Friday, February 6, 2009
FRIDAY, Feb. 6 (HealthDay News) -- Women who are treated with fertility drugs are not at increased risk of ovarian cancer, regardless of what types of drugs are used, according to the results of a study published online Feb. 5 in BMJ.
Allan Jensen, of the Danish Cancer Society in Copenhagen, Denmark, and colleagues analyzed data on 54,362 women who were treated for infertility at all Danish clinics from 1963 to 1998. The women underwent treatment with four types of fertility drugs -- gonadotrophins, clomifene citrate, human chorionic gonadotrophin, and gonadotrophin-releasing hormone -- and were followed-up at a median age of 47 years. (The median age was 30 years at first evaluation of infertility.)
There were 156 women with invasive epithelial ovarian cancer in the cohort, and researchers found no increased risk of ovarian cancer with use of any of the four types of fertility drugs. There was also no association between all four groups of drugs and number of cycles of use, length of follow-up or parity, the report indicates.
"However, as many of the women in our cohort have not yet reached the usual peak age for ovarian cancer, we will continue to monitor the risk to try to establish a more definite link between use of fertility drugs and risk of ovarian cancer," the authors write.
Diabetes & Endocrinology
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