Last Modified: June 10, 2007
Dear OncoLink "Ask The Experts,"
I had a radical prostatectomy in September 2006. Why would I have anything but a 0.0 PSA at this time? It's very low (PSA=0.08) but I'm not clear as to why ANY exists without a prostate.
David I. Lee, MD, Chief of the Division of Urology at Penn Presbyterian Medical Center, responds:
We aim for a serum PSA that is <0.1 ng/mL. We do not panic when a PSA is still detectable after prostatectomy. There can be benign prostate cells in the pelvis. However, a PSA that steadily climbs into the 0.2 ng/mL range and higher warrants a careful evaluation for the presence of recurrent disease. The adrenal gland can also make a very small amount of PSA.
Oct 17, 2014 - Prostate-specific antigen recurrence may be overdetected after radical prostatectomy, according to research published in the Oct. 15 issue of Clinical Cancer Research.