Joanne Wolfe, Holcombe E. Grier, Neil Klar, et al.
Abramson Cancer Center of the University of Pennsylvania
Last Modified: November 1, 2001
Reviewers: Li Liu, MD
Source: The New England Journal of Medicine, volume 342, 326-333, (February) 2000
Over the past 30 years, cure rates have increased dramatically for a number of pediatric malignancies because of scientific and technological advances, the advent of specialized pediatric cancer centers for treatment, and the efforts of cooperative group studies. However, improvements in the management of care at the end of life in children with cancer have not kept pace with these clinical advances directed at a cure. In this study, the researchers reported the results of a survey of parents of children who had died of cancer between 1990 and 1997.
A total of 103 parents of children who had died from cancer were interviewed and the medical records were reviewed.
During their last month of life, most children with cancer suffered a great deal from symptoms that might be relieved by simple treatments. The push for a cure should not eliminate the attention of controlling symptoms, some of which may be induced by aggressive treatment. A multidisciplinary approach may be best. This should be flexible enough to provide support of both children whose disease can be cured and those for whom a cure is not yet possible.
Feb 28, 2015 - Patients with advanced cancer who watch a video with end-of-life options after a verbal description of those options are more likely to prefer symptom relief and avoid life-prolonging care such as cardiopulmonary resuscitation compared with patients who only receive the verbal description, according to a study published online Nov. 30 in the Journal of Clinical Oncology.