Cancer News
OncoLink Cancer News - HealthDay


PSA Test Has Cut Metastatic Prostate Cancer at Presentation

Monday, July 30, 2012 (Last Updated: 07/31/2012)

MONDAY, July 30 (HealthDay News) -- If incidence rates for the pre-prostate-specific antigen (PSA) testing era (1983 to 1985) were present in the modern U.S. population, three times the number of men would have been expected to present with metastatic (M1) prostate cancer (PC) than the actual number observed in 2008, according to a study published online July 30 in Cancer.

Emil Scosyrev, Ph.D., from the University of Rochester Medical Center in New York, and colleagues estimated the total number of patients who would be expected to present with M1 PC in the modern U.S. population in a given year if the annual incidence rates of M1 PC were the same as the rates before PSA testing. The total number of men who presented in 2008 in the Surveillance, Epidemiology, and End Results nine registries area was computed, and the number of cases expected to occur in the absence of PSA testing was estimated.

The researchers found that, in 2008, the observed and expected numbers presenting with M1 PC were 739 and 2,277, respectively, with a 3.1 expected-to-observed ratio. Application of this ratio to the total U.S population in 2008 would have resulted in approximately 25,000 men presenting with M1 PC, compared with the actual observed number of approximately 8,000 men.

"We believe that these estimates must be taken into consideration (bearing in mind the limitations of observational data) when public health policy-level recommendations are made regarding PSA screening," the authors conclude.

Abstract
Full Text (subscription or payment may be required)

Specialties Hematology & Oncology
Urology
Nursing
Nephrology
Pathology

Copyright © 2012 HealthDay. All rights reserved.


I Wish You Knew

Pain management in cancer care - are patients getting what they need?

View More







OncoLink OncoPilot

Facing a new cancer diagnosis or changing the course of your current treatment? Let our cancer nurses help you through!

Learn More