Sparing gynecologic organs appears to result in good oncologic outcomes, voiding function

-- Monica Smith

Thursday, June 10, 2010 (Last Updated: 06/11/2010)

THURSDAY, June 10 (HealthDay News) -- Gynecologic organ sparing procedures for the surgical treatment of bladder cancer appear to be feasible, with acceptable oncologic outcomes and voiding function, according to research published in the June issue of Urology.

Takuya Koie, M.D., of Hirosaki University in Japan, and colleagues studied data on 30 female bladder cancer patients who underwent radical cystectomy and U-shaped ileal neobladder substitution to determine oncologic outcomes and voiding capabilities.

During the median follow-up of 35.7 months, six patients died, one of whom had a local recurrence and five of whom had distant metastasis. The researchers found that maximum neobladder pressure improved significantly from three months to 12 months following the procedure, as did maximal urethral closure pressure. The capacity of the ileal neobladder also increased over that time, from 204 mL to 311 mL. None of the patients required catheterization to deal with residual urine, and 80 percent of the patients stayed dry night and day.

"Orthotopic neobladder reconstruction with preservation of gynecologic organs is feasible for female bladder cancer patients. Although the follow-up period was not long, the present technique provided acceptable oncological outcome and voiding function," the authors write.

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Specialties Hematology & Oncology
OBGYN & Women's Health

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