Cancer News
OncoLink Cancer News - HealthDay

Racial Disparities in Colon Cancer Mortality Unexplained

-- A. Agrawal, PhD

Tuesday, November 24, 2009

TUESDAY, Nov. 24 (HealthDay News) -- Differences in comorbidities and weight do not explain the higher risk of death in African-Americans with colon cancer compared with Caucasians, according to a study published online Nov. 24 in Cancer.

Robert B. Hines, of the University of Alabama in Birmingham, and colleagues analyzed data from 496 patients (39.2 percent African-American and 60.8 percent Caucasian) who had undergone surgery for a first primary colon cancer.

The researchers found a higher risk of death in African-Americans (hazard ratio, 1.34), in patients due to all-cause mortality (hazard ratio, 1.63), and in underweight patients (hazard ratio, 1.54). Overweight and obese patients had a lower risk of death (hazard ratio, 0.77). Comorbidities primarily affected those with early-stage tumors, while body mass index primarily affected those with advanced tumors. Adjusting for comorbidity and body mass index had little effect on the risk of death in African-Americans.

"Although comorbidity and body mass index had an impact on the survival of patients with colon cancer after surgery, these variables were not contributing factors to the decreased survival observed among African-Americans," the authors conclude.

Full Text (subscription or payment may be required)

Specialties Cardiology
Diabetes & Endocrinology
Internal Medicine
Family Practice

Copyright © 2009 ScoutNews, LLC. All rights reserved.

I Wish You Knew

Importance of funding cancer research

View More

Blogs and Web Chats

OncoLink Blogs give our readers a chance to react to and comment on key cancer news topics and provides a forum for OncoLink Experts and readers to share opinions and learn from each other.

OncoLink OncoPilot

Facing a new cancer diagnosis or changing the course of your current treatment? Let our cancer nurses help you through!

Learn More