Friday, June 26, 2009
FRIDAY, June 26 (HealthDay News) -- Overweight and obese patients are more likely than normal-weight patients to have inadequate bowel preparation prior to colonoscopy, which could result in missed mucosal lesions and the need for early repeat colonoscopy, according to a study published in the June issue of Clinical Gastroenterology and Hepatology.
Brian B. Borg, M.D., of the Washington University School of Medicine in St. Louis, and colleagues assessed bowel preparation -- assigned a composite outcome score based on a subjective bowel preparation score, prior recommendation for follow-up colonoscopy due to inadequate bowel preparation, and the endoscopist's confidence in adequate evacuation -- in 1,588 patients.
The researchers found that overweight and obesity independently predicted an inadequate composite outcome score. They found that each unit increase in body mass index was associated with a 2.1 percent increased likelihood of an inadequate composite outcome score.
"The implications of our findings are profound," the authors write. "An abnormally increased body mass index is associated with cancer morbidity and mortality, in addition to the risk of metabolic syndrome and all its implications. Colon cancer has been identified as one of the neoplasms seen more often in obese patients. Because the majority of colon cancers arise from adenomatous colon polyps, proper screening for polyps becomes crucial while performing colonoscopy on these patients."
Diabetes & Endocrinology
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