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Frequently Asked Questions / Types of Cancer / Breast Cancer / Breast Cancer
Last Modified: January 10, 2006
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Dear OncoLink "Ask The Experts,"
I am a 69 year old male who was recently diagnosed with breast cancer. My doctor has never seen this before in a man. How is this treated compared to a woman with breast cancer?
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Carolyn Vachani RN, MSN, AOCN, OncoLink's Nurse Educator, responds:
Breast cancer in men accounts for about 1% of all breast cancers and about 0.2% of all cancers in men. There will be about 1,690 new cases of male breast cancer in 2005, compared to 213,000 cases in women. Risk factors for the development of male breast cancer include Klinefelter's syndrome, being of Jewish descent, mumps orchitis, a family history of male or female breast cancer and family cancer syndromes (BRCA1 & 2 gene abnormalities account for 40% of cases).
The predominant presenting symptom is a mass in the breast. Other symptoms and signs of male breast cancer include nipple discharge (particularly if bloody), nipple retraction and skin ulceration. Mammograms are difficult to perform, particularly on thin men, so a biopsy should be done on a suspicious lump.
The treatment of male breast cancer is similar to that of female breast cancer. Historically, radical mastectomy was the treatment of choice, but surgeons may perform less aggressive surgery if the cancer is small and doesn't involve underlying chest muscle. The use of radiation, chemotherapy and hormone therapy (tamoxifen) after surgical removal of the tumor follows the same principles as in female breast cancer.
Dr. Metz talks about how caring for cancer patients has affected his life. Read more.
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Calcium Leucovorin, Citrovorum Factor, Folinic Acid
Cladribine (2-CDA, Leustatin®)
Cyclophosphamide (Cytoxan®, Neosar®, Endoxan®)
Cyclosporine (Neoral®, Sandimmune®, Restasis®, Gengraf®)
Cytarabine (Cytosar-U®, Ara-C)
Irinotecan (Camptosar®, CPT-11)
Leucovorin (Calcium Leucovorin, Citrovorum Factor, Folinic Acid)
Calcium Leucovorin, Citrovorum Factor, Folinic Acid
Leucovorin (Calcium Leucovorin, Citrovorum Factor, Folinic Acid)
Leuprolide Acetate (Lupron®, Lupron Depot®, Eligard®, Prostap®, Viadur®) - For Men
Leuprolide Acetate (Lupron®, Lupron Depot®, Eligard®, Prostap®, Viadur®) - For Women
Lupron®, Lupron Depot®, Eligard®, Prostap®, Viadur®
Lupron®, Lupron Depot®, Eligard®, Prostap®, Viadur®
Busulfan (Myleran®, Busulfex®)
Intravesicular Mitomycin (Mutamycin®, Mitomycin-C, given into the bladder)
Mechlorethamine (Mustargen®, Nitrogen Mustard)
mechlorethamine, mustine, Mustargen®
Megestrol (Megace®, Megace-ES®)
Mercaptopurine (Purinethol®, 6-MP)
Methotrexate (Mexate®, Folex®, Rheumatrex®, Amethopterin, MTX)
Mexate®, Folex®, Rheumatrex®, Amethopterin, MTX
Mitomycin (Mutamycin®, Mitomycin-C)
Morphine Sulfate (Given by IV)
Morphine Sulfate (MS Contin®, Avinza®, Kadian®, Oramorph SR®)
MS Contin®, Avinza®, Kadian®, Oramorph SR®
Mutamycin®, Mitomycin-C, given into the bladder
Nitrogen mustard (mechlorethamine, mustine, Mustargen®)
Bendamustine Hydrochloride (Treanda®)
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Bexarotene Gel (Targretin® Gel Formulation)
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Thioguanine (6-TG, Thioguanine Tabloid®)
Toposar®, VePesid®, Etopophos®,VP-16
Trelstar LA® and Trelstar Depot®
Tretinoin (Vesanoid®, All-Trans-Retinoic Acid, ATRA)
Triptorelin (Trelstar LA® and Trelstar Depot®)


