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Cancer Treatment Information > Bone Marrow Transplants > News
March 2009
Bone marrow transplant patients fare best with HLA-identical sibling donors
February 2009
Partially matched cord blood a good option for transplantation in children
November 2008
Less toxic bone marrow transplantation can cure sickle cell disease
October 2008
Hyperglycemia tied to infection in bone marrow recipients
September 2008
GVHD reversed by extracorporeal photopheresis-treated cells
June 2008
Inpatient exercise benefits bone marrow transplant patients
May 2008
Acute leukemia not a contraindication for ICU admission
December 2007
Scaled-down chemo regimen seen effective for AML in Down syndrome
SCID patient has leukaemia after UK gene therapy
Gentler chemo helps patients survive lymphoma
November 2007
Captopril may limit radiation-induced kidney damage after BMT
July 2007
Repeat melphalan and stem cells useful in AL amyloidosis
Myeloablative therapy prolongs remission in follicular lymphoma patients
June 2007
Bone marrow transplant reverses severe complications of mevalonic aciduria
March 2007
Low-power laser prevents oral mucositis after stem cell transplant
February 2007
Combination therapy promising against Krabbe's disease
July 2006
Thalidomide boosts multiple myeloma therapy response
June 2006
Bone marrow transplant may reverse skin fibrosis in severe systemic sclerosis
April 2006
Bone marrow transplant shows lasting benefit in heart disease
Rituximab effective against chronic graft-versus-host disease
January 2006
Hematopoietic stem cell transplantation effective for acute leukemia in infants
Fetal exposure to noninherited maternal antigens enhances immune tolerance
Intense bone marrow transplantation protocol not useful for severe MS
December 2005
Cidofovir an option for viral infections in pediatric bone marrow transplant recipients
November 2005
Reduced-intensity transplantation feasible in chronic myeloid leukemia
October 2005
Primed T-cell transfer after stem cell transplant boosts immunity
September 2005
Pulmonary complications of bone marrow transplant commonly undiagnosed
August 2005
Liposomal amphotericin B may be hard on the liver in bone marrow recipients
Muscle strength impaired prior to undergoing HSCT
July 2005
Herpesvirus 8 often spread by bone marrow transplants
June 2005
Intensive therapy no better than CHOP for T-cell non-Hodgkin lymphoma
April 2005
Tumor-targeted, TGF-beta-immune cells destroy prostate cancer in mouse model
March 2005
Targeted gene therapy effective in alpha-mannosidosis
T regulatory cells promote successful bone marrow transplantation in mice
Ethnic factors may affect complication risk after BMT
February 2005
Two partially matched cord blood transplants safe, effective in adults
January 2005
Thyroid dysfunction common after bone marrow transplantation in childhood
December 2004
Trial of oral beclomethasone for GVHD gives mixed results
FDA approves clofarabine for childhood acute lymphoblastic leukemia
Allogenic graft prolongs survival longer than autologous graft for leukemia
New bone marrow transplant strategy curbs GVHD but not anti-tumor activity
Ilex's leukemia drug shows some benefits, FDA panel finds
November 2004
Cord blood provides stem cell grafts for leukemia patients
Stem cell transplant outcomes worse in pediatric leukemia patients
September 2004
New regime reduces thalassemia relapse after BMT
July 2004
Myelodysplastic syndrome risk guides marrow transplant timing
June 2004
Clofarabine promising for relapsed or refractory pediatric acute leukemia
Early second transplant for multiple myeloma may improve outcome
April 2004
Stem cell transplantation restores T-cell immunity in JAK3 deficiency
Host Langerhans cell depletion can prevent skin graft-versus-host disease
Gene expression profiling yields prognostic information for AML patients
March 2004
Although recommended, G-CSF after marrow transplant may raise GVHD risk
November 2003
Non-purged bone marrow transplant improves survival in lymphoma
October 2003
West Nile encephalitis reported in stem cell recipients
August 2003
Regulatory cells suppress GVHD effects of T cells, but allow antitumor activity
July 2003
Candidemia infrequent but serious in breast cancer patients after BMT
Fetal HLA typing could improve treatment of beta thalassaemia
April 2003
Valacyclovir an option to prevent CMV disease after bone marrow transplant
New strategy preserves graft-versus-leukemia response without lethal GVHD
March 2003
T cell trapping prevents GVHD while preserving antitumor response to BMT
Imatinib superior to interferon/cytarabine for CML
January 2003
Transplanted stem cells migrate to brain, differentiate into neurons
December 2002
Platelet count 100 days after BMT is powerful predictor of survival
November 2002
Daunorubicin as effective, less toxic than idarubicin in some childhood AML cases
October 2002
MS patients to undergo stem cell transplants
September 2002
Endocrine dysfunction common in bone marrow recipients
August 2002
Cognitive deficits follow bone marrow transplant in long-term adult survivors
July 2002
Unrelated-donor bone marrow feasible for patients with beta-thalassemia major
Cytokine improves immune function after bone marrow transplantation in mice
Donor lymphocyte infusion helps immune reconstitution after BMT
June 2002
Novel Janus kinase 3 inhibitor improves BMT outcome in animal model
Purging process preserves T cells' antileukemic effects while preventing GVHD
May 2002
Intensified chemotherapy improves acute lymphoblastic leukemia outcome
Unrelated marrow transplant can be effective for ALL in second remission
Hematopoietic recovery, survival associated with CD34 cell dose in BMT
Renal thrombotic microangiopathy may be overlooked in cancer patients
April 2002
Gene therapy appears to cure X-linked severe combined immunodeficiency
Adoptive transfer of hepatitis B core antigen immunity resolves chronic hepatitis B
March 2002
Mismatched transplant cures sickle cell disease in mouse model
Cord blood stem cell transplant provides long-term immune reconstitution
Fertility may return after autologous stem cell transplantation
Alloreactive NK cells may enhance success of bone marrow transplants
Peripheral stem cell better with bone marrow transplantation for CML
Transplanted circulating stem cells differentiate into hepatocytes, epithelial cells
February 2002
Bone marrow transplantation inhibits osteoblastic differentiation of stromal cells
Bone marrow transplantation inhibits osteoblastic differentiation of stromal cells
Interferon-alpha and cytarabine useful in pediatric chronic myeloid leukemia
Interferon-alpha and cytarabine useful in pediatric chronic myeloid leukemia
New definitions of opportunistic invasive fungal infections
December 2001
Immunity recovers to nearly normal 20 years after bone marrow transplant
Non-serologic HLA mismatches do not increase stem cell graft failure risk
Prior interferon therapy for CML has no effect on stem cell transplant outcome
Patients' sense of well-being diminished following autologous BMT
Allogeneic BMT may be optimal for refractory Hodgkin's lymphoma
November 2001
Circulating stem cells implicated in bone marrow engraftment
T-cell lymphoma transmitted by allogeneic bone marrow transplantation
G-CSF priming improves engraftment and reduces GVHD after allogeneic BMT
October 2001
Early postnatal BMT preferable to in utero transplantation for SCID
Cytokine genotype influences graft-versus-host disease risk
High-dose cyclophosphamide shows promise as aplastic anemia treatment
September 2001
Presence of bcr-abl in CML patients increases relapse risk long after BMT
August 2001
Graft-versus-host disease higher after stem-cell transplants
New bone marrow transplant approach offers hope for multiple myeloma treatment
Pneumococcal infections rarely fatal in pediatric transplant recipients
New approach induces transplantation tolerance with minimal myelosuppression
Bone marrow transplantation from unrelated donors gives no disadvantage in childhood ALL
Infection rates similar during neutropenia in allogenic and autologous BMT recipients
July 2001
Lipopolysaccharide antagonism inhibits GVHD but spares antileukemic effects
Treatment outcome of AMKL is often poor in absence of Down syndrome
Hepatocyte growth factor may help control acute GVHD after allogeneic BMT
Polymorphism associated with risk of higher methotrexate toxicity
Immune reconstitution better after blood stem cell allografting than marrow grafting
June 2001
Glucocorticoid use increases fungal infection risk after bone marrow transplant
May 2001
Early infectious complications do occur with nonmyeloablative allogeneic BMT
Lack of sibling donor no impediment to safe bone marrow transplant for CML
April 2001
Some HPV types may be part of commensal microflora of genital mucosa
February 2001
High-dose therapy and ABMT improve outcomes in follicular lymphoma patients
Gene therapy for GVHD supported in preclinical research
Few infectious complications after bone marrow transplantation for breast cancer
Donor T cell reactivity against host keratinocytes predicts GVHD
Risk of solid cancer increased after bone marrow transplantation
January 2001
Peripheral-blood cell transplant has advantages over BMT after chemotherapy for leukemia
November 2000
Bone marrow transplant not helpful in pediatric acute lymphoblastic leukemia
High-dose chemotherapy effective in relapsed testicular cancer
Relapsed CML patients develop potent humoral response to donor-lymphocyte infusion
Short inventory simplifies symptom assessment in cancer patients
September 2000
Leukemic progenitor cell assay predicts response to chemotherapy
Pediatric bone marrow recipients have high long-term risk for diabetes
Superantigen T-cell response enhances antitumor activity
July 2000
G-CSF appears beneficial with stem cell transplantation in children
May 2000
Vaccine prolongs relapse-free survival following murine bone marrow transplant
April 2000
Intensive therapy advised for children with Ph-positive acute lymphoblastic leukemia
February 2000
Aetna unit to drop bone marrow transplant coverage for breast cancer patients
Researcher admits misrepresenting results of breast cancer trial
December 1999
Ifosfamide/carboplatin/etoposide superior to other regimens for non-Hodgkin's lymphoma
Stem cell transplant better than bone marrow transplant for some leukemias
October 1999
New treatment protocols improve outcomes of children with high-risk neuroblastoma
August 1999
IL-11 treatment reduces severity of GVHD after bone marrow transplant in mice
July 1999
Depletion of host antigen-presenting cells may prevent GVHD
Some pediatric cancer patients with fever and neutropenia can be treated as outpatients
June 1999
Novel cytoreductive regimen effective in patients with refractory Hodgkin's disease
May 1999
HLA-mismatched bone marrow transplants successful after non-myeloablative therapy
Jury still out on efficacy of high-dose chemo and BMT in breast cancer
April 1999
Role of high-dose chemo plus BMT in breast cancer treatment still inconclusive
February 1999
Identification of stem-cell migration receptor may lead to improved bone marrow transplantation
January 1999