Monday, February 21, 2011 (Last Updated: 02/22/2011)
MONDAY, Feb. 21 (HealthDay News) -- Balloon kyphoplasty appears to be a safe and effective means for reducing pain and improving function in cancer patients with vertebral compression fractures (VCFs), according to research published online Feb. 17 in The Lancet Oncology.
James Berenson, M.D., of the Institute for Myeloma and Bone Cancer Research in West Hollywood, Calif., and colleagues randomized 134 cancer patients with one to three painful VCFs to kyphoplasty or non-surgical management (control group) to assess the safety and efficacy of the surgical treatment in this patient population.
The researchers found that the treatment group experienced a change in mean disability score from 17.6 at baseline to 9.1 at one month; whereas, the control group did not experience a statistically significant change. Adverse events were similar between the two groups. One patient in the kyphoplasty group experienced a new VCF, which was thought to be device-related.
"For painful VCFs in patients with cancer, kyphoplasty is an effective and safe treatment that rapidly reduces pain and improves function," the authors write.
The study was funded by Medtronic Spine LLC. Several authors disclosed financial relationships with Medtronic and/or other medical device companies.
Hematology & Oncology
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