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Frequently Asked Questions / Types of Cancer / OncoLink Vet / Veterinary Oncology
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Last Modified: September 17, 2012
Question
Is the Wisconsin protocol the most effective treatment for lymphoma? What are the chances of a cure or is this therapy really to buy her time? Is there a less expensive but maybe not too less effective treatment? I read something about using CCNU alone.
Erika Krick, VMD, DACVIM Veterinary Medical Oncologist, University of Pennsylvania, responds:
Answer
CHOP-based protocols (the Wisconsin protocol is one of these) are considered to be the most effective treatment for lymphoma in dogs. These protocols use a combination of prednisone, cyclophosphamide, vincristine, and doxorubicin. The chance of a cure is low, but the chance of remission is high for most dogs. Other less expensive options include prednisone alone, prednisone and CCNU (lomusine), and doxorubicin alone. I recommend that you consult with your veterinarian or an oncologist about these options.
Learn more about lymphoma in dogs.
This question and answer was part of the OncoLink Brown Bag Chat Series. View the entire transcript from When a Beloved Pet has Cancer.
What every person should know about screening, learning about your disease and the importance of cllinical research. Read more.
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Calcium Leucovorin, Citrovorum Factor, Folinic Acid
Cladribine (2-CDA, Leustatin®)
Cyclophosphamide (Cytoxan®, Neosar®, Endoxan®)
Cyclosporine (Neoral®, Sandimmune®, Restasis®, Gengraf®)
Cytarabine (Cytosar-U®, Ara-C)
Irinotecan (Camptosar®, CPT-11)
Leucovorin (Calcium Leucovorin, Citrovorum Factor, Folinic Acid)
Calcium Leucovorin, Citrovorum Factor, Folinic Acid
Leucovorin (Calcium Leucovorin, Citrovorum Factor, Folinic Acid)
Leuprolide Acetate (Lupron®, Lupron Depot®, Eligard®, Prostap®, Viadur®) - For Men
Leuprolide Acetate (Lupron®, Lupron Depot®, Eligard®, Prostap®, Viadur®) - For Women
Lupron®, Lupron Depot®, Eligard®, Prostap®, Viadur®
Lupron®, Lupron Depot®, Eligard®, Prostap®, Viadur®
Busulfan (Myleran®, Busulfex®)
Intravesicular Mitomycin (Mutamycin®, Mitomycin-C, given into the bladder)
Mechlorethamine (Mustargen®, Nitrogen Mustard)
mechlorethamine, mustine, Mustargen®
Megestrol (Megace®, Megace-ES®)
Mercaptopurine (Purinethol®, 6-MP)
Methotrexate (Mexate®, Folex®, Rheumatrex®, Amethopterin, MTX)
Mexate®, Folex®, Rheumatrex®, Amethopterin, MTX
Mitomycin (Mutamycin®, Mitomycin-C)
Morphine Sulfate (Given by IV)
Morphine Sulfate (MS Contin®, Avinza®, Kadian®, Oramorph SR®)
MS Contin®, Avinza®, Kadian®, Oramorph SR®
Mutamycin®, Mitomycin-C, given into the bladder
Nitrogen mustard (mechlorethamine, mustine, Mustargen®)
Bendamustine Hydrochloride (Treanda®)
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Bexarotene Gel (Targretin® Gel Formulation)
Etoposide (Toposar®, VePesid®, Etopophos®,VP-16)
Thioguanine (6-TG, Thioguanine Tabloid®)
Toposar®, VePesid®, Etopophos®,VP-16
Trelstar LA® and Trelstar Depot®
Tretinoin (Vesanoid®, All-Trans-Retinoic Acid, ATRA)
Triptorelin (Trelstar LA® and Trelstar Depot®)

