Table of Contents
1
UI - 11770299
AU - Kimmelman A; Liang BC
TI -
Familial neurogenic tumor syndromes.
SO - Hematol Oncol Clin North Am 2001 Dec;15(6):1073-84
AD - Mount Sinai-NYU Medical Center and Health Systems, Derald H. Ruttenberg
Cancer Center, New York, New York, USA.
Cancer caused more than 0.5 million deaths in the United States in 2000.
This estimate includes patients who have a genetic predisposition to
neoplastic disease, including brain neoplasms. Familial tumor syndromes
are important to identify clinically because family members require high
degrees of monitoring and genetic counseling. Study of these individuals
and families has led to the discovery of genes that are an intrinsic
aspect of cell regulation and will continue to be relevant in defining
mechanisms of neoplastic development in brain and other tissues.
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