Proton Therapy for Anal Cancer

Last Modified: April 20, 2008

Share article


Dear OncoLink "Ask The Experts,"

Is the new proton beam radiation a viable option for anal cancers?


James M. Metz, MD, Editor-in-Chief of OncoLink and Assistant Professor of Radiation Oncology at the Hospital of the University of Pennsylvania, responds:

Proton beam therapy is being explored as a possible form of treatment for a number of cancers. To date, no clinical studies have been done specifically treating anal cancer. However, there is interest in expanding the use of protons to treat a number of gastrointestinal malignancies. Because many of these cancers are currently treated with combined chemotherapy and radiation therapy, which has a higher complication rate then either therapy alone, proton-based radiation may offer benefits due to the superior dose deposition within the target and reduced dose to normal organs – resulting in potentially fewer and less severe side effects. I am not aware of any clinical trials that have been started specifically for anal cancer. As the availability of proton therapy expands, this will certainly become an area of clinical investigation.

I Wish You Knew

How cancer patients have changed my life

View More

Blogs and Web Chats

OncoLink Blogs give our readers a chance to react to and comment on key cancer news topics and provides a forum for OncoLink Experts and readers to share opinions and learn from each other.

OncoLink OncoPilot

Facing a new cancer diagnosis or changing the course of your current treatment? Let our cancer nurses help you through!

Learn More