Multiple Mast Cell Tumors in Dogs
They were all grade I. He said the margins were clear. But why does she have them all over her body? He said I should have an aspirate taken from her spleen, liver, and bone marrow. He said he has never seen multiple sites of grade I tumors before.
In general, the treatment of grade I mast cell tumors is surgical removalif surgery obtains "clean" margins then this is usually adequate. Grade I mast cell tumors generally have a relatively benign behavior.
However, mast cell tumors can behave unpredictably. The fact that there are multiple tumors indicates that some form of systemic treatment might be warranted (such as prednisone or other chemotherapy)however this depends to a large extent on the results of the staging evaluation.
We have seen a group of dogs that develop multiple mast cell tumors either with multiple tumors at the same time or multiple tumors over the years. Some dogs and some breeds of dogs seem predisposed to developing multiple tumors. However, if there is no evidence of spread to lymph nodes or other organs, many of these dogs can be successfully treated by surgical removal of the tumors particularly if the tumors are small (with or without some form of chemotherapy) and close monitoring for new tumors.
If you or your veterinarian have not already done so, please consult a qualified veterinary oncologist to further explore the treatment options for your pet.