Alan J. Wein, MD
Last Modified: February 3, 2002
Dear OncoLink "Ask The Experts,"
I'm 63 years old male, in good health I had radical prostatectomy in September 2000. I had a normal recovery except that, to date, I've not recovered normal bladder control (at best still use 2 to 3 pads a day). I'm dry at night while sleeping and on average urinate 2 or 3 times. I've tried medication (Ditropan/15 mg and medication to "tighten/contract" bladder muscle) with no or marginal effect. I've also had two procedures for collagen implant. The first using collagen -this worked for about 36 hours after which I started leaking again. The second used a more durable material - again it seemed to work for about 24 hours after which time I started leaking at a higher rate then before the procedure. What is next feasible course of treatment that I should pursue?
Alan J. Wein, MD, Professor and chair of the Division of Urology at the University of Pennsylvania School of Medicine and Chief of Urology at the Hospital of the University of Pennsylvania, responds:
In my experience, if continence (the ability to control urine) has not returned 15 months following radical prostatectomy, it is likely that it will not return without further treatment. The great majority of cases with incontinence post prostatectomy are due to sphincter control rather than a problem with the bladder. Therefore, Ditropan will not help. Therapy aimed at improving outlet resistance (tightening the sphincter) will help. Collagen implant procedures may take as many as four attempts to achieve results. Normally evaluation consists of pressure flow urodynamic studies with measurement of valsalva leak point of pressure and a cystoscopy.
Oct 11, 2010 - Radical prostatectomy, external-beam radiotherapy, and brachytherapy result in several quality-of-life issues after prostate cancer treatment in patients not receiving adjuvant hormonal treatment, including either improvement in or worsening of urinary irritative-obstructive symptoms in addition to the more commonly discussed sexual and incontinence issues, according to research published online Oct. 4 in the Journal of Clinical Oncology.
Jul 11, 2011