presenter: Nancy Mendenhall, MD Presenter's Affiliation: The University of Florida Proton Therapy Institute, Jacksonville, FL Background Patients with high-risk prostate cancer are at increased risk of distant...
Interim Toxicity Results from RAPID: A Randomized Trial of Accelerated Partial Breast Irradiation (APBI) Using 3D Conformal External Beam Radiation Therapy (3D-CRT) Abstract number: Plenary # 5 Presenter: Timothy J Whelan Affiliation: Ontario Clinical Oncology Group Background Accelerated partial breast irradiation (APBI) is defined as the delivery of large dose per fraction to the surgical cavity as...
Interval Between Hysterectomy and Start of Radiation Treatment is Predictive of Recurrence in patients with endometrial carcinoma. A single Institution experience Abstract number: 238 Presenter: M. A. Elshaikh presenting for Richard Cattaneo Affiliation: Henry Ford Health System Background Endometrial cancer is the most common gynecologic malignancy in the U.S. and the second leading cause of...
Is Stereotactic Body Radiation Therapy (SBRT) an Attractive Option for Unresectable Liver Metastases? Early Results From a Phase II Trial Presenter: Stefano Arcangeli, MD Affiliation: Istituto Clinico Humanitas, Italy Background Unresectable liver metastases originating from solid tumors present a therapeutic challenge to treatment providers. Attempts at local control...
Late Breaking Abstract 1: N09C6 (Alliance) - A Phase III, Randomized Double-Blind Study of Doxepin Rinse versus Placebo in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Head and Neck Radiotherapy with or without Chemotherapy Abstract # 1 (late breaking abstract) Presentation Date: October 29, 2012 (Recorded due Hurricane Sandy) Presenter: Robert C. Miller Presenter's Affiliation: Mayo Clinic, Minnesota Background Radiation and chemotherapy induced oral...
Low-risk Breast Ductal Carcinoma In Situ (DCIS): Results From the Radiation Therapy Oncology Group 9804 Phase 3 Trial Abstract # 11 Presenter: Beryl McCormick Affiliation: Memorial Sloan Kettering Cancer Center, New York Background Several randomized clinical trials have demonstrated the benefit of adjuvant radiation therapy on local control for women with...
Memantine for the Prevention of Cognitive Dysfunction in Patients Receiving Whole-Brain Radiation Therapy (WBRT): First Report of RTOG 0614, a Placebo-controlled, Double-blind, Randomized Trial Abstract # 2 Presentation Date: October 29, 2012 (Recorded due Hurricane Sandy) Presenter: Nadia Laack, MS, MD Presenter's Affiliation: Radiation Therapy Oncology Group Background Brain metastases is the most common form of intracranial...
Patient Reported Quality of Life in Prostate Cancer Patients Treated with 3D conformal, Intensity Modulated or Proton Beam Radiation Therapy Abstract # 30 Presentation Date: October 28, 2012 Presenter: Phillip Gray, MD Presenter's Affiliation: Harvard Radiation Oncology Program Background Limited data exist comparing contemporary technologies in the treatment of prostate...
Patterns of Relapse From a Phase III Study of Response-based Therapy for Intermediate-risk Hodgkin Lymphoma (AHOD0031): A Report from the Children’s Oncology Group Abstract # 12 Presenter: KV.V. Dharmarajan Presenter's Affiliation: Memorial Sloan Kettering Cancer Center Background Hodgkin’s lymphoma constitutes about 6% of childhood cancers and is most common in children > 10 years. With...
Poor Glycemic Control During Radiochemotherapy Contributes to Reduced Local Control and Overall Survival in Patients with Non-Small Cell Lung Cancer Abstract Number: 171 Presenting Author: Mohamad Fakhreddine, MS Affiliation: University of Texas MD Anderson Cancer Center, Houston, TX Background Diabetes mellitus (DM) is known to be associated with a higher incidence of malignancies as...
Proton Radiotherapy For High-risk Pediatric Medulloblastoma: Outcomes For Very Young Children Treated With Upfront Chemotherapy Abstract number: 161 Presenter: Rachel Jimenez, MD Affiliation: Harvard Radiation Oncology Program Background Medulloblastoma is the most common brain tumor of childhood Appropriate treatment includes maximal surgical resection, followed...
Proton Therapy for Low Grade Glioma: A Pilot Study Abstract # 91 Presenter: Helen Shih, MD MS MPH Affiliation: Massachusetts General Hospital Background Given the moderate long-term survival in LGG, many patients will live long enough to benefit from reduction in long-term...
Radiation Modality is a Strong Predictor for Postoperative Pulmonary and GI Complications after Trimodality Therapy for Esophageal Cancer Abstract # 100 Presenter: J. Wang, MD Presenter's Affiliation: The University of Texas, MD Anderson Cancer Center Background Esophageal cancer is the sixth leading cause of death from cancer worldwide. Operable patients are typically treated...
Radiation Therapy Protocol Deviations are Associated With Inferior Clinical Outcomes: A Meta-analysis of Cooperative Group Clinical Trials Presenting Author: Nitin Ohri, MD Presenting Author Affiliation: Kimmel Cancer Center, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA Background Quality assurance procedures are commonly...
Repeat CT Simulation during Whole Breast Irradiation Can Influence the Selection of Treatment Modality for Breast Cancer Tumor Bed Boost Abstract Number: 271 Presenting Author: N. Novalchuk, MD Affiliation: Boston Medical Center, Harvard Medical School, Boston, MA Background In the United States, radiation boost to the tumor bed is routinely delivered as part of...
Results of a Prospective Randomized Double-blind Placebo Controlled Trial Evaluating the Use Prophylactic Sildenafil Citrate During Radiation Therapy in the Treatment of Prostate Cancer Presenting Author: Michael J. Zelefsky, MD Presenting Author Affiliation: Sloan-Kettering Cancer Center, New York, NY Purpose/Objective(s) Penile rehabilitation has emerged as an important entity...
Risk of Fatal Cerebrovascular Accidents After External Beam Radiotherapy for Early Stage Glottic Larynx Cancer Abstract Number: 150 Presenting Author: Justin E. Bekelman, MD (on behalf of Samuel Swisher-McClure, MD) Affiliation: Hospital of the University of Pennsylvania, Department of Radiation Oncology, Philadelphia, PA Background Early-stage...
Second Cancer Risk 40 Years After Hodgkin Lymphoma Treatment Presenter: Berthe Aleman, MD, PhD Affiliation: The Netherlands Cancer Institute Background Large studies have identified increased risk of breast and other cancers in survivors of Hodgkin lymphoma, partially due to late toxicity of...
Survival of Adult Rhabdomyosarcoma Patients Treated on Multimodality Protocols Abstract Number: 339 Presenting Author: Naamit Gerber, MD Affiliation: Memorial Sloan Kettering Cancer Center, New York, NY Background Rhabdomyosarcoma (RMS) is a pediatric sarcoma rarely occurring in adults. Greater than 50% of cases are...