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In first five years after manifestation of erectile dysfunction more men die of oncological causes

Friday, April 8, 2011 (Last Updated: 04/11/2011)

FRIDAY, April 8 (HealthDay News) -- The risk of mortality due to cardiovascular causes increases in men with erectile dysfunction (ED); however, in the first five years after ED manifestation, there is a higher proportion of deaths due to oncological causes, according to a study published online March 22 in The Journal of Sexual Medicine.

Kew-Kim Chew, M.B.B.S., Ph.D., from the Keogh Institute for Medical Research in Perth, Australia, and colleagues examined the risk of cardiovascular mortality and other causes of death in 2,318 men with ED. Using death registries and hospital morbidity data, deaths from cardiovascular causes were measured as a proportion of all deaths in men with ED, and were compared with a reference male population without ED.

The researchers found that, compared with the reference population, the risk of cardiovascular mortality was higher in men with ED (standardized mortality rate ratio, 2.2). Increased cardiovascular mortality risk was seen in men with cardiovascular disease prior to ED and in those with a history of hospital admissions for cardiovascular events. On average, there was a 10-year interval from the first manifestation of ED to cardiovascular death. In the first five years after the ED manifestation, there were more deaths from oncological causes than cardiovascular causes (25 versus 10.8 percent).

"The majority of deaths among men with ED were from non-cardiovascular causes. There were almost as many deaths from oncological as from cardiovascular causes, and a higher proportion of deaths from oncological causes occurred sooner subsequent to the first manifestation of ED," the authors write.

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Specialties Hematology & Oncology
Family Practice
Internal Medicine

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