- Cancer Types
Information about risk, prevention, screening, symptoms, diagnosis, treatment, and support for all cancers Cancer A to Z - Cancer Treatment
Cancer Treatment
Information about cancer treatment, including surgery, chemotherapy, radiation therapy, clinical trials, proton therapy, complementary medicine, and cutting edge technologies.
- Risk and Prevention
- Cancer Drugs
- Support
Support
Ways for cancer patients and caregivers to cope with cancer, side effects, nutrition, general cancer support issues, grief/end of life issues, and shared survivor's experiences.
- Healthcare Professionals
- Clinical Trials
My Patient Treatment Binder
OncoLink Blogs
What's My Cancer Risk?
OncoPilot: Navigating Your Cancer Journey
Community Events Calendar
OncoLink eNews
Abramson Cancer CenterNCI CANCERLIT® Search: Salivary Gland Cancer - June 2002
National Cancer Institute®
Last Modified: June 1, 2002
- Immunohistochemical expression of CA19-9 and CA125 in mucoepidermoid and adenoid cystic carcinomas of the salivary gland.
- [Myoepithelioma of the parotid gland]
- Parotidectomy in the treatment of aggressive cutaneous malignancies.
- Synchronous ipsilateral cerebellopontine angle glossopharyngeal schwannoma and parotid adenoid cystic carcinoma.
- Multiple primary pleomorphic adenomas in a single parotid gland: report of a new case.
- Malignant eccrine acrospiroma with metastasis to the parotid.
- Salivary gland neoplasia: a review for the practicing pathologist.
- Acinic cell carcinoma of the sublingual gland accompanied by bone formation.
- Expression of estrogen receptor, progesterone receptor, and insulin-like growth factor receptor-1 and of MIB-1 in patients with recurrent
- Upper lip swelling. Benign salivary gland tumor.
- Role of fine needle aspiration cytology in diagnosis of pleomorphic adenomas.
- Molecular analysis of chromosome 16q regions in dermal analogue tumors of salivary glands: a genetic link to dermal cylindroma?
- Submandibular synovial sarcoma with t(X;18) and synovial sarcoma of the toe with additional cytogenetic abnormalities: presentation of two cases
- Pleomorphic adenoma of the lower lip: report of a case.
- [Giant hemangioendothelioma of the parotid gland in an infant]
- Granular cell tumor of the parotid gland. A case report.
- Clinicopathological evaluation of parotid gland tumors: a retrospective study.
- Expression of PLAG1 and HMGIC proteins and fusion transcripts in radiation-associated pleomorphic adenomas.
- [Cell proliferation in salivary gland tumors]
Table of Contents
1
UI - 11978546
AU - Okamura K; Kiyoshima T; Shima K; Kobayashi I; Matsuo K; Ishibashi H;
TI -
Komatsu S; Rasul AM; Sakai H
Immunohistochemical expression of CA19-9 and CA125 in mucoepidermoid and
adenoid cystic carcinomas of the salivary gland.
SO - Oral Oncol 2002 Apr;38(3):244-50
AD - Department of Oral Pathology, Fukuoka Dental College, 2-15-1 Tamura,
Sawara-ku, 814-0193, Fukuoka, Japan.
This study examined the immunohistochemical expression of carbohydrate
antigens CA19-9 and CA125 and their relationship to various biological
parameters in 27 mucoepidermoid carcinomas (MEC) and 18 adenoid cystic
carcinomas (ACC) arising from salivary glands. The series showed higher
immunopositivity for CA125 (67% for MEC; 33% for ACC) than for CA19-9
(59% for MEC; 11% for ACC). CA19-9 epitope was mainly expressed in
cystic (MEC) and cribriform/tubular (ACC) components of carcinoma
tissues. Solid components in MEC occasionally showed positive staining
for CA19-9. CA125 was evenly expressed in both ACC and MEC tissues
regardless of their different histological components. The positive
expression of CA19-9 and CA125 in the carcinoma tissues did not
influence the clinical course of patients with MEC and ACC. A
significant relationship was only demonstrated between the
immunohistochemical expression of CA125 and the low proliferative
activity (LI) evaluated by Ki-67 immunohistochemistry. However, no
significant relationship was found between LI and the patients' clinical
course. These results suggest that the immunostaining for CA19-9 and
CA125 provide no reliable data to predict the clinical course of
patients with MEC and ACC of the salivary glands.
2
UI - 11962002
AU - Almela Cortes R; Garcia-Hirschfeld Garcia JM; Ramos Lopez B
TI -
[Myoepithelioma of the parotid gland]
SO - An Otorrinolaringol Ibero Am 2002;29(1):53-9
AD - Servicio ORL, Hospital General de Especialidades Ciudad de Jaen, Jaen.
Myoepithelioma of the salivary gland is a benign tumor set up almost
exclusively for myoepithelial cells. It is considered as the terminal
form of the histopathologic spectrum of mixed tumors, but owing to its
monomorphic appearance is considered an aside form. In this article is
reported one myoepithelial case of the parotid gland and are also
reviewed the published literature of this sort of neoplasms.
3
UI - 12003582
AU - Lai SY; Weinstein GS; Chalian AA; Rosenthal DI; Weber RS
TI -
Parotidectomy in the treatment of aggressive cutaneous malignancies.
SO - Arch Otolaryngol Head Neck Surg 2002 May;128(5):521-6
AD - Department of Otorhinolaryngology-Head and Neck Surgery, University of
Pennsylvania Medical Center, 5 Silverstein/Ravdin, 3400 Spruce St,
Philadelphia, PA 19104, USA.
BACKGROUND: Aggressive nonmelanoma skin cancer (ANMSC) of the head and
neck may require parotidectomy because of neurotropic spread, direct
invasion of the parotid gland, or parotid metastasis. OBJECTIVE: To
review our experience with parotidectomy in the treatment of these
tumors to examine the indications for this procedure and to analyze
treatment outcomes. We emphasize the importance of early identification
of an ANMSC and a systematic approach to treatment. DESIGN: Review of 23
patients with an ANMSC who required parotidectomy with or without facial
(VII) nerve sacrifice between January 5, 1996, and December 27, 1999.
Median follow-up for all patients was 24 months. SETTING: Academic
tertiary care referral center. PATIENTS: This study focused on 23
(median age, 71 years) of 54 patients treated for an ANMSC. Most tumors
were in the periauricular (n = 9) and the frontozygomatic (n = 6) areas.
Seven patients presented with facial weakness or paralysis. Three
patients had clinically evident parotid metastasis, while 14 patients
had tumors directly invading the parotid gland. Eighteen patients had
recurrent disease that had been treated previously with Mohs
micrographic surgery. INTERVENTIONS: Following wide local excision of
the ANMSC, 12 patients had resection of the lateral parotid lobe with
preservation of the nerve, while 11 required radical parotidectomy with
sacrifice of 1 or more branches. Nineteen patients received cervical
lymphadenectomy. Postoperative radiotherapy was administered in 19
patients. MAIN OUTCOME MEASURES: Tumor pathologic findings
(specifically, perineural invasion of the facial nerve), locoregional
control or recurrence, disease-free survival, disease-specific survival,
and overall survival. RESULTS: Neurotropic spread to the facial nerve
was present in 6 patients and was more likely to occur in younger
patients (51 vs 75 years, P =.006). Locoregional failures occurred in 9
patients following treatment. Patients who required parotidectomy in
their surgical treatment for an ANMSC were more likely to have recurrent
disease (P =.0002). Disease-specific and overall survival was 79% and
69%, respectively, at 42 months. CONCLUSIONS: Patients with ANMSC may
require parotidectomy in the context of neurotropic spread, regional
metastasis, or direct invasion into the parotid gland. Surgery combined
with postoperative radiotherapy is necessary in most patients because of
adverse clinical and pathologic findings. A systematic approach to the
management of the parotid and facial nerve in the presence of these
aggressive tumors is required. Despite comprehensive treatment, local
recurrence of ANMSC and mortality remain high.
4
UI - 11997785
AU - Lin SJ; Dutra JC; Ostrowski VB
TI -
Synchronous ipsilateral cerebellopontine angle glossopharyngeal
schwannoma and parotid adenoid cystic carcinoma.
SO - Otolaryngol Head Neck Surg 2002 Apr;126(4):423-5
AD - Department of Otolaryngology-Head and Neck Surgery, Northwestern
University Medical School, Chicago, IL 60611, USA. samjlin@hotmail.com
5
UI - 12025006
AU - Tanimoto H; Kumoi K; Otsuki N; Hirayama Y
TI -
Multiple primary pleomorphic adenomas in a single parotid gland: report
of a new case.
SO - Ear Nose Throat J 2002 May;81(5):341-5
AD - Department of Otolaryngology, Himeji National Hospital, Hyogo, Japan.
hitoshi@tc4.so-net.ne.jp
The development of multiple primary pleomorphic adenomas in a single
parotid gland is extremely rare in previously untreated patients, as
only nine cases have been previously reported. In this article, we
report the tenth such case, which occurred in an 87-year-old Japanese
women. We also report the results of our 7-plus-year review of the types
of parotid tumors seen at our institution. We identified 98 tumors in 89
patients; pleomorphic adenomas were the most common tumors, accounting
for 45.9% of the total.
6
UI - 12025008
AU - Holden B; Colome-Grimmer M; Savage C; Stierman K; Pou AM
TI -
Malignant eccrine acrospiroma with metastasis to the parotid.
SO - Ear Nose Throat J 2002 May;81(5):352-5
AD - Department of Surgery, Baylor University Medical Center, Dallas, USA.
Malignant eccrine acrospiromas are rare. Clinically, they resemble other
cutaneous lesions. A high index of suspicion must be maintained in cases
of histologically benign eccrine acrospiromas for three reasons: (1)
malignant transformation can occur, (2) the presence of both benign and
malignant tissue can lead to a false-negative diagnosis if only the
benign component is obtained in the biopsy specimen, and (3)
benign-appearing tumors can recur locally or metastasize. The primary
treatment is wide local excision with or without lymph node dissection.
The efficacy of adjuvant chemotherapy and radiation therapy requires
further investigation. We describe a case of malignant eccrine
acrospiroma in an 80-year-old man, and we review the literature on this
tumor, with emphasis on the differential diagnosis.
7
UI - 11904344
AU - Zarbo RJ
TI -
Salivary gland neoplasia: a review for the practicing pathologist.
SO - Mod Pathol 2002 Mar;15(3):298-323
AD - Department of Pathology, Henry Ford Hospital, Detroit, Michigan 48202,
USA. rzarbo1@hfhs.org
8
UI - 12030442
AU - Ota Y; Arai I; Aoki T; Yamazaki H; Karakida K; Tsukinoki K
TI -
Acinic cell carcinoma of the sublingual gland accompanied by bone
formation.
SO - Tokai J Exp Clin Med 2001 Dec;26(4-6):127-30
AD - Department of Oral Surgery, Tokai University School of Medicine,
Isehara, Kanagawa, Japan. yota@is.icc.u-tokai.ac.jp
A rare case of acinic cell carcinoma of the sublingual gland accompanied
by bone formation is reported. The patient is a 79-year-old male who was
referred to Yokohama Minami Kyosai Hospital with sublingual swelling. A
tumor mass, 20 x 10 mm in diameter, was detected on the right side of
the floor of the mouth. Computed tomography (CT) revealed a mass lesion
with calcification in the sublingual gland. The patient underwent total
sialadenectomy of the sublingual gland with conservation of the lingual
nerve. Histologically, the lesion showed amylase-positive atypical cells
with thyroid gland-like arrangement, and mature bone tissue in the
stroma. Based on these findings, the tumor was diagnosed as acinic cell
carcinoma accompanied by bone formation. Postoperative recovery was
uneventful, and two years after surgery, there are no signs of distant
metastases or recurrence.
9
UI - 12001119
AU - Glas AS; Hollema H; Nap RE; Plukker JT
TI -
Expression of estrogen receptor, progesterone receptor, and insulin-like
growth factor receptor-1 and of MIB-1 in patients with recurrent
pleomorphic adenoma of the parotid gland.
SO - Cancer 2002 Apr 15;94(8):2211-6
AD - Department of Surgical Oncology, University Hospital Groningen,
Groningen, The Netherlands.
BACKGROUND: Patients with recurrent pleomorphic adenomas of the parotid
gland are difficult to manage without considerable risk of facial nerve
injury. The prognostic significance of progesterone receptor (PR) and
estrogen receptor (ER) reported in these adenomas was evaluated in
patients with recurrent pleomorphic adenomas, comparing the results in a
group of patients with primary adenomas without recurrences during 10
years of follow-up. METHODS: Paraffin embedded tumor samples from 52
patients with recurrent pleomorphic adenoma of the parotid gland were
collected and stained immunohistochemically. Expression of PR, ER, Ki-67
antigen, and insulin-like growth factor receptor-1 (IGFR-1) was analyzed
in resected samples of recurrent tumors and was compared with samples
from a control group of patients with primary pleomorphic adenoma.
RESULTS: A difference (P < 0.05) in the type of tumor was observed
between the recurrent group (more cell-poor variants) and the control
group. ER expression was low in both groups (19% and 17%, respectively),
but immunoreactivity for ER was higher (48%) in normal parotid gland
tissue. PR expression in the recurrent group (96%) was higher compared
with PR expression in the control group (61%; P < 0.001). PR expression
and IGFR-1 expression were correlated weakly (correlation coefficient =
0.660; P = 0.053) in the recurrent group. The expression of growth
fraction (Ki-67 score) and IGFR-1 was similar in both groups but was
more extensive compared with normal parotid gland tissue. CONCLUSIONS:
PR seems to be a prognostic factor in recurrent pleomorphic adenoma of
the parotid gland. The PR pathway can be considered a potential target
for hormone treatment in patients with these recurrent adenomas.
Copyright 2002 American Cancer Society.
10
UI - 12004723
AU - Fantasia JE; Damm DD
TI -
Upper lip swelling. Benign salivary gland tumor.
SO - Gen Dent 2001 May-Jun;49(3):265, 324
AD - Division of Oral Pathology, Department of Dental Medicine, Long Island
Jewish Medical Center, New Hyde Park, NY, USA.
11
UI - 11952751
AU - Verma K; Kapila K
TI -
Role of fine needle aspiration cytology in diagnosis of pleomorphic
adenomas.
SO - Cytopathology 2002 Apr;13(2):121-7
AD - Cytology Laboratory, Department of Pathology, All India Institute of
Medical Sciences, Ansari Nagar, New Delhi 110029, India.
This retrospective study was carried out to review the cases diagnosed
as pleomorphic adenoma in major or minor salivary glands and determine
the difficulties encountered on typing this tumour on fine needle
aspiration cytology (FNAC). Over a 19-year period (1982-2000) 488
pleomorphic adenomas were diagnosed on FNAC from different sites
(parotid - 372 cases, submandibular - 95 cases; oral cavity - 21 cases).
Histology was available in 232 cases. Twenty-nine cases where a
histological diagnosis of pleomorphic adenoma was made but the
cytological diagnosis was variable were also reviewed. In 216 of the 232
cases a good cytohistological correlation was available. On review only
4 of the 16 cases initially diagnosed as pleomorphic adenoma on FNAC
where the histology revealed a different tumour were categorized as
pleomorphic adenoma, while 3 each were classified as adenoid cystic
carcinoma and benign tumour ?type, and 2 each were diagnosed to be
muco-epidermoid carcinoma, monomorphic adenoma and acinic cell
carcinoma. On review of the FNAC smears from 29 cases where a
histological diagnosis of pleomorphic adenoma was available while the
cytological diagnosis was variable, only 11 (38%) were categorized as
pleomorphic adenoma. In the majority of the remaining cases the
cytological diagnosis did not alter markedly, 7 of 10 cases where the
tumour could not be typed on cytology initially could not be typed even
on review. In conclusion, FNAC is an ideal, fairly accurate preoperative
procedure for the diagnosis of pleomorphic adenomas. Certain diagnostic
problems occur in differentiating pleomorphic adenomas from adenoid
cystic carcinoma, monomorphic adenoma and mucoepidermoid carcinoma.
Carcinoma ex-pleomorphic adenoma is difficult to identify on FNAC and in
our series all 4 such cases on histology were considered benign on
cytology.
12
UI - 12023583
AU - Choi HR; Batsakis JG; Callender DL; Prieto VG; Luna MA; El-Naggar AK
TI -
Molecular analysis of chromosome 16q regions in dermal analogue tumors
of salivary glands: a genetic link to dermal cylindroma?
SO - Am J Surg Pathol 2002 Jun;26(6):778-83
AD - Department of Pathology, University of Texas M.D. Anderson Cancer
Center, Houston 77030, USA.
Dermal analogue tumor, an uncommon subtype of basal cell monomorphic
adenoma of the parotid gland, has a remarkable clinical and histologic
resemblance to dermal cylindroma. Molecular studies of familial and
sporadic cylindromas have shown frequent alterations at chromosome
16q12-13 that have recently been found to house the cylindromatosis gene
(CYLD). To determine the involvement of the chromosome 16q12-13 region
in dermal analogue tumors, we performed loss of heterozygosity analysis
using microsatellite markers flanking the cylindromatosis gene locus in
21 sporadic dermal analogue salivary tumors and 12 salivary and dermal
lesions from two sisters. Loss of heterozygosity was identified in 17
(80.9%) of the 21 sporadic tumors and in nine of the 12 dermal and
salivary gland dermal analogue tumors from the two sisters; a
parathyroid adenoma from one sister and two lymphoepithelial lesions
from the second sister showed no microsatellite alterations.
Microsatellite instability was only identified in three sporadic tumors
at marker D16S308. Markers D16S409 (centromeric), D16S541, and D16S308
(telomeric) to the CYLD gene showed the highest incidence of loss of
heterozygosity (>65%). The minimally deleted region was flanked
proximally by marker D16S389 and distally by marker D16S419 and spanned
the 771.5-megabase fragment that included the CYLD locus. We conclude
that dermal analogue tumor and cylindroma share similar incidence of
alterations at the 16q12-13 region, supporting a common molecular
origin.
13
UI - 12034530
AU - Udayakumar AM; Sundareshan TS; Mukherjee G; Biswas S; Rajan KR;
TI -
Prabhakaran PS
Submandibular synovial sarcoma with t(X;18) and synovial sarcoma of the
toe with additional cytogenetic abnormalities: presentation of two cases
and review of the literature.
SO - Cancer Genet Cytogenet 2002 Apr 15;134(2):151-5
AD - Cytogenetics Unit, Department of Pathology, Kidwai Memorial Institute of
Oncology, 560 029, Bangalore, India. tssundri@vsnl.com
We report cytogenetic findings from fine-needle aspiration samples of
two synovial sarcoma patients. The cases are of interest because (1) one
case is of a rare site (submandibular region) of the head and neck, and
(2) the other is a patient with synovial sarcoma of the toe showing
additional cytogenetic abnormalities along with t(X;18). The literature
of this tumor is reviewed.
14
UI - 12022109
AU - To EW; Tsang WM; Tse GM
TI -
Pleomorphic adenoma of the lower lip: report of a case.
SO - J Oral Maxillofac Surg 2002 Jun;60(6):684-6
AD - Division of Head and Neck, Plastic and Reconstructive Surgery,
Department of Surgery, The Chinese University of Hong Kong, Hong Kong.
edwardtowh@yahoo.com
15
UI - 11998433
AU - Rakotoarisoa B; Rantomalala Y; Raharisolo C; Rajaonarivony T;
TI -
Rajaonarison M; Andrianandrasana A
[Giant hemangioendothelioma of the parotid gland in an infant]
SO - Arch Pediatr 2002 Apr;9(4):442
16
UI - 12040652
AU - Chae SW; Sohn JH; Shin HS
TI -
Granular cell tumor of the parotid gland. A case report.
SO - Acta Cytol 2002 May-Jun;46(3):550-4
AD - Department of Pathology, Hangang Sacred Heart Hospital, College of
Medicine, Hallym University, 94-200, Yeongdungpo-Dong, Yeongdeungpo-Ku,
Seoul 150-020, Korea.
BACKGROUND: Granular cell tumor (GCT) is a relatively uncommon soft
tissue tumor of putative Schwann cell origin. This tumor can occur in
multiple sites as a small, nontender nodule, but the parotid gland is
unusual, and only several cases have been reported. CASE: A 46-year-old
woman presented with a slowly growing mass in the left preauricular
region for three years. Imaging studies confirmed a nodular lesion in
the superficial lobe of the left parotid gland. Fine needle aspiration
(FNA) cytology revealed scattered cellular clusters and single cells
with abundant granular cytoplasm and indistinct cell borders. Background
exhibited eosinophilic, granular, cytoplasmic material, and some
scattered naked nuclei were also noted. Histologic examination with
supportive immunohistochemical and ultrastructural studies confirmed
GCT. CONCLUSION: GCT of the parotid gland is very unusual. Recognition
of this tumor is important to make a definitive diagnosis before an
operation. FNA is useful procedure in GCT of parotid gland for a
preoperative diagnosis and proper treatment.
17
UI - 11886987
AU - Sungur N; Akan IM; Ulusoy MG; Ozdemir R; Kilinc H; Ortak T
TI -
Clinicopathological evaluation of parotid gland tumors: a retrospective
study.
SO - J Craniofac Surg 2002 Jan;13(1):26-30
AD - Department of Plastic & Reconstructive Surgery, Ankara Numune Hospital,
Ankara, Turkey.
1995 were reviewed for their clinical presentation, diagnostic
evaluation, pathological diagnosis, treatment modalities, and age and
sex distribution. An asymptomatic mass was the most common clinical
presentation. All of the operations were performed by the same surgical
team. Total and superficial parotidectomy was used for the treatment of
the lesions and none of the patients underwent limited excision.
Retrograde approach in 79 (34.4%) patients and anterograde approach in
151 (65.6%) was used. Eighteen patients with malignant tumors were
followed up in cooperation with the radiation oncology clinic. Tumors
were classified according to their histopathologic diagnosis. Among 192
(83%) benign and 38 (17%) malignant tumors, the most common benign tumor
of parotid gland was pleomorphic adenoma (79.1%) while the most common
malignant lesion was adenocystic carcinoma (44.7%). Incidences of
pleomorphic adenoma, adenocystic and epidermoid carcinoma were greater
in male patients. Complication rates in benign and malignant tumors were
presented and statistically significant difference could not be found
between anterograde and retrograde approach in terms of facial nerve
injury (P > 0.05).
18
UI - 11894114
AU - Enlund F; Nordkvist A; Sahlin P; Mark J; Stenman G
TI -
Expression of PLAG1 and HMGIC proteins and fusion transcripts in
radiation-associated pleomorphic adenomas.
SO - Int J Oncol 2002 Apr;20(4):713-6
AD - The Lundberg Laboratory for Cancer Research, Department of Pathology,
Goteborg University, Goteborg, Sweden.
Extensive cytogenetic investigations of pleomorphic adenomas of the
salivary glands have unequivocally demonstrated that they are
cytogenetically monoclonal and are characterized by a high frequency of
tumor specific chromosome abnormalities involving in particular
chromosome bands 3p21, 8q12 and 12q14-15. Here we show that two
radiation-associated and cytogenetically polyclonal adenomas without
gross rearrangements of these breakpoints show simultaneous
overexpression of the PLAG1 and HMGIC genes, i.e. the target genes of
the 8q12 and 12q14-15 rearrangements in sporadic adenomas. In addition,
one of the tumors expressed a cryptic CTNNB1-PLAG1 fusion transcript.
Our findings strongly suggest that identical or very similar molecular
mechanisms are operating during adenoma tumorigenesis irrespective of
whether the tumors are cytogenetically polyclonal or whether they have
non-random, tumor specific abnormalities. Cytogenetically polyclonal
adenomas are thus most likely also of monoclonal origin.
19
UI - 11692959
AU - Frade Gonzalez C; Garcia-Caballero T; Lozano Ramirez A; Labella
TI -
Caballero T
[Cell proliferation in salivary gland tumors]
SO - Acta Otorrinolaringol Esp 2001 Aug-Sep;52(6):456-60
AD - Servicio de O.R.L., Hospital Clinico de Santiago, Santiago de
Compostela, La Coruna.
Previous studies on cell proliferation in salivary gland tumors have
shown the utility of immunostain with MIB1 in the differential diagnosis
and prognosis of these neoplasms. We have carried out a study of 39
salivary gland tumors (17 benign), from different histological lineages.
The immunocytochemical method used was the
streptavidin--biotin--peroxidase complex which used the MIB1 monoclonal
antibody. Benign tumors showed a low cell proliferation rates, below 5%
with an overall average of 1.9%. The malignant tumors presented higher
rates, with a middle value of 17.85%. Epidermoid carcinomas had the
higher cell proliferation rates, with an average of 43%. In adenoid
cystic carcinomas, we have observed that proliferation was greater at
the peripheral level of tumor nests and cell surrounding the cystic
structures. Neoplasms of low grade of malignancy presented lower cell
proliferation rates. The MIB1 immunostain allowed to reach a
differential diagnosis between pleomorphic adenoma and adenoid cystic
carcinoma, specially in those cases in which there could be any doubt.
The above citations and abstracts reflect those newly added to CANCERLIT for the month and topic listed in the title. The citations have been retrieved from CANCERLIT using a predefined search strategy of indexed subject terms. Although the search strategy has been refined as best as possible, citations may appear that are not directly related to the topic, and occasionally relevant references may be omitted.
Cancer Types
Bone Cancer
Brain Tumors
Breast Cancer
Carcinoid Tumors
Endocrine System Cancers
Gastrointestinal Cancers
Gynecologic Cancers
Head and Neck Cancers
Leukemia
Lung Cancers
Lymphomas
Myelomas
Pediatric Cancers
Penile Cancer
Prostate Cancer
Sarcomas
Skin Cancers
Testicular Cancer
Thyroid Cancer
Urinary Tract Cancers
OncoLink Vet
Cancer Treatment
Biologic Therapy
Bone Marrow Transplants
Chemotherapy
Clinical Trials
Complementary Medicine
Gene Therapy
General Treatment Concerns
Hormone Therapy
PDT Center
Proton Therapy
Radiation Oncology
Surgical Oncology
Targeted Therapies
Vaccine Therapies
Cancer Support
Caregivers
Hospice Care and Bereavement
Nutrition and Cancer
Sexuality & Fertility
Side Effects
Support
Survivorship
Exercise and Cancer
Cancer Resources
Cancer News
OncoLink University
Nurses' Notes
Conferences
Newly Diagnosed Patients
Causes and Prevention
Legal and Financial Information for Patients
LGBT Resources
NCI Resources
Global Resources
Cancer Resource List
Resources for Young Adults
OncoLink Media Library
OncoLink TV
Book, Music and Video Reviews
Ask the Experts
Brown Bag Chat
Tracy's Corner
About OncoLink
About OncoLink
Giving to OncoLink
Contact Information
Usage Policy
Editorial Board
How to Partner with OncoLink
Link to OncoLink
Mission Statement
