Stephen C. Rubin, MD
Last Modified: May 26, 2002
Dear OncoLink "Ask The Experts,"
Twenty-three years ago I had cervical cancer and a hysterectomy was done. Now I have been diagnosed with ovarian cancer. Is there a link between the two and is my ovarian cancer a secondary cancer. I have been on hormone replacement for the past 10 years.
Stephen C. Rubin, MD, Professor and Chief of the Division of Gynecologic Oncology, University of Pennsylvania Health System, responds:
There is no link between cervical and ovarian cancers, and no reason to think that your ovarian cancer is a reoccurrence of the cervical cancer you had 23 years ago. The evidence is that hormone replacement therapy does not affect the risk of ovarian cancer. I hope you do as well with the ovarian cancer as you did with the cervical.
Jan 26, 2015 - Women using hormonal contraception who tested positive for the human papillomavirus are not at increased risk of developing cervical cancer, according to a study published in the May issue of the American Journal of Obstetrics & Gynecology. However, use of depot-medroxyprogesterone acetate (DMPA) is linked with higher risk of oncogenic HPV infection.