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February 2014 Briefing - Hematology & Oncology

Monday, March 3, 2014 (Last Updated: 03/04/2014)

Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for February 2014. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Going Live With EHR Leads to Frustrations, Productivity Hit

FRIDAY, Feb. 28, 2014 (HealthDay News) -- Implementing an electronic health record (EHR) system takes excessive physician and staff time and disrupts practice, according to survey results published Feb. 24 in Medical Economics.

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Hospital Size, Market Share Affect Inpatient Care Prices

FRIDAY, Feb. 28, 2014 (HealthDay News) -- Size and market share are the greatest differentiators between hospitals receiving low prices and high prices for inpatient care, according to a study published in the February issue of Health Affairs.

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Stethoscopes Contaminated After Single Physical Exam

FRIDAY, Feb. 28, 2014 (HealthDay News) -- Stethoscopes get contaminated after a single physical exam, with the contamination greater than that seen on most of the physician's dominant hand, barring the fingertips, according to a study published online Feb. 27 in the Mayo Clinic Proceedings.

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Smoking Adversely Impacts Renal Cell Carcinoma Survival

THURSDAY, Feb. 27, 2014 (HealthDay News) -- For patients with clear cell renal cell carcinoma, smoking exposure adversely impacts cancer-specific survival and increases the risk of death from another cause, according to a study published in the March issue of The Journal of Urology.

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Review Examines Incretin-Based Drug, Pancreatic Safety Link

THURSDAY, Feb. 27, 2014 (HealthDay News) -- Incretin-based drugs seem not to have a causal association with pancreatitis or pancreatic cancer, according to research published in the Feb. 27 issue of the New England Journal of Medicine.

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Fertility Concerns Common for Young Women With Breast CA

THURSDAY, Feb. 27, 2014 (HealthDay News) -- Fertility concerns are common among young women with newly diagnosed breast cancer, although only a minority pursue fertility preservation strategies, according to a study published online Feb. 24 in the Journal of Clinical Oncology.

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Hysterectomy and Ovary Removal Linked to Diabetes Development

WEDNESDAY, Feb. 26, 2014 (HealthDay News) -- Postmenopausal women are at higher risk of developing diabetes if they have both a hysterectomy and bilateral oophorectomy, according to a study published in the March issue of Diabetes Care.

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Variation Seen in Blood Transfusion Practices After PCI

WEDNESDAY, Feb. 26, 2014 (HealthDay News) -- For patients undergoing percutaneous coronary intervention (PCI), blood transfusion rates and practices vary among hospitals, and transfusion receipt is associated with adverse coronary outcomes, according to a study published in the Feb. 26 issue of the Journal of the American Medical Association.

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Doctors Pleased With Congress' Medicare Payment Agreement

TUESDAY, Feb. 25, 2014 (HealthDay News) -- Physician groups are expressing optimism over the Congressional agreement to revamp the Medicare physician payment system, according to an article published Feb. 26 in Medical Economics.

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Earlier Ovary Removal Provides Greatest BRCA-Associated Benefit

TUESDAY, Feb. 24, 2014 (HealthDay News) -- Among women with mutations in BRCA1 or BRCA2, oophorectomy reduces the risk of developing ovarian, fallopian tube, or peritoneal cancer by 80 percent and reduces the risk of death by 77 percent, with greater BRCA1 benefit seen with earlier removal, according to a study published online Feb. 24 in the Journal of Clinical Oncology.

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Research Agenda Developed for Teen Antipsychotic Rx Use

TUESDAY, Feb. 25, 2014 (HealthDay News) -- Prioritized research agendas have been developed for antipsychotic use among adolescents and young adults and for the management of ductal carcinoma in situ (DCIS), according to two reports published online Feb. 25 in the Annals of Internal Medicine.

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More Than Seven Million Patient Record Breaches in 2013

TUESDAY, Feb. 25, 2014 (HealthDay News) -- The number of patient records breached increased more than 137 percent and affected over seven million records in 2013, according to an annual report published by Redspin.

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Prognosis Worse for Secondary Versus Primary Thyroid Cancers

TUESDAY, Feb. 25, 2014 (HealthDay News) -- Among adolescents and young adults, those who develop thyroid cancer as a secondary malignant neoplasm have decreased overall survival than those with primary thyroid cancer, according to research published online Feb. 24 in Cancer.

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Low Iron Tied to Higher Stroke Risk in Some People

MONDAY, Feb. 24, 2014 (HealthDay News) -- People with defective pulmonary capillary filtration are at higher risk of having an ischemic stroke if they have low iron levels, possibly due to enhanced platelet aggregation, according to a study published online Feb. 19 in PLOS ONE.

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USPSTF: Evidence Lacking for Vitamin Prevention of CVD, CA

MONDAY, Feb. 24, 2014 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) has found that the evidence is insufficient to evaluate the benefits and harms of multivitamins and most single- or paired-nutrient supplements for the prevention of cardiovascular disease and cancer. The Task Force findings have been published in a final recommendation statement available online Feb. 25 in the Annals of Internal Medicine.

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Quality Measures Data Added to Physician Compare Website

MONDAY, Feb. 24, 2014 (HealthDay News) -- Data for quality measures have been added to Physician Compare, the website that helps consumers search for information about physicians, according to a report published by the Centers for Medicare & Medicaid Services (CMS).

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'Epidemic of Diagnosis' Driving Thyroid Cancer Rates Up

MONDAY, Feb. 24, 2014 (HealthDay News) -- The incidence of thyroid cancer increased nearly three-fold from 1975 to 2009, particularly in women, with the increase mainly attributable to papillary thyroid cancer, according to a study published online Feb. 20 in JAMA Otolaryngology-Head & Neck Surgery.

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Repeat Biopsies Up Infection Risk in Prostate Cancer Patients

MONDAY, Feb. 24, 2014 (HealthDay News) -- For men with prostate cancer who are under active surveillance, repeated biopsies are associated with increased risk of infectious complications, according to research published in the March issue of The Journal of Urology.

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FDA to Step Up Oversight of Indian Drug Makers

MONDAY, Feb. 24, 2014 (HealthDay News) -- The U.S. Food and Drug Administration is to increase monitoring of drugs from pharmaceutical companies in India, FDA Commissioner Margaret Hamburg, M.D., said during a Friday afternoon news conference.

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More Older Men Have Skin Exams After Watching Educational Video

FRIDAY, Feb. 21, 2014 (HealthDay News) -- Older men are more likely to have a whole-body skin exam done by their physician if they watch a video on skin self-examination and skin awareness, according to a study published online Feb. 19 in JAMA Dermatology.

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MRI May Be Alternative for Staging Cancer in Young Patients

FRIDAY, Feb. 21, 2014 (HealthDay News) -- A new type of whole-body magnetic resonance imaging (MRI) may allow detection and staging of tumors in children and young adults, without exposure to ionizing radiation, according to research published online Feb. 19 in The Lancet Oncology.

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Concurrent Opioid Prescribing by Multiple Providers Common

THURSDAY, Feb. 20, 2014 (HealthDay News) -- For Medicare beneficiaries, concurrent opioid prescribing is common among those with four or more opioid providers, according to a study published Feb. 19 in BMJ.

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Unfilled Hospital Openings for Doctors Growing, Survey Finds

THURSDAY, Feb. 20, 2014 (HealthDay News) -- The need for hospital physicians is growing, according to an article published Jan. 3 in Medical Economics.

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Breast Reconstructions Up in U.S. Breast Cancer Patients

THURSDAY, Feb. 20, 2014 (HealthDay News) -- The use of breast reconstruction in breast cancer patients undergoing mastectomy has been increasing in the United States, according to research published online Feb. 18 in the Journal of Clinical Oncology.

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Adjuvant Bevacizumab Ups Survival in Cervical Cancer

WEDNESDAY, Feb. 19, 2014 (HealthDay News) -- Adjuvant bevacizumab increases overall survival in cervical cancer and improves progression-free survival in glioblastoma, according to three studies published in the Feb. 20 issue of the New England Journal of Medicine.

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Before Implementation, Full EHR Cost Needs Consideration

WEDNESDAY, Feb. 19, 2014 (HealthDay News) -- From the outset of electronic health record implementation, hospitals and governments need to understand the major cost categories involved and identify the factors that may impact these costs, according to research published online Feb. 12 in the Journal of the American Medical Informatics Association.

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'Talking' Medical Devices, Apps Continue to Evolve

WEDNESDAY, Feb. 19, 2014 (HealthDay News) -- "Talking" medical devices and apps, among other techy health-focused inventions, can help people manage everyday wellness routines, such as taking pills and checking blood sugar levels, as well as dire medical circumstances, say experts.

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Online Ratings Do Affect Patient Choice of Physician

TUESDAY, Feb. 18, 2014 (HealthDay News) -- About two-thirds of the general U.S. population is aware of online physician rating sites, according to a research letter published in the Feb. 19 issue of the Journal of the American Medical Association.

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Compression Device Noninferior to Meds Post-Arthroplasty

TUESDAY, Feb. 18, 2014 (HealthDay News) -- For patients undergoing lower-extremity arthroplasty, a mobile compression device is noninferior to pharmacological protocols for the prevention of venous thromboembolism, according to a study published in the Feb. 5 issue of The Journal of Bone & Joint Surgery.

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Antibody Prevents Thrombosis Without Increasing Bleeding

TUESDAY, Feb. 18, 2014 (HealthDay News) -- A humanized antibody prevents thrombosis without increasing bleeding in extracorporeal circulation in animal models, according to a study published in the Feb. 5 issue of Science Translational Medicine.

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Direct-to-Consumer Genomic Testing Concerns Explored

TUESDAY, Feb. 18, 2014 (HealthDay News) -- Various concerns relate to direct-to-consumer genomic testing, according to an ideas and opinions piece published online Feb. 10 in the Annals of Internal Medicine.

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Physicians More Likely to Be Burned Out Than Non-Doc Peers

TUESDAY, Feb. 18, 2014 (HealthDay News) -- Trainees and early-career physicians are more likely to be burned out than control population samples, according to research published online Jan. 20 in Academic Medicine.

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AAFP: Telemedicine Can Help With Increased Demand for Docs

MONDAY, Feb. 17, 2014 (HealthDay News) -- Telemedicine offers a potential solution to the increased demand for physician-patient interaction, according to a report from a recent forum. The forum was hosted by the Robert Graham Center for Policy Studies in Family Medicine and Primary Care, and the results of the discussion were published by the American Academy of Family Physicians (AAFP).

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Panel of 55 Genes Predicts Breast Cancer Survival

MONDAY, Feb. 17, 2014 (HealthDay News) -- Changes in expression of a panel of 55 genes, linked with tumor suppressor gene SYK, in patients with breast cancer predicts both whether or not the cancer will become invasive and survival, according to a study published online Feb. 11 in PLOS ONE.

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Non-Traditional Office Hours Can Reap Big Financial Benefits

MONDAY, Feb. 17, 2014 (HealthDay News) -- Physicians can reap significant financial benefits by extending their office hours to include non-traditional hours, according to an article published Jan. 8 in Medical Economics.

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People of Color Need Sun Protection to Avoid Skin Cancer

FRIDAY, Feb. 14, 2014 (HealthDay News) -- Although skin cancer is less prevalent among people of color than in whites, sun protection and other preventive measures are essential components of skin care in these populations, according to research published online Jan. 30 in the Journal of the American Academy of Dermatology.

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Low Rates of Recurrence With 'No Ink' As Margin in Breast CA

FRIDAY, Feb. 14, 2014 (HealthDay News) -- Positive margins (ink on invasive carcinoma or ductal carcinoma in situ) are associated with increased risk of ipsilateral breast tumor recurrence (IBTR), according to consensus guidelines published online Feb. 10 in the Journal of Clinical Oncology.

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Bilateral Mastectomy Cuts Mortality for BRCA-Related CA

FRIDAY, Feb. 14, 2014 (HealthDay News) -- Women with BRCA-associated early-stage breast cancer who receive bilateral mastectomy are less likely to die from breast cancer than those who receive a unilateral mastectomy, according to research published Feb. 11 in BMJ.

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Annual Mammography Doesn't Reduce Breast Cancer Mortality

FRIDAY, Feb. 14, 2014 (HealthDay News) -- Annual mammography does not reduce mortality from breast cancer among 40- to 59-year-old women, according to research published Feb. 11 in BMJ.

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Congress Agrees on Legislation to Replace SGR Formula

THURSDAY, Feb. 13, 2014 (HealthDay News) -- Congress has agreed on legislation to repeal the Sustainable Growth Rate (SGR) formula, which will guarantee Medicare providers annual 0.5 percent reimbursement increases as new payment models are introduced, according to an article published Feb. 11 in Medical Economics.

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CMS Extends 2013 Meaningful Use Attestation Deadline

THURSDAY, Feb. 13, 2014 (HealthDay News) -- The Centers for Medicare & Medicaid Services (CMS) have extended another deadline for the Medicare electronic health record (EHR) Incentive Program, according to an article published Feb. 11 in Medical Economics.

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ICD-10 Implementation Likely to Be Financial Disaster

THURSDAY, Feb. 13, 2014 (HealthDay News) -- The American Medical Association (AMA) is continuing its efforts to stop implementation of the International Classification of Diseases, 10th Revision (ICD-10), citing the huge financial burden for physicians.

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Affordable Care Act Enrollment Nears 3.3 Million

THURSDAY, Feb. 13, 2014 (HealthDay News) -- 3.3 million Americans have signed up for health insurance through the state and federal marketplaces created by the Affordable Care Act, the Obama administration announced Wednesday.

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Biopsy-Based Management Improves Melanoma Outcomes

WEDNESDAY, Feb. 12, 2014 (HealthDay News) -- Sentinel-node biopsy-based management of primary cutaneous melanomas is associated with improved long-term outcomes, according to a study published in the Feb. 13 issue of the New England Journal of Medicine.

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FDA Expands Imbruvica Approval to Include CLL

WEDNESDAY, Feb. 12, 2014 (HealthDay News) -- U.S. Food and Drug Administration approval of Imbruvica (ibrutinib) has been expanded to include people with chronic lymphocytic leukemia (CLL) who have tried at least one previous therapy.

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U.S. Officials Target Escalating Drug Overdoses

WEDNESDAY, Feb. 12, 2014 (HealthDay News) -- As deaths from heroin and prescription painkillers mount across the United States, government officials are searching for ways to stem the toll of addiction.

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Adding Signage Improves Smoke-Free Regulation Awareness

WEDNESDAY, Feb. 12, 2014 (HealthDay News) -- Efforts to increase awareness of smoke-free rules, including new signage, seem effective, according to research published online Jan. 30 in the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Guidelines Issued for Managing Hospital Medicine Groups

TUESDAY, Feb. 11, 2014 (HealthDay News) -- A new assessment guide comprising 10 principles has been developed for effective management of hospital medicine groups (HMGs), according to research published in the February issue of the Journal of Hospital Medicine.

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Metformin Use Doesn't Cut Incidence of Bladder Cancer

TUESDAY, Feb. 11, 2014 (HealthDay News) -- For patients with type 2 diabetes, metformin use is not associated with a significantly reduced risk of bladder cancer, according to a study published online Feb. 4 in Diabetes Care.

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Perceived Control Reduces Mortality Risk for Lesser Educated

TUESDAY, Feb. 11, 2014 (HealthDay News) -- Stronger beliefs of control over one's life are associated with reduced risk of mortality among those with lower levels of educational attainment, according to research published online Feb. 3 in in Health Psychology.

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Smoking Ups Risk of ER-Positive Breast Cancer in Women

TUESDAY, Feb. 11, 2014 (HealthDay News) -- Younger women who smoke appear to be at increased risk for developing estrogen receptor (ER)-positive breast cancer, according to research published online Feb. 10 in Cancer.

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Mid-Sized Companies Get Extra Year to Comply With ACA

TUESDAY, Feb. 11, 2014 (HealthDay News) -- Medium-sized companies will have another year before they have to provide employees with health insurance or face tax penalties, the Obama administration announced Monday.

Other Health Highlights: Feb. 10, 2014

Residents Concerned About Lack of Time With Patients

MONDAY, Feb. 10, 2014 (HealthDay News) -- Many U.S. medical residents are concerned about reduced face-time with patients and report that engaging patients in their own care is more challenging than anticipated, according to a report from the American Resident Project, sponsored by ThinkWellPoint.

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President's Panel Calls for More Girls, Boys to Get HPV Vaccine

MONDAY, Feb. 10, 2014 (HealthDay News) -- Too few American girls and boys are getting vaccinated against human papillomavirus (HPV), the President's Cancer Panel reported Monday.

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New Rule Allows Patients to Access Laboratory Test Results

MONDAY, Feb. 10, 2014 (HealthDay News) -- In a final rule relating to the Health Insurance Portability and Accountability Act (HIPAA), a patient or their personal representative can access their completed test reports directly from the laboratory, according to a report from the U.S. Department of Health & Human Services (HHS).

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Ascorbate Exhibits Beneficial Effects in Ovarian Cancer

MONDAY, Feb. 10, 2014 (HealthDay News) -- Intravenous ascorbate (vitamin C) seems beneficial in ovarian cancer, inducing cell death in vitro and reducing chemotherapy-associated toxicity in vivo, according to a study published in the Feb. 5 issue of Science Translational Medicine.

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Obese Men More Likely to Have Colon Polyps

MONDAY, Feb. 10, 2014 (HealthDay News) -- Obese men have a more than six-fold higher likelihood of having multiple colon polyps and tubular adenomas than lean men, according to a study published online Jan. 17 in PLOS ONE.

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Obesity Linked to Worse Prognosis in Oral Tongue SCC

MONDAY, Feb. 10, 2014 (HealthDay News) -- For patients with squamous cell carcinoma (SCC) of the oral tongue, obesity is associated with adverse prognosis and significantly worse disease-specific survival, according to a study published online Jan. 21 in Cancer.

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Gaps Exist in Patient-Centered Quality of CRC Care at VA

FRIDAY, Feb. 7, 2014 (HealthDay News) -- Patient-reported quality assessment measures reveal substantial gaps in patient-centered quality of colorectal cancer care, according to a study published online Feb 3 in the Journal of Clinical Oncology.

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New Technique Ups Detection Rate in Screening Mammography

FRIDAY, Feb. 7, 2014 (HealthDay News) -- Digital mammography screening with a direct radiography (DR) photon-counting system has good diagnostic performance, according to a study published online Feb. 4 in Radiology.

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Daily Aspirin May Guard Against Ovarian Cancer

FRIDAY, Feb. 7, 2014 (HealthDay News) -- Taking aspirin every day might lower a woman's risk of developing ovarian cancer by one-fifth, according to research published in the February issue of the Journal of the National Cancer Institute.

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Personalized Therapy Feasible for Metastatic Breast Cancer

FRIDAY, Feb. 7, 2014 (HealthDay News) -- For patients with metastatic breast cancer, personalization of therapy is feasible, according to a study published online Feb. 7 in The Lancet Oncology.

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Review: Coffee in Pregnancy Tied to Childhood Leukemia Risk

THURSDAY, Feb. 6, 2014 (HealthDay News) -- Maternal coffee consumption during pregnancy is associated with increased risk of childhood acute leukemia (AL), according to a meta-analysis published in the February issue of the American Journal of Obstetrics & Gynecology.

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CLER Pathways to Excellence Document Issued

THURSDAY, Feb. 6, 2014 (HealthDay News) -- The Clinical Learning Environment Review (CLER) Pathways to Excellence document has been released for graduate medical education as a foundation for preparing the physician workforce in patient safety and quality improvement, according to a report from the Accreditation Council for Graduate Medical Education (ACGME).

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Oncologists Report High Career Satisfaction

THURSDAY, Feb. 6, 2014 (HealthDay News) -- Oncologists are overall very satisfied with their careers, according to a study published online Jan. 27 in the Journal of Clinical Oncology.

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Oropharyngeal Squamous Cell Carcinoma Up From 1973 to 2009

THURSDAY, Feb. 6, 2014 (HealthDay News) -- From 1973 to 2009, the incidence of oropharyngeal squamous cell carcinoma (OPSCC) increased in patients younger than 45 years, according to a study published online Jan. 22 in Otolaryngology-Head and Neck Surgery.

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Running Beats Walking for Breast Cancer Survival

THURSDAY, Feb. 6, 2014 (HealthDay News) -- For breast cancer survivors, post-diagnosis running is associated with reduced mortality versus walking, according to a study published online Jan. 27 in the International Journal of Cancer.

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Choosing Wisely Tips Should Prompt Doc-Patient Discussion

WEDNESDAY, Feb. 5, 2014 (HealthDay News) -- The Choosing Wisely recommendations can form a starting point for discussing cost and appropriate use of testing with patients, according to an article from the American Medical Association (AMA).

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ICD-10 Transition May Impact Practice Cash Flow

WEDNESDAY, Feb. 5, 2014 (HealthDay News) -- Physicians and health plans remain unprepared for the disruption that implementation of the International Classification of Diseases, 10th Revision (ICD-10) will bring to their cash flow, according to an article published Jan. 14 in Medical Economics.

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CVS Caremark to Stop Selling Tobacco Products

WEDNESDAY, Feb. 5, 2014 (HealthDay News) -- The national drug store chain CVS Caremark said Wednesday that it's phasing out the sale of tobacco products at its more than 7,600 stores across the United States.

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EHR Use During Patient Visit May Mean Missed Non-Verbal Cues

WEDNESDAY, Feb. 5, 2014 (HealthDay News) -- Patterns of eye gaze change with the use of electronic health records (EHRs), and this influences physician-patient interaction, according to research published in the March issue of the International Journal of Medical Informatics.

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Indoor Tanning Remains Popular, Especially in the Young

WEDNESDAY, Feb. 5, 2014 (HealthDay News) -- Exposure to indoor tanning is common in Western countries, particularly among young persons, according to research published online on Jan. 29 in JAMA Dermatology.

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Patients Are 'Myth'-Informed About Their Risk of Cancer

TUESDAY, Feb. 4, 2014 (HealthDay News) -- Fewer than half of Americans are aware that body weight and physical activity affect cancer risk, according to the results of a survey commissioned by the American Institute for Cancer Research (AICR).

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Biomarker Could Help Predict Survival After Melanoma Tx

TUESDAY, Feb. 4, 2014 (HealthDay News) -- Patients with metastatic melanoma who have high serum levels of vascular endothelial growth factor (VEGF) before treatment with ipilimumab have worse survival than patients with lower VEGF levels, according to a study published in the February issue of Cancer Immunology Research.

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High Overall CRC Diagnostic Accuracy for Home Stool Test

TUESDAY, Feb. 4, 2014 (HealthDay News) -- Fecal immunochemical tests (FITs) have moderate sensitivity, high specificity, and high overall diagnostic accuracy for detecting colorectal cancer (CRC), according to research published in the Feb. 4 issue of the Annals of Internal Medicine.

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First- and Second-Generation Family Hx Adequate in Oncology

TUESDAY, Feb. 4, 2014 (HealthDay News) -- Recommendations relating to the key elements of minimum adequate cancer family history are detailed, although they are often incompletely implemented, according to a recommendation statement and related study published online Feb. 3 in the Journal of Clinical Oncology.

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Abstract - Wood
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Online Medical Records Trump Colleagues As Docs' Info Source

TUESDAY, Feb. 4, 2014 (HealthDay News) -- Online patient medical records are the top source of information for doctors, based on the mean annual exposure, according to the results of a survey conducted by Kantar Media.

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Expressive Writing May Benefit Renal Cancer Patients

MONDAY, Feb. 3, 2014 (HealthDay News) -- For patients with renal cell carcinoma (RCC), expressive writing (EW) may improve cancer-related symptoms and physical functioning, according to a study published online Jan. 27 in the Journal of Clinical Oncology.

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Health Reform Differs Across States: Report

MONDAY, Feb. 3, 2014 (HealthDay News) -- California is one of 10 states that have done the most to roll out provisions of the Affordable Care Act, according to a new Commonwealth Fund report. These states, including Colorado, Connecticut, Hawaii, Maryland, Massachusetts, Minnesota, New York, Oregon, and Vermont, have committed to implementing "the most significant aspects of health reform," the report states.

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