Cancer News
OncoLink Cancer News - HealthDay

Procedure May Be Helpful in Diagnosing Prostate Cancer

-- Eric Metcalf

Friday, October 2, 2009

FRIDAY, Oct. 2 (HealthDay News) -- Transurethral prostate resection may be a useful addition to prostate biopsy in detecting cancer in men whose prostate-specific antigen (PSA) remains a concern after previous negative biopsies, according to research published in the October issue of the Journal of Urology.

Guillaume Ploussard, M.D., of the Centre Hospitalier Universitaire Henri Mondor in Creteil, France, and colleagues analyzed data from 113 patients who underwent transurethral resection of the prostate (TURP) along with a set of 21-core biopsies. All patients had persistently high or increasing PSA and had undergone at least two sets of extended 21-core negative biopsies.

The researchers found that prostate cancer was found in 27 men. Extended biopsy had an 18.6 percent detection rate, and TURP increased the detection rate by 28.5 percent, which was a significant increase compared to biopsy alone. Most cancers found in samples from TURP or biopsy were clinically significant.

"About a fourth of patients with two extended multi-site negative prostate biopsy sets remained at risk for prostate cancer and tumors undetected at initial procedures were not trivial. Repeating biopsy using general anesthesia increased the detection rate, which was 18.6 percent. The diagnostic yield of TURP was moderate but significant and may provide additional data of clinical importance in select patients. Patients may also benefit from the procedure because of decreased PSA during biological follow-up and better prostate sampling at subsequent biopsy sets," the authors conclude.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Specialties Cardiology
Diabetes & Endocrinology
Internal Medicine
Family Practice

Copyright © 2009 ScoutNews, LLC. All rights reserved.

I Wish You Knew

Pain management in cancer care - are patients getting what they need?

View More

Blogs and Web Chats

OncoLink Blogs give our readers a chance to react to and comment on key cancer news topics and provides a forum for OncoLink Experts and readers to share opinions and learn from each other.

OncoLink OncoPilot

Facing a new cancer diagnosis or changing the course of your current treatment? Let our cancer nurses help you through!

Learn More