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Gleevec and BMT

Question

Dear OncoLink "Ask The Experts,"
Our 14 year old son was diagnosed with Chronic Myelogenous Leukemia 6 weeks ago. He is on Gleevec. We have been considering Bone Marrow Transplant but heard that Gleevec may be contraindicated in doing a BMT. Can you shed any light on this?

Answer

Selina M. Luger, MD, Director of the Leukemia Program and Assistant Professor of Medicine at the University of Pennsylvania, responds:

Being on Gleevec in no way makes patients ineligible for a bone marrow transplant. However, sometimes, the Gleevec is discontinued for some period of time before the transplant is performed.

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