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December 2013 Briefing - Hematology & Oncology

Thursday, January 2, 2014 (Last Updated: 01/03/2014)

Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for December 2013. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Troubled Launch of ACA Tops Health News for 2013

TUESDAY, Dec. 31, 2013 (HealthDay News) -- As 2013 nears to a close, the year's top health news story -- the fumbled debut of the Affordable Care Act continues to grab headlines. President Barack Obama, in November, said he was "sorry" to hear that some Americans were being dropped from their health plans due to the advent of reforms -- even though he had repeatedly promised that this would not happen.

CDC: More Than One in 10 Kids Diagnosed With ADHD
FDA Urges Tighter Controls on Certain Prescription Painkillers
CDC: Evocative Campaign Motivates Smokers to Quit
Lower Microbial Diversity for Infants Who Develop Colic
Low Gut Bacterial Richness Linked to Obesity
Donor Fecal Infusion Effective for C. difficile Infection
Full Article - 2013 Top Health News

Acupuncture Improves Breast Cancer Treatment Symptoms

MONDAY, Dec. 30, 2013 (HealthDay News) -- For women with breast cancer receiving aromatase inhibitors (AIs), real acupuncture (RA) and sham acupuncture (SA) seem to improve patient-reported outcomes, according to a study published online Dec. 23 in Cancer.

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USPSTF Recommends Lung CA Screening for High-Risk Adults

MONDAY, Dec. 30, 2013 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends that high-risk asymptomatic adults aged 55 to 80 years should undergo low-dose computed tomography (CT) screening for lung cancer. This recommendation statement is based on the results of a modeling study published online Dec. 31 in the Annals of Internal Medicine.

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Extra Steps Urged for Regulating Compounding Pharmacies

MONDAY, Dec. 30, 2013 (HealthDay News) -- Additional steps are needed for regulating compounding pharmacies, according to a perspective piece published online Dec. 25 in the New England Journal of Medicine.

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Smoking Bans Linked to Improvement in Tobacco Use

MONDAY, Dec. 30, 2013 (HealthDay News) -- Smoking bans in the home and city/town are significantly associated with smoking reduction and making a quit attempt, according to a study published online Nov. 26 in Preventive Medicine.

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Uncertainty Noted in Seemingly Stable Medical Liability Climate

MONDAY, Dec. 30, 2013 (HealthDay News) -- Although the medical liability climate seems stable, the impact of health care reform on the market is uncertain, according to an article based on two reports published by the American Medical Association (AMA).

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Surge in Federal Health Insurance Exchange Enrollments

MONDAY, Dec. 30, 2013 (HealthDay News) -- More than 1.1 million people enrolled in a qualified health plan through the federally operated marketplace, or exchange, from Oct. 1 through Dec. 24, government officials said Sunday. More than 975,000 of those enrollments came in December, Marilyn Tavenner, administrator for the Centers for Medicare & Medicaid Services, said in a blog post.

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AMA IDs Five Issues Relating to Progress in SGR Repeal

FRIDAY, Dec. 27, 2013 (HealthDay News) -- The implications of progress toward repeal of the Medicare sustained growth rate (SGR) formula are discussed in a report published by the American Medical Association (AMA).

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Changes in Pain Noted for Many Ambulatory Cancer Patients

FRIDAY, Dec. 27, 2013 (HealthDay News) -- For ambulatory patients with solid tumors, pain is prevalent and changes over time, according to a study published online Dec. 23 in the Journal of Clinical Oncology.

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Impact of Planned Medicaid Expansion Discussed

THURSDAY, Dec. 26, 2013 (HealthDay News) -- The planned expansion of Medicaid will offer benefits to those in participating states, according to an article published online Dec. 24 in the Annals of Internal Medicine.

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ACA Success Hinges on Young Adult Enrollment

THURSDAY, Dec. 26, 2013 (HealthDay News) -- Enrollment of young adults is a crucial component of the viability of the Affordable Care Act (ACA), according to a health policy brief published Dec. 16 in Health Affairs.

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Physician Pay Increasingly Tied to Quality Metrics

THURSDAY, Dec. 26, 2013 (HealthDay News) -- Physician groups are increasingly incorporating quality metrics into their internal reimbursement structure, according to an article published Nov. 25 in Medical Economics.

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Toxic Employees Are Damaging to Medical Practices

THURSDAY, Dec. 26, 2013 (HealthDay News) -- Toxic behavior can harm medical practices and should not be tolerated, according to an article published Dec. 10 in Medical Economics.

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HPV 6, 11, 42/Combo Detection Doesn't ID CIN 2+, 3+ Risk

THURSDAY, Dec. 26, 2013 (HealthDay News) -- Detection of human papillomavirus (HPV) 6, 11, 42 or combination infections does not identify increased three-year risk of cervical precancer, according to a study published in the January issue of Obstetrics & Gynecology.

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FDA Approves Tretten for Genetic Clotting Disorder

MONDAY, Dec. 23, 2013 (HealthDay News) -- Tretten (coagulation factor XIII A-Subunit recombinant) has been approved by the U.S. Food and Drug Administration to treat a very rare blood clotting disorder called congenital Factor XIII A-Subunit deficiency.

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USPSTF Supports Counseling, BRCA Tests for At-Risk Women

MONDAY, Dec. 23, 2013 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends that women who are identified as being at risk for BRCA mutations be offered counseling and genetic testing, according to a final recommendation statement published online Dec. 24 in the Annals of Internal Medicine.

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Public Tends to Follow Celebrities Even on Medical Issues

MONDAY, Dec. 23, 2013 (HealthDay News) -- Celebrities have credibility as sources of medical advice, even if they are ill-informed or are spreading potentially harmful information, according to research published online Dec. 17 in BMJ.

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Free Preventive Services for >25 Million Medicare Beneficiaries

MONDAY, Dec. 23, 2013 (HealthDay News) -- As a result of the Affordable Care Act, during the first 11 months of 2013, more than 25.4 million people covered by Original Medicare received at least one preventive service at no cost, according to a report from the Centers for Medicare & Medicaid Services (CMS).

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New Rule May Exempt Many From Health Plan Penalty

FRIDAY, Dec. 20, 2013 (HealthDay News) -- Consumers whose individual health insurance policies have been cancelled for failing to meet the minimum requirements of the Affordable Care Act may now apply for a "hardship exemption," Obama administration officials announced late Thursday.

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High Patient Satisfaction With Patient-Centered Medical Homes

FRIDAY, Dec. 20, 2013 (HealthDay News) -- A significant majority of patients report experiencing a high quality of care at federally-supported health centers, according to a study published in the November/December issue of the Annals of Family Medicine.

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Tomato-Based Diet Ups Adiponectin Level in Older Women

FRIDAY, Dec. 20, 2013 (HealthDay News) -- In postmenopausal women at increased risk of breast cancer, consumption of a tomato-based diet is associated with increased adiponectin concentration, according to a study published online Dec. 18 in the Journal of Endocrinology & Metabolism.

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Docs Must Help Patients Take Responsibility for Medical Costs

FRIDAY, Dec. 20, 2013 (HealthDay News) -- Given that increasing numbers of patients have high-deductible health insurance, doctors and practice staff need to help patients assume financial responsibility for costs relating to medical services and procedures, according to an article published Dec. 10 in Medical Economics.

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Role of E-Cigarettes in Eliminating Tobacco Use Discussed

THURSDAY, Dec. 19, 2013 (HealthDay News) -- The public health issues relating to electronic cigarettes (e-cigarettes) and their role in eliminating tobacco use are discussed in a perspective piece published online Dec. 18 in the New England Journal of Medicine.

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Physicians Must Be Proactive in Risk Management

THURSDAY, Dec. 19, 2013 (HealthDay News) -- Risk is inherent in the practice of medicine, but physicians can take steps to prevent patient injury and avoid lawsuits, according to an article published Dec. 10 in Medical Economics.

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Most Oncologists Experience Chemotherapy Drug Shortages

WEDNESDAY, Dec. 18, 2013 (HealthDay News) -- More than 80 percent of oncologists report being unable to prescribe their preferred chemotherapy agent due to shortages, according to a letter to the editor published in the Dec. 19 issue of the New England Journal of Medicine.

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CDC Highlights Achievements of 2013, Goals for 2014

WEDNESDAY, Dec. 18, 2013 (HealthDay News) -- The top five gains made in improving health security at home and around the world in 2013, and the top five areas for improvement in 2014 have been highlighted in an end-of-year report from the U.S. Centers for Disease Control and Prevention.

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Web-Based Tool Cuts Cancer Symptom Distress

WEDNESDAY, Dec. 18, 2013 (HealthDay News) -- A web-based, self-report assessment and educational intervention is beneficial for reducing symptom distress during cancer therapy, according to a study published online Dec. 16 in the Journal of Clinical Oncology.

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Few Residency Programs Teach Cost-Conscious Medicine

WEDNESDAY, Dec. 18, 2013 (HealthDay News) -- Few residency programs have a formal cost-conscious care curriculum, according to a research letter published online Dec. 16 in JAMA Internal Medicine.

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Funding for Medical Communication Firms Analyzed

TUESDAY, Dec. 17, 2013 (HealthDay News) -- Medical communication companies (MCCs), responsible for medical education programs, may receive substantial financial support from pharmaceutical and medical device companies, according to research published in the Dec. 18 issue of the Journal of the American Medical Association.

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GlaxoSmithKline to End Payments to Prescribing Doctors

TUESDAY, Dec. 17, 2013 (HealthDay News) -- GlaxoSmithKline (GSK) says it will stop paying doctors to market its drugs at conferences and will no longer reward sales agents whose physician customers write the most prescriptions. Monday's announcement is apparently a first for a major drug company. But other companies may be considering similar moves, The New York Times reported.

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Neuraxial + General Anesthesia May Up Prostate CA Outcomes

TUESDAY, Dec. 17, 2013 (HealthDay News) -- Supplementing general anesthesia (GA) with neuraxial anesthesia during prostate cancer surgery is associated with improved oncological outcomes compared with GA alone, according to a study published online Dec. 16 in the British Journal of Anaesthesia.

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Many Physicians Will Stop Practicing Due to ACA

TUESDAY, Dec. 17, 2013 (HealthDay News) -- About half of physicians say that they plan to practice medicine for a shorter time or leave as soon as feasibly possible due to the Affordable Care Act (ACA), according to an article published Nov. 29 in Medical Economics.

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FDA Questions Effectiveness, Safety of Antibacterial Soap

TUESDAY, Dec. 17, 2013 (HealthDay News) -- The U.S. Food and Drug Administration has issued a proposed rule requiring antibacterial soap manufacturers to demonstrate that their products are both effective at preventing illness and safe for long-term daily use.

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Physician Access Challenges Up for Those With Public Insurance

TUESDAY, Dec. 17, 2013 (HealthDay News) -- Adverse experiences with physician availability are more likely among those with public insurance, and almost 15 percent of people in the United States were uninsured in the first half of 2013, according to two December data briefs issued by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

Report - Gindi
Report - Martinez and Cohen

Bills for SGR Repeal Pass Senate, House Committees

MONDAY, Dec. 16, 2013 (HealthDay News) -- The U.S. House Ways and Means Committee and the U.S. Senate Finance Committee have passed their versions of the bill to repeal Medicare's failed sustainable growth rate (SGR) formula, according to a report from the American Medical Association (AMA).

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Comorbidity Strongly Influences Survival in Cancer Patients

MONDAY, Dec. 16, 2013 (HealthDay News) -- Death rates from cancer continue to decline in the United States, but the presence of comorbidity can be an important influence on overall survival, according to a report published online Dec. 16 in Cancer.

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Word of Mouth Still Tops Ways People Find Physicians

MONDAY, Dec. 16, 2013 (HealthDay News) -- Roughly three-quarters of young adults use personal recommendations to select a physician, according to an article published in Medical Economics.

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Medicare's Graduate Medical Education Spending Imbalanced

MONDAY, Dec. 16, 2013 (HealthDay News) -- There is an "imbalance" in how Medicare distributes its $10 billion a year for graduate medical education (GME), according to a study published in the November issue of Health Affairs.

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Determinants of Patient Loyalty to Provider Identified

MONDAY, Dec. 16, 2013 (HealthDay News) -- Determinants of patient loyalty have been identified and include confidence in care provider and coordination of care, according to a report published by Press Ganey.

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New Rule Tweaks Affordable Care Act Deadline

FRIDAY, Dec. 13, 2013 (HealthDay News) -- The Obama administration is taking steps to prevent consumers who buy health plans sold through state and federal exchanges from experiencing any gap in coverage this January. Under new rules, health insurers must accept payment up until Dec. 31 for coverage that begins the following day. Earlier guidance did not establish a payment deadline, allowing insurers to set their own dates. "And we're recommending that insurers extend this deadline further," U.S. Health and Human Services (HHS) Secretary Kathleen Sebelius said during a Thursday news conference to announce the changes.

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Insulin Sensitizers Linked With Reduced Risk of Cancer in Women

FRIDAY, Dec. 13, 2013 (HealthDay News) -- Insulin sensitizers, particularly thiazolidinedione use, may reduce the risk of cancer in female patients with type 2 diabetes, according to research published online Dec. 5 in Diabetes, Obesity and Metabolism.

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Integrated Care Endorsed for Castration-Resistant Prostate CA

FRIDAY, Dec. 13, 2013 (HealthDay News) -- For patients with castration-resistant prostate cancer (CRPC), a therapeutic framework should involve an integrated approach, with joint management by a urologist and medical oncologist, according to an article published online Dec. 9 in Urologic Oncology.

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Study Quantifies Male Dominance in Scientific Production

FRIDAY, Dec. 13, 2013 (HealthDay News) -- Men dominate scientific production worldwide, accounting for a higher percentage of authorships and greater impact, according to research published in the Dec. 12 issue of Nature.

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ASCO Report Highlights Progress Against Cancer in Last Year

FRIDAY, Dec. 13, 2013 (HealthDay News) -- Progress against cancer is described in the ninth annual report of the American Society of Clinical Oncology, published online Dec. 10 in the Journal of Clinical Oncology.

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Injunction Stops Insurer From Dropping Physicians

THURSDAY, Dec. 12, 2013 (HealthDay News) -- United Healthcare has been given a last-minute temporary restraining order preventing it from removing thousands of physicians from its Medicare Advantage networks in Connecticut, according to an article published Dec. 6 in Medical Economics.

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Physician Practices Often Do Not Plan for Future

WEDNESDAY, Dec. 11, 2013 (HealthDay News) -- Most physician practices do not treat their practices as businesses and plan for the future, but they should develop and follow a strategic plan, according to an article published Nov. 10 in Medical Economics.

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Recommendations Issued to Prevent VTE in Maternal Patients

WEDNESDAY, Dec. 11, 2013 (HealthDay News) -- The Physician-Patient Alliance for Health & Safety, the Institute for Healthcare Improvement, and the National Perinatal Association have developed safety recommendations aimed at preventing venous thromboembolism (VTE) in maternal patients.

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CDC: Health Insurance Among Young Increased After ACA

WEDNESDAY, Dec. 11, 2013 (HealthDay News) -- Since the Affordable Care Act extended dependent health coverage to young adults up to 26 years old, the percentage of this age group with private health insurance has increased and the percentage with gaps in insurance coverage has decreased, according to a December data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Baseline Inflammation Tied to Lower PCa Risk on Repeat Biopsy

TUESDAY, Dec. 10, 2013 (HealthDay News) -- Among men with a negative biopsy for prostate cancer (PCa), acute and chronic inflammation at baseline correlate with a lower PCa risk at repeat two-year biopsy, according to a study published online Dec. 9 in Cancer.

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Mortality Significantly Up With Smoking After Cancer Diagnosis

TUESDAY, Dec. 10, 2013 (HealthDay News) -- For Chinese male cancer patients, post-diagnosis smoking is associated with an increased risk of death, according to a study published in the December issue of Cancer Epidemiology, Biomarkers & Prevention.

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Less Exercise Linked With Higher Mortality in Breast Cancer

TUESDAY, Dec. 10, 2013 (HealthDay News) -- In a cohort study of women runners and walkers, less exercise and larger breast cup size were associated with increased mortality from breast cancer, according to research published online Dec. 9 in PLOS ONE.

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Outpatient Docs Report More Burnout Than Inpatient Docs

TUESDAY, Dec. 10, 2013 (HealthDay News) -- Outpatient physicians report more emotional exhaustion than inpatient physicians, according to a review published in the November issue of the Journal of Hospital Medicine.

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Study Quantifies Overdiagnosis With Low-Dose CT for Lung CA

TUESDAY, Dec. 10, 2013 (HealthDay News) -- In lung cancer screening, there is a relative mortality reduction with low-dose computed tomography (LDCT); however, limitations include a high rate of overdiagnosis, according to a study published online Dec. 9 in JAMA Internal Medicine.

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Stage III/IV Melanoma Patients at Risk for New Primaries

MONDAY, Dec. 9, 2013 (HealthDay News) -- Patients with stage III or IV melanoma who have not received treatment with BRAF inhibitors remain at risk for developing new primary melanomas (NPMs), although the incidence rates are lower than those observed in studies of dabrafenib and vemurafenib, according to research published online Dec. 2 in the Journal of Clinical Oncology.

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Health Information Technology May Cut Demand for Physicians

MONDAY, Dec. 9, 2013 (HealthDay News) -- Health information technology (IT) may cut demand for physicians in the future, according to a review published in the November issue of Health Affairs.

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With Looming ACA Uncertainty, Budget Exercise Necessary

MONDAY, Dec. 9, 2013 (HealthDay News) -- Constructing a budget for 2014 is critical for physicians even with the uncertainties surrounding the Affordable Care Act, according to an article published Nov. 10 in Medical Economics.

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CMS Finalizes 2014 Physician Payment Rates, Policies

MONDAY, Dec. 9, 2013 (HealthDay News) -- The final payment rules for 2014 include a proposal to support care management outside the routine office interaction and policies to promote high quality care and efficiency, according to a report from the Centers for Medicare & Medicaid Services (CMS).

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Medical Students Find Mind-Body Regulation Training Helpful

FRIDAY, Dec. 6, 2013 (HealthDay News) -- A practical approach may be used to offer mind-body regulation training to medical students, according to research published in the Fall issue of the Annals of Behavioral Science and Medical Education.

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Pre-Op MRI of Margins Predicts Rectal Cancer Outcomes

FRIDAY, Dec. 6, 2013 (HealthDay News) -- Preoperative high-resolution magnetic resonance imaging (MRI) assessment of circumferential resection margin (CRM) status predicts survival and other disease progression outcomes in patients with rectal cancer, according to a study published online Nov. 25 in the Journal of Clinical Oncology.

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Serum 25(OH)D Marker of Ill Health, Not Causative Agent

FRIDAY, Dec. 6, 2013 (HealthDay News) -- Serum 25-hydroxyvitamin D (25[OH]D) seems to be a marker of ill health and not a causal factor, according to a review published online Dec. 6 in The Lancet Diabetes & Endocrinology.

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Issues Surround Hospital Readmissions Reduction Program

FRIDAY, Dec. 6, 2013 (HealthDay News) -- Concerns surround implementation of the Medicare Hospital Readmissions Reduction Program (HRRP), according to a policy brief published online Nov. 12 in Health Affairs.

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Final Rule Aims to Lower Costs, Simplify Outpatient Payments

FRIDAY, Dec. 6, 2013 (HealthDay News) -- The final hospital outpatient and ambulatory surgical center (ASC) payment rule will give hospitals and ASCs the ability to lower costs, according to a report from the Centers for Medicare & Medicaid Services (CMS).

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Handoff Program Cuts Medical Errors, Adverse Events

THURSDAY, Dec. 5, 2013 (HealthDay News) -- Implementation of a multifaceted handoff program can reduce medical errors and preventable adverse events, according to a study published in the Dec. 4 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Recombinant Factor IX Fc Fusion Protein Cuts Injection Frequency

WEDNESDAY, Dec. 4, 2013 (HealthDay News) -- For patients with severe hemophilia B, a recombinant factor IX Fc fusion protein (rFIXFc) with prolonged half-life can safely reduce the frequency of injections, according to a study published online Dec. 4 in the New England Journal of Medicine.

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Results Mixed for Liberal Transfusions in Heart Disease

WEDNESDAY, Dec. 4, 2013 (HealthDay News) -- The effects of liberal transfusion protocols on outcomes in heart disease patients with anemia are mixed, according to a review published in the Dec. 3 issue of the Annals of Internal Medicine.

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AMA's RUC Committee to Work on Improving Transparency

WEDNESDAY, Dec. 4, 2013 (HealthDay News) -- The 31-member Relative Value Scale Update Committee (RUC) of the American Medical Association will begin publishing minutes, dates and locations of meetings, and votes for individual current procedural codes, according to an article published Nov. 11 in Medical Economics.

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Health Reform in Mass. Didn't Change ICU Utilization

WEDNESDAY, Dec. 4, 2013 (HealthDay News) -- Initiation of health care reform in Massachusetts correlated with a reduction in intensive care unit (ICU) patients without insurance but did not significantly change ICU use or mortality among ICU patients, according to a study published online Nov. 22 in Critical Care Medicine.

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Investment Program Can Cut Global Health Disparities by 2035

WEDNESDAY, Dec. 4, 2013 (HealthDay News) -- Global health disparities could be reduced considerably by 2035 using an investment framework, according to a report published Dec. 3 in The Lancet.

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Low Rate of Malignancy for BI-RADS Category 3 Lesions

WEDNESDAY, Dec. 4, 2013 (HealthDay News) -- A low malignancy rate is observed for Breast Imaging Reporting and Data System (BI-RADS) category 3 breast lesions detected by screening ultrasonography (US), according to research published in the December issue of Radiology.

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Modest Increases in Minority Faculty Seen at Med Schools

TUESDAY, Dec. 3, 2013 (HealthDay News) -- Underrepresented minority faculty made only modest gains in increasing their presence at U.S. medical schools from 2000 to 2010, according to a study published in the Journal of the American Medical Association, a theme issue on medical education.

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Physician Texting While 'Doctoring' May Be Hazardous

TUESDAY, Dec. 3, 2013 (HealthDay News) -- Physician texting while doctoring could be hazardous, according to an ideas and opinions piece published in the Dec. 3 issue of the Annals of Internal Medicine.

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FDA Starts Regulating Compounding Pharmacies

TUESDAY, Dec. 3, 2013 (HealthDay News) -- The U.S. Food and Drug Administration on Monday began the process of regulating compounding pharmacies. Under the Drug Quality and Security Act, signed into law Nov. 27 by President Barack Obama, these pharmacies are being encouraged to register with the FDA. The agency will then classify them as outsourcing pharmacies, enabling them to sell bulk drugs to hospitals and other health care facilities.

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Nurse Navigator Intervention Beneficial in Early Cancer Care

TUESDAY, Dec. 3, 2013 (HealthDay News) -- For patients with early cancer, a nurse navigator intervention can improve patient experience and reduce problems with care, according to a study published online Nov. 25 in the Journal of Clinical Oncology.

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Screening Tools Predict Elderly Cancer Patients' Outcomes

MONDAY, Dec. 2, 2013 (HealthDay News) -- Two geriatric screening tools show effectiveness at predicting functional decline and overall survival (OS) in an older population with cancer, according to a study published online Nov. 25 in the Journal of Clinical Oncology.

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Volunteering Overseas Revives Physicians' Outlooks

MONDAY, Dec. 2, 2013 (HealthDay News) -- Physician volunteer programs can revive doctors' passion for medicine, according to an article published Nov. 11 in Medical Economics.

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Health Insurance Coverage Changes Don't Change Behaviors

MONDAY, Dec. 2, 2013 (HealthDay News) -- Change in health insurance coverage is associated with a change in adherence to preventive care, but is not associated with a change in health behaviors, according to a study published in the November-December issue of the Journal of the American Board of Family Medicine.

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