Dear OncoLink "Ask The Experts,"
I was diagnosed with Stage 1A fallopian tube cancer in July. The surgery was performed by a surgeon specializing in GYN Oncology. Why does your website say that the 5-year survival rate for Stage 1A is 51% (or thereabouts), whereas all other websites I've found quote 91% 5-year survival for Stage 1A fallopian tube cancer?
Carolyn Vachani RN, MSN, AOCN, OncoLink's Nurse Educator, responds:
The numbers we have posted are what most oncology textbooks quote, which are based on some older clinical studies. In these studies, fallopian tube cancer stage I patients did not receive any adjuvant therapy (meaning chemotherapy after surgery). Stage I tumors invade the mucosa, although they do not penetrate it. According to our experts, nowadays it is generally thought and recommended that stage I patients receive some adjuvant chemotherapy. With this additional therapy, properly-staged 1A patients could have 5-year survival in the 80-90% range. There are only about 300 total cases of fallopian tube cancer a year (this includes all stages). These small numbers have not allowed for many controlled studies to get accurate prognostic information from, so this 80-90% range is more based on expert opinion, not necessarily hard data.
Feb 26, 2014 - Among women with mutations in BRCA1 or BRCA2, oophorectomy reduces the risk of developing ovarian, fallopian tube, or peritoneal cancer by 80 percent and reduces the risk of death by 77 percent, with greater BRCA1 benefit seen with earlier removal, according to a study published online Feb. 24 in the Journal of Clinical Oncology.