Table of Contents
1
UI - 11993209
AU - Okada T; Tsukazaki H; Itoh M; Nishio Y; Muro H
TI -
[Renal pelvic cancer representing G-CSF production and hypercalcemia
simultaneously: a case report]
SO - Hinyokika Kiyo 2002 Mar;48(3):155-8
AD - Department of Urology, Shizuoka General Hospital.
A 73-year-old man was admitted to the hospital complaining of gross
hematuria and left flank pain. Abdominal ultrasonography and computed
tomography revealed a left renal tumor with extracapsular extension.
Laboratory data showed marked leukocytosis of 121,000/mm3 and
hypercalcemia of 12.3 mg/dl without any findings of inflammatory disease
or bone metastasis. Enzyme immunoassay of the serum demonstrated a high
level of granulocyte colony-stimulating factor (250 pg/ml) and
parathyroid hormone-related protein (1,069 pmol/l). Pathological
diagnosis of needle biopsy specimen of the primary tumor was
transitional cell carcinoma which was suspected to have originated from
renal pelvis. Immunohistochemical examination with anti-granulocyte
colony-stimulating factor monoclonal antibody demonstrated granulocyte
colony-stimulating factor production in cancer cells. The patient
underwent a course of systemic chemotherapy, but died two months after
diagnosis. To our knowledge, this is the first report of renal pelvic
cancer representing granulocyte colony-stimulating factor production and
hypercalcemia simultaneously.
2
UI - 11993213
AU - Hasumi H; Mokuo Y; Sano K; Miura K
TI -
[Ureteral inverted papilloma: a case report]
SO - Hinyokika Kiyo 2002 Mar;48(3):171-3
AD - Department of Urology, Hamaoka Municipal Hospital.
A 43-year-old man presented with left hydronephrosis, incidentally found
by ultrasonography. He had undergone transurethral bladder tumor
resection when he was 29 years old. Cystoscopy revealed a tumor
protruding from the left ureteral orifice. Left partial ureterectomy was
performed, and its histopathological diagnosis was ureteral inverted
papilloma. He has remained free of disease for 18 months after the
surgery.
3
UI - 11993217
AU - Ueda T; Okumi M; Ichimaru N; Itoh K; Matsuoka Y; Fujimoto N
TI -
[Mucinous adenocarcinoma of the renal pelvis in the horseshoe kidney: a
case report]
SO - Hinyokika Kiyo 2002 Mar;48(3):187-9
AD - Department of Urology, Osaka Prefectural General Hospital.
A 41-year-old man with macroscopic hematuria and abdominal fullness was
referred to our hospital. Computed tomography (CT) revealed a left renal
pelvic tumor in the horseshoe kidney. We performed left heminephrectomy
and ureterectomy. The pathological diagnosis was the mucinous
adenocarcinoma in the renal pelvis. He received postoperative adjuvant
chemotherapy (CAP therapy). He died of retroperitoneal recurrence 8
months postoperatively. In the literature we found 95 cases of primary
adenocarcinoma in the renal pelvis including our case.
4
UI - 11957151
AU - Seibel JL; Prasad S; Weiss RE; Bancila E; Epstein JI
TI -
Villous adenoma of the urinary tract: a lesion frequently associated
with malignancy.
SO - Hum Pathol 2002 Feb;33(2):236-41
AD - Department of Urology, The Johns Hopkins Hospital, Baltimore, MD 21231,
USA.
Villous adenomas arising in the urinary tract are rare. We identified 18
cases of villous adenomas of the bladder, urachus, and prostatic
urethra. Patients ranged in age from 53 to 93 years with an average age
of 69.6 years and a male preponderance of 67%. In six cases (33%), the
lesion was pure villous adenoma. In three cases (17%), there was villous
adenoma with in situ adenocarcinoma. In six cases (33%) there was
villous adenoma with in situ and infiltrating adenocarcinoma. One case
(6%) had villous adenomas with in situ (noninvasive) papillary
urothelial carcinoma. One case (6%) had villous adenomas with in situ
adenocarcinoma and in situ papillary (noninvasive) and infiltrating
urothelial carcinoma. The remaining case (6%) had villous adenoma with
in situ and infiltrating adenocarcinoma and in situ (noninvasive)
papillary and infiltrating urothelial carcinoma. Clinical outcome was
available in eight of the cases, with a mean follow-up of 4.6 years. No
evidence of recurrence was found in two patients with pure villous
adenoma or in two patients with villous adenoma and only in situ
adenocarcinoma, all of whom were treated by nonradical excision.
However, two of three cases with infiltrating cancer developed distant
metastases despite radical surgery; the remaining patient was
disease-free 11 years after transurethral resection. The case with
villous adenoma and in situ urothelial carcinoma progressed to
sarcomatoid urothelial carcinoma following partial cystectomy. Eight of
10 villous adenomas cases studied expressed the epitope for mAbDas1,
found on colonic epithelium and primary adenocarcinomas of the bladder
and urachus but not on normal or neoplastic urothelium. This study
expands the spectrum of histologic features accompanying villous
adenomas of the urinary tract. Coexisting infiltrating adenocarcinoma is
often present, necessitating thorough sampling of any lesion diagnosed
by biopsy as villous adenoma. Pure villous adenoma and those
well-sampled lesions also containing in situ adenocarcinoma portend a
favorable prognosis, even without radical treatment. Coexisting in situ
or infiltrating carcinoma suggests a more aggressive course.
Histologically, immunohistochemically, and prognostically, these lesions
appear analogous to their counterparts in the intestine. Copyright 2002,
Elsevier Science (USA). All rights reserved.
5
UI - 11872045
AU - Christopher N; Arya M; Brown RS; Payne HA; Woodhouse CR; Ralph DJ
TI -
Penile preservation in squamous cell carcinoma of the bulbomembranous
urethra.
SO - BJU Int 2002 Mar;89(4):464-5
AD - Institute of Urology, University College London, London, UK.
6
UI - 11992840
AU - Yang MH; Chen KK; Yen CC; Wang WS; Chang YH; Huang WJ; Fan FS; Chiou TJ;
TI -
Liu JH; Chen PM
Unusually high incidence of upper urinary tract urothelial carcinoma in
Taiwan.
SO - Urology 2002 May;59(5):681-7
AD - Division of Medical Oncology, Department of Medicine, Taipei Veterans
General Hospital and National Yang-Ming University School of Medicine,
Taipei, Taiwan, Republic of China.
OBJECTIVES: Unusually high incidences of upper urinary tract urothelial
carcinoma (UUT-UC) have been reported from the endemic area for
"blackfoot disease" of southern Taiwan, and the arsenic-contaminated
water was considered to be the reason for this prevalence. In this
study, we determined the ratio of UC in different locations, the
difference in clinical profiles for UUT-UC and urinary-bladder
urothelial carcinoma (UB-UC), and the influence of tumor location on
survival in a medical center of northern Taiwan. METHODS: A total of 535
patients with pathologically proven UC were reviewed retrospectively in
this study, and clinical data were recorded from pathologic and chart
reviews. Statistical analyses to determine the association between tumor
location and clinical variables, and stratified survival analyses to
determine the effect of tumor location on survival were performed.
RESULTS: The incidence of UUT-UC was relatively high (the ratio of renal
pelvis/ureter/urinary bladder was 1:2.08:6.72), even though most of the
patients did not reside in the endemic "blackfoot disease" area. Young
age, female sex, higher T stage, and elevated pretreatment serum lactate
dehydrogenase and creatinine level were significantly associated with
UUT-UC after multivariate logistic regression analysis. Tumor location
influenced survival in patients with early-stage disease or favorable
prognostic factors. CONCLUSIONS: Factors other than arsenic water
contamination may contribute to the unusually high incidence of UUT-UC
in the non-"blackfoot disease" area in Taiwan. UUT-UC carried a more
aggressively clinical behavior than UB-UC; tumor location influences
patient survival markedly in patients with early-stage disease or
favorable prognostic factors.
7
UI - 11992925
AU - Shalev M; Mistry S; Kernen K; Miles BJ
TI -
Squamous cell carcinoma in a female urethral diverticulum.
SO - Urology 2002 May;59(5):773
AD - Department of Urology, Meir General Hospital, Kfar-Saba, Israel.
A 38-year-old woman was found to have a squamous cell carcinoma in a
urethral diverticulum after a simple diverticulectomy. The
aggressiveness of this histologic subtype of carcinoma, along with this
patient's long life expectancy, supported the choice of aggressive
therapy. Only nine other cases have been reported. A brief review of the
published reports on the presentation, diagnosis, options for treatment,
and outcomes is included.
The above citations and abstracts reflect those newly added to CANCERLIT for the month and topic listed in the title. The citations have been retrieved from CANCERLIT using a predefined search strategy of indexed subject terms. Although the search strategy has been refined as best as possible, citations may appear that are not directly related to the topic, and occasionally relevant references may be omitted.
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