Wednesday, January 5, 2011 (Last Updated: 01/06/2011)
WEDNESDAY, Jan. 5 (HealthDay News) -- Among men with prostate cancer (PCa), physical activity appears to be associated with lower overall mortality risk and a lower risk of PCa mortality, according to a study published online Jan. 4 in the Journal of Clinical Oncology.
Stacey A. Kenfield, of the Harvard School of Public Health in Boston, and colleagues evaluated physical activity in relation to overall and PCa mortality in 2,705 participants in the Health Professionals Follow-Up Study who were diagnosed with nonmetastatic PCa observed between 1990 and 2008.
The investigators documented 548 deaths among men who lived at least four years after their post-diagnosis physical activity assessment, 20 percent of which were a result of PCa. The investigators also found that men who were physically active had a lower risk of all-cause mortality and PCa mortality, with both non-vigorous activity and vigorous activity associated with significantly lower overall mortality. Compared to men who walked for shorter durations at an easy pace, men who walked at least 90 minutes per week at a normal to very brisk pace had a 46 percent lower risk of all-cause mortality. Those who got at least three hours weekly of vigorous exercise had a 49 percent lower risk of all-cause mortality. Compared with men with less than one hour per week of vigorous activity, men with at least three hours per week of vigorous activity had a 61 percent lower risk of PCa death.
"A modest amount of vigorous activity such as biking, tennis, jogging, or swimming for ≥3 hours a week may substantially improve PCa-specific survival," the authors write.
Hematology & Oncology
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