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But does not completely offset risk conferred by family history of late-onset breast cancer

-- Eric Metcalf

Wednesday, October 13, 2010 (Last Updated: 10/14/2010)

WEDNESDAY, Oct. 13 (HealthDay News) -- Following American Cancer Society (ACS) guidelines for physical activity, alcohol consumption, and body weight provides similar benefits for postmenopausal women with and without a family history of later-onset breast cancer (FHLBC), according to research published online Oct. 12 in Breast Cancer Research.

Robert Gramling, M.D., D.Sc., of the University of Rochester in New York, and colleagues analyzed data from 85,644 postmenopausal women in the Women's Health Initiative Observational Study who were followed for a mean 5.4 years. None had a family history of early-onset breast cancer. Women were assessed for adherence to three ACS recommendations for breast cancer prevention: at least 20 minutes of exercise at least five days weekly, a normal body weight, and no more than one alcoholic beverage consumed daily.

The rates of invasive breast cancer in women with an FHLBC who adhered to all or none of the behaviors were 5.94 and 6.97 per 1,000 woman-years, respectively. The rates in women without an FHLBC who adhered to all or none were 3.51 and 4.67 per 1,000 woman-years, respectively.

"Given the growing societal awareness of, and distress about, the risk of heritable breast cancer, understanding the actions that women can take to ameliorate this risk is both timely and essential. This study suggests to both public health and office-based clinicians that adherence to the ACS guidelines benefits women with or without an FHLBC but does not function to reduce FHLBC-attributable risk," the authors conclude.

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Specialties Family Practice
Internal Medicine
OBGYN & Women's Health
Hematology & Oncology

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