OncoGel and Ovarian Cancer

Last Modified: February 12, 2006

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Question

Dear OncoLink "Ask The Experts,"

Do you have any knowledge or experience with use of OncoGel to deliver paclitaxel directly into ovarian cancer masses? I have recurrent disease. Thank you.

Answer

Stephen C. Rubin, MD, Professor and Chief of the Division of Gynecologic Oncology, University of Pennsylvania Health System, responds:

OncoGel is an experimental, long-acting form of paclitaxel chemotherapy that is currently undergoing clinical testing for direct needle injection into tumor masses. We will await the results of these trials. However, direct needle injection is unfortunately not likely to play any role in this disease, as ovarian cancer typically spreads beyond the injected mass to involve many different areas and organs within the abdominal cavity.