Tamoxifen for DCIS

Kevin Fox, MD
Last Modified: February 3, 2002

Share article


Question

Dear OncoLink "Ask The Experts,"

I recently was diagnosed with high nuclear grade, multifocal, comedo-necrosis type DCIS. I underwent a modified radical mastectomy. No invasive cancer was found, & all 13 nodes excised were negative.

Estrogen receptor status was not done as the clinical guidelines in Canada indicate no further treatment is necessary. Is Tamoxifen warranted as further treatment in this type of DCIS, esp. for protection for the other breast? Is it only effective on ER+ receptors?  


Answer

Kevin Fox, MD, Assistant Director, Clinical Affairs and Associate Professor of Hematology/Oncology at the Abramson Cancer Center of the University of Pennsylvania responds:

Tamoxifen will benefit you only insofar as it may lower the risk of breast cancer in the opposite breast. Your DCIS has been treated adequately with surgery; tamoxifen will provide no additional treatment benefit in regard to the breast that was removed. Estrogen receptors are not factored into the management of DCIS as opposed to invasive cancer.



News
Transdermal 4-Hydroxytamoxifen Gel Beneficial in DCIS

Jul 22, 2014 - For women with ductal carcinoma in situ, 4-hydroxytamoxifen gel applied to breast skin has a similar antiproliferative effect as oral tamoxifen, according to a study published in the July 15 issue of Clinical Cancer Research.



I Wish You Knew

How cancer patients have changed my life

View More



Blogs and Web Chats

OncoLink Blogs give our readers a chance to react to and comment on key cancer news topics and provides a forum for OncoLink Experts and readers to share opinions and learn from each other.




OncoLink OncoPilot

Facing a new cancer diagnosis or changing the course of your current treatment? Let our cancer nurses help you through!

Learn More