|David A. Lieberman, David G. Weiss, John H. Bond, et al.|
|Abramson Cancer Center of the University of Pennsylvania|
| Last Modified: November 1, 2001
Reviewers: Li Liu, MD
Précis: Colonoscopy is favored for colorectal cancer screening in asymptomatic adults
IntroductionAlmost all colorectal cancers arise from adenomatous polyps that develop over a period of years. During this time, polyps can be detected and then removed by colonoscopic polypectomy. It has long been thought by many physicians that colonoscopy is superior to sigmoidoscopic screening in detecting asymptomatic colorectal cancers or polyps associated with a high risk of cancer. In this study, researchers looked at the prevalence and location of colonic neoplasia in asymptomatic patients.
MethodA total of 3,121 asymptomatic adults aged 50 to 75 years underwent colonoscopy.
DiscussionThe authors concluded that colonoscopy should be used instead of sigmoidoscopy in screening for colorectal cancer. This study reinforced the growing concern among physicians that flexible sigmoidoscopy alone to screen persons for colorectal cancer is suboptimal.