Kevin Fox, MD
Last Modified: June 9, 2002
Dear OncoLink "Ask The Experts,"
Kevin Fox, MD Assistant Director, Clinical Affairs and Associate Professor of Hematology/Oncology at the Abramson Cancer Center of the University of Pennsylvania responds:
Recommending for or against herceptin has nothing to do with the patient age or menopausal status. The recommendations regarding herceptin are based on the biopsy report that specifically evaluates a marker called HER-2/nue. Patients that have over-expression of this marker are candidates for herceptin therapy. It has thus far been used in patients with metastatic breast cancer and high risk locally advanced breast cancer. There are ongoing studies evaluating the best combination of herceptin with chemotherapy and the appropriate timing of administration. The safety and effectiveness of herceptin has not been evaluated in patients as treatment for "early stage" breast cancer. This is part of a current research trial.
May 16, 2014 - In estrogen receptor-positive breast cancer, obesity is positively associated with breast cancer mortality only among pre-/peri-menopausal women, according to new research. These findings have been released in advance of presentation at the annual meeting of the American Society of Clinical Oncology, to be held from May 30 to June 3 in Chicago.
Feb 4, 2011
Jun 16, 2011