Treatment Related

An open label study of oral transmucosal fentanyl citrate (OFTC) for the treatment of breakthrough cancer pain Authors: Fine, PG, Marcus M, De Boer AJ, Van der Oord B Source: Pain, 45; 149-153, 1991 Background The majority of cancer patients experience pain during the course of their disease Even when analgesic therapy is initiated, up to 1/3 of...
Breakthrough pain: definition, prevalence and characteristics Authors: Portenoy RK and Hagen NA Source: Pain, 41 (1990) 273-281 Background Pain is likely the most prominent symptom affecting cancer patients' quality of life A majority of patients will have not only a baseline amount of pain, but...
Dexamethasone Alone or in Combination with Ondansetron for the Prevention of Delayed Nausea and Vomiting Induced by Chemotherapy Reviewers: Li Liu, MDSource: The New England Journal of Medicine, volume 342, 1554-1559, (May) 2000IntroductionNausea and vomiting are among the most distressing side effects of chemotherapy for cancer, but the best way to prevent these symptoms is...
Diagnostic Testing Following Fecal Occult Blood Screening in the Elderly Reviewers: Li Liu, MD Source: Journal of the National Cancer Institute, 91:1641-1646, October 1999.BackgroundColorectal cancer is the third most common cancer killer of American men and women. The U.S. Preventive Services Task Force has endorsed...
Effect of Intracoronary (gamma)-Radiation Therapy on In-Stent Restenosis: An Intravascular Ultrasound Analysis from the Gamma-1 Study Reviewers: Li Liu, MD Source: Circulation, volume 102: 2915-2918, (December) 2000Précis: Intracoronary gamma-radiation therapy prevents in-stent restenosisIntroductionDespite its wide acceptance, coronary angioplasty is limited by rates of...
Evaluating the Financial Impact of Clinical Trials in Oncology: Results From a Pilot Study From the Association of American Cancer Institutes/Northwestern University Clinical Trials Costs and Charges Project Reviewers: Li Liu, MD Source: Journal of Clinical Oncology, Volume 18:2805-2810, (August) 2000.Précis: Clinical trials no longer cost more than standard care for cancer patientsIntroductionIt is not known whether the treatment regimens...
Long-Term Safety of Oral Transmucosal Fentanyl Citrate for Breakthrough Cancer Pain Authors: Payne R, Coluzzi P, Hart L, et al. Source: Journal of Pain and Symptom Management, Vol 22 (1), 575-583, 2001 Background Treatment of pain is very often an important part of a cancer treatment regimen Standard pain treatment...
Management of Breakthrough Pain Due to Cancer Author: Simmonds MA Source: Oncology 13(8), 1999, 1103-8 Scientific Implications The following is an excellent review of breakthrough pain in cancer patients. Breakthrough pains have a rapid onset and severe intensity with a short duration....
Once-Weekly Dosing of Epoetin-α Increases Hemoglobin and Improves Quality of Life in Anemic Cancer Patients Receiving Radiation Therapy Either Concomitantly or Sequentially with Chemotherapy Authors: Shasha D, George MJ, Harrison LB Source: Cancer, 2003;98:1072-9 Background Anemia is very common in cancer patients, whether it results from radiation therapy, chemotherapy, or the disease itself Anemia often causes the symptom of...
Oral Transmucosal Fentanyl Citrate: Randomized, Double-Blinded, Placebo-Controlled Trial for Treatment of Breakthrough Pain in Cancer Patients Authors: Farrar JT, Cleary J, Rauck R, Busch M, Nordbrock E Source: JNCI, Vol 90(8), 1998, 611-616 Background The majority of cancer patients will experience pain as a symptom of their disease In addition to persistent pain, many patients...
Radiation Therapy in the Management of Desmoid Tumors Reviewers: John Han-Chih Chang, MDSource: International Journal of Radiation Oncology Biology Physics, December 1998, Volume 42 (Number 5): pages 1007?1014BackgroundDesmoid tumors are aggressive fibromatoses. Local invasiveness characterizes this...
Use of Complementary and Alternative Medicine by Cancer Patients Is Not Associated with Perceived Distress or Poor Compliance with Standard Treatment but with Active Coping Behavior Reviewers: Li Liu, MD Source: Cancer, Volume 89:873-880, (August) 2000.Précis: Interest in complementary medicine a sign of coping in cancer patientsIntroductionComplementary and alternative medicine (CAM) is used by more than one third of...