DCIS Hormone Therapy

Last Modified: January 19, 2007

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Question

Dear OncoLink "Ask The Experts,"

Has any new information come out at recent conferences about the addition of aromatase inhibitors after 2.5 yrs. of Tamoxifen for estrogen-positive DCIS, after a lumpectomy with clear margins? A consultation indicated that it was not necessary in my case. In my research, I find that 5 yrs. of Tamoxifen is considered adequate for DCIS.

Answer

Kevin R. Fox, MD, Assistant Director, Clinical Affairs and Associate Professor of Hematology/Oncology at the Abramson Cancer Center of the University of Pennsylvania, responds:

Your research is correct. The current standard for DCIS is tamoxifen for five years. There is no role for aromotase inhibitors in the treatment of DCIS at this time.



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