|Marlene H. Frost, Daniel J. Schaid, Thomas A. Sellers, et al.|
|Abramson Cancer Center of the University of Pennsylvania|
| Last Modified: November 1, 2001
Reviewers: Li Liu, MD
Précis: High satisfaction following prophylactic bilateral mastectomy
IntroductionThe improved availability to identify women at high risk for breast cancer, such as through genetic testing for BRCA1 and BRCA2 mutation, has intensified the need to define the benefits and risks of early detection and protective measures for such women. Prophylactic mastectomy is one option for preventing breast cancer in women at high risk for the disease. However, the social and psychological impact of bilateral mastectomy in women with breast cancer remains unclear. In this study, researchers assessed psychosocial and social outcomes, and overall satisfaction of prophylactic mastectomy.
MethodA total of 572 women with a family history of breast cancer who had a bilateral prophylactic mastectomy between 1960 and 1993 were included.
ResultsAfter a mean follow-up of 14.5 years,
DiscussionIn the study, most women were satisfied after bilateral prophylactic mastectomy and report much less concern about developing breast cancer.