Monday, May 6, 2013 (Last Updated: 05/07/2013)MONDAY, May 6 (HealthDay News) -- The incidence of testicular germ cell tumors (TGCT) increased from 1992 to 2009, especially among Hispanic men, according to research presented at the annual meeting of the American Urological Association, held from May 4 to 8 in San Diego.
Manas Nigam, from the University of Chicago Pritzker School of Medicine, and colleagues examined trends in incidence of TGCT by race, ethnicity, and tumor characteristics from 1992 to 2009 using data extracted from the Surveillance, Epidemiology, and End Results-13 registry.
The researchers found that from 1992 to 2009 there was a significant annual percentage change (1.1 percent) in the incidence of TGCT among U.S. males over the age of 15 years. The rates of TGCT were highest for non-Hispanic white men and lowest for non-Hispanic black men. Incidence rates increased significantly for non-Hispanic white men (1.2 percent), and more prominent increases were observed for Hispanic men, especially from 2002 to 2009 (5.6 percent). The incidence of localized TGCTs and metastatic TGCTs increased significantly (1.21 and 1.43 percent, respectively). Non-Hispanic white men experienced increased incidence in localized tumors (1.56 percent), while for Hispanic men, increases were noted in localized (2.6 percent), regionalized (16.5 percent from 2002 to 2009), and distant (2.6 percent) tumors.
"More research is needed to shed light on why the incidence is up nationwide and if any environmental factors or comorbidities impact disease formation," Jeff Holzbeierlein, M.D., from the University of Kansas Medical Center in Kansas City, said in a statement. "These new data confirm Hispanic Americans should speak with their doctor about risk factors and be even more vigilant with their testicular health."
Hematology & Oncology