Dear OncoLink "Ask The Experts,"
Following debulking surgery for advanced ovarian cancer, how soon should chemotherapy be commenced? Does early commencement compromise wound healing?
Christina S. Chu, MD, Assistant Professor of the Division of Gynecologic Oncology at the University of Pennsylvania Health System, responds:
Following extensive debulking surgery, chemotherapy may start as soon as 7-10 days after surgery, if the patient's clinical status allows. Small studies of the effect of post-operative chemotherapy on wound healing show that there is no increased risk of wound infection following chemotherapy. Other factors such as surgical technique, body habitus, medical co-morbidities, etc may actually be more influential in wound healing than early commencement of chemotherapy.
Jul 12, 2012 - After adjusting for prognostic variables, patients who receive adjuvant chemotherapy following resection of periampullary adenocarcinomas have improved survival compared with those who receive only observation, according to a study published in the July 11 issue of the Journal of the American Medical Association.
Mar 26, 2010
Jul 11, 2011