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Abramson Cancer CenterNCI CANCERLIT® Search: Small Intestine Cancer - August 2002
National Cancer Institute®
Last Modified: August 1, 2002
- Small bowel intussusception caused by lymphomatous polyposis in a patient with AIDS.
- Spontaneous pyeloduodenal fistula: an unusual presentation in advanced renal transitional cell carcinoma.
- Metastatic tumors to the upper gastrointestinal tract: endoscopic experience.
- Gastric-type adenocarcinoma of the duodenal second portion histogenetically associated with hyperplasia and gastric-foveolar
- Carcinoid syndrome from gastrointestinal carcinoid tumor without distant metastases.
- [A case of AFP producing endocrine cell carcinoma of the duodenum]
- [A case of gastrointestinal stromal tumor of the duodenum with increased color flow signals]
- Multivisceral resection for colon cancer.
- [A case of ileus-peritonitis like a complication from small intestine metastatic malignant melanoma]
- Duodenal carcinoid tumors: how aggressive should we be?
- Low-grade follicular lymphoma of the small intestine.
- [Surgical treatment of endocrine-cell tumors of hepato-pancreatic-duodenal zone (comment of the editor)]
- Laparoscopically assisted panenteroscopy.
- The use of ultrasound to demonstrate small bowel polyps in a patient with Peutz-Jeghers syndrome.
- Pain management of patients with unresectable peripancreatic carcinoma.
- Case record of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 26-2002. An 87-year-old woman with
Table of Contents
1
UI - 9128353
AU - Finkle HI
TI -
Small bowel intussusception caused by lymphomatous polyposis in a
patient with AIDS.
SO - Am J Gastroenterol 1997 Apr;92(4):726-7
2
UI - 12137849
AU - Chen CH; Cheng HL; Tong YC; Pan CC
TI -
Spontaneous pyeloduodenal fistula: an unusual presentation in advanced
renal transitional cell carcinoma.
SO - Urology 2002 Aug;60(2):345
AD - Department of Urology, National Cheng Kung University Hospital and
Medical College, Tainan, Taiwan.
Spontaneous pyeloduodenal fistula is extremely rare. Most of the
etiologies belong to chronic renal inflammatory disease, especially in
patients with renal calculi. In published studies, only 2 cases have
been reported in association with renal malignancy. We report a case of
spontaneous pyeloduodenal fistula associated with transitional cell
carcinoma, which has not been previously described in published reports.
3
UI - 1415098
AU - Kadakia SC; Parker A; Canales L
TI -
Metastatic tumors to the upper gastrointestinal tract: endoscopic
experience.
SO - Am J Gastroenterol 1992 Oct;87(10):1418-23
AD - Department of Medicine, Brooke Army Medical Center, San Antonio
78234-6200.
Metastatic tumors to the upper gastrointestinal tract were identified by
esophagogastroduodenoscopy in 14 patients. Malignant melanoma, breast
cancer, and lung cancer were the most common primary cancers in four,
three, and three patients, respectively. Osteogenic sarcoma, renal cell
carcinoma, Meckel cell carcinoma of the skin, and germ-cell tumor were
the primary cancer in the remaining four. The esophagus was involved in
three patients, the stomach in 13, duodenum in four, and papilla of
Vater in one. Upper gastrointestinal bleeding and anemia were the most
common presenting features. There was correlation between symptoms and
endoscopic findings in all patients. Involvement of gastrointestinal
tract at endoscopy was the initial and only evidence of metastases in
all patients without evidence of metastases elsewhere, as evidenced by
other diagnostic tests in any of these patients. Endoscopic biopsies
and/or brush cytology provided histologic diagnosis in all 14 patients.
The endoscopic and nonendoscopic literature regarding metastases to the
upper gastrointestinal tract is reviewed.
4
UI - 12070607
AU - Kushima R; Stolte M; Dirks K; Vieth M; Okabe H; Borchard F; Hattori T
TI -
Gastric-type adenocarcinoma of the duodenal second portion
histogenetically associated with hyperplasia and gastric-foveolar
metaplasia of Brunner's glands.
SO - Virchows Arch 2002 Jun;440(6):655-9
AD - Department of Clinical Laboratory Medicine, Shiga University of Medical
Science, Seta, Otsu, Shiga 520-2192 Japan. kushima@belle.shiga-med.ac.jp
We report a case of a pedunculated polyp with a focus of gastric-type
adenocarcinoma arising in the opposite side of the papilla Vater of the
duodenal second portion. The carcinoma was surrounded by lobules of
hyperplastic Brunner's glands. Immunohistochemically the carcinoma
tissue showed both gastric foveolar-type mucin ( MUC5AC) and
pyloric/Brunner's gland-type mucin ( MUC6), in which proliferating cells
positive for MIB-1 (Ki-67) were scattered diffusely. Most of the
hyperplastic Brunner's glands were positive for MUC6, while cells toward
the lumen in the superficial layer were positive for MUC5AC and MIB-1.
This directional pattern of differentiation of Brunner's glands has
recently been demonstrated by our group in the histogenetic course of
gastric metaplasia originating directly from Brunner's glands. Therefore
the present carcinoma is thought to have developed under induction of
gastric-foveolar differentiation in a manner very similar to that of
gastric metaplasia in hyperplastic Brunner's glands.
5
UI - 12080244
AU - Cooper MA; Smith A; Khalifa M
TI -
Carcinoid syndrome from gastrointestinal carcinoid tumor without distant
metastases.
SO - J Clin Gastroenterol 2002 Jul;35(1):106-7
6
UI - 12170708
AU - Takashima H; Kimura H; Nakamura H; Myojo S; Okuyama Y; Sugeta N; Yagi N;
TI -
Kutsumi H; Suyama Y; Fujimoto S; Hosokawa Y
[A case of AFP producing endocrine cell carcinoma of the duodenum]
SO - Nippon Shokakibyo Gakkai Zasshi 2002 Jul;99(7):798-802
AD - Kyoto First Red Cross Hospital.
7
UI - 12170712
AU - Maeda N; Mitsuda A; Koda M; Koda M; Hosoda A; Shiota G; Murawaki Y; Suou
TI -
T; Kawasaki H
[A case of gastrointestinal stromal tumor of the duodenum with increased
color flow signals]
SO - Nippon Shokakibyo Gakkai Zasshi 2002 Jul;99(7):820-7
AD - Second Department of Internal Medicine, Tottori University Faculty of
Medicine.
8
UI - 12173378
AU - Luna-Perez P; Rodriguez-Ramirez SE; De la Barrera MG; Zeferino M;
TI -
Labastida S
Multivisceral resection for colon cancer.
SO - J Surg Oncol 2002 Jun;80(2):100-4
AD - Colorectal Service, Surgical Oncology Department, Hospital de Oncologia,
Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social,
Mexico, D.F., Mexico.
BACKGROUND: There is a lack of appropriate information in regard to the
optimal treatment for colon cancer infiltrating neighboring organs.
OBJECTIVES: The objective of this study is to analyze treatment results
and to identify the risk factors of death by cancer in these patients.
METHODS: A retrospective analysis of 40 patients with colon cancer
infiltrating neighboring organs without distant metastases was carried
out. Patterns of recurrence and 5-year survival were analyzed. RESULTS:
The study included 20 males and 20 females with a median age of 51.5
years. Primary tumor location was as follows: right colon (n = 15);
transverse colon (n = 5); left colon (n = 7), and sigmoid (n = 13). In
17 patients, the colon tumor infiltrated the abdominal wall alone or
together with neighboring organs and in 23 patients, one or more
neighboring organs were infiltrated. Eleven patients (27.5%) developed
postoperative complications. Two patients (5%) died during the
postoperative period. Microscopic tumor infiltration was demonstrated in
29 patients (72.5%). Tumor stage was as follows: T3,N0 (n = 8); T3,N+ (n
= 3); T4,N0 (n = 16), and T4,N+ (n = 13). Overall 5-year survival was
45%. Multivariate analysis shows that the unfavorable risk factors for
5-year survival were neoplastic cell infiltration to neighboring organs,
age > 50 years, and lymph node metastases. CONCLUSIONS: The main risk
factors for cancer-related failure are neoplastic infiltration to
neighboring organs, age > 50 years, and lymph node metastases. In T4
colon cancer, the recurrence pattern was found at local, peritoneal, and
distant sites.
9
UI - 12122760
AU - Korukov B; Stoianov S
TI -
[A case of ileus-peritonitis like a complication from small intestine
metastatic malignant melanoma]
SO - Khirurgiia (Sofiia) 2001;57(5-6):45-6
10
UI - 12086896
AU - Zyromski NJ; Kendrick ML; Nagorney DM; Grant CS; Donohue JH; Farnell MB;
TI -
Thompson GB; Farley DR; Sarr MG
Duodenal carcinoid tumors: how aggressive should we be?
SO - J Gastrointest Surg 2001 Nov-Dec;5(6):588-93
AD - Gastroenterology Research Unit and Department of Surgery, Mayo Clinic,
Rochester, Minn. 55905, USA.
Duodenal carcinoid tumors are uncommon. It is not known whether they
behave more like carcinoid tumors in the appendix (indolent course) or
those in the ileum (often virulent)-crucial information for determining
the need for radical resection. A retrospective review at our tertiary
referral center (from 1976 to 1999) identified 27 patients with primary
duodenal carcinoid lesions, excluding functional islet cell tumors.
Endoscopic biopsy provided the diagnosis in 78% of patients. Treatment
was by endoscopic excision (n = 11), transduodenal excision (n = 8),
pancreaticoduodenectomy (n = 3), segmental distal duodenectomy (n = 2),
or palliative operation (n = 2). One patient did not undergo operation
because of comorbidity. Eighteen of 19 patients with tumors smaller than
2 cm remained disease free after local (endoscopic or transduodenal)
excision. The exception was a patient with a small periampullary
carcinoid lesion. In contrast, all four patients with carcinoid tumors 2
cm or larger who were resected for cure developed a recurrence (2 to 9
years postoperatively). We conclude that duodenal carcinoid tumors
smaller than 2 cm may be excised locally; to ensure complete resection
we recommend open transduodenal excision for tumors between 1 and 2 cm.
Endoscopic follow-up is indicated. It is unclear whether patients with
larger tumors benefit from more aggressive locoregional resection.
Ampullary/periampullary carcinoid tumors should be considered
separately, as their behavior is unpredictable.
11
UI - 11782611
AU - Poggi MM; Cong PJ; Coleman CN; Jaffe ES
TI -
Low-grade follicular lymphoma of the small intestine.
SO - J Clin Gastroenterol 2002 Feb;34(2):155-9
AD - Radiation Oncology Sciences Program, National Institutes of Health,
National Cancer Institute, Bethesda, Maryland, USA. mpoggi@usuhs.mil
BACKGROUND: Although the gastrointestinal tract is the most common site
of extranodal non-Hodgkin's lymphoma (NHL), primary small intestine
lymphomas remain relatively rare, especially localized low-grade
follicular B-cell lymphomas. When lymphomas do occur at this site, most
are high grade and require aggressive therapy. We report three cases of
small intestinal follicular lymphoma diagnosed on endoscopic biopsy and
review the clinical history, pathologic features, and treatment outcome.
STUDY: A review of the medical records and pathology from three cases of
small intestine follicular NHL was performed. The pathology specimens
were formalin-fixed, paraffin-embedded tissues processed for routine
microscopic examination, immunohistochemical staining, and molecular
analysis. RESULTS: Histologic and immunophenotypical studies were
diagnostic of grade 1 follicular lymphoma (Revised European-American
Lymphoma classification/World Health Organization classification). All
cases expressed bcl-2 protein, and polymerase chain reaction analysis
supported the diagnosis in two cases with adequate DNA. With 23.3
months' median follow-up, one untreated and one treated patient were
alive without symptoms; a third untreated patient died of a nonlymphoma
cause. CONCLUSION: Isolated indolent lymphomas of the small intestine
are rare. Accurate pathologic staging and histologic classification are
paramount in delineating treatment options.
12
UI - 12001676
AU - Patiutko IuI; Badalian KhV
TI -
[Surgical treatment of endocrine-cell tumors of
hepato-pancreatic-duodenal zone (comment of the editor)]
SO - Khirurgiia (Mosk) 2002;(4):17-21
Endocrine-cell tumors of hepatopancreatoduodenal zone are rare diseases.
Their rate doesn't exceed 1-4% of all tumors of this location. 79
patients with endocrine-cell tumors of hepatopancreatoduodenal zone were
treated, 67 of them underwent surgical treatment (operability was 67.1%)
Radical operations were performed in 45 patients
(gastropancreatoduodenal resection--17, distal resection of the
pancreas--16, tumor enucleation--5, hemihepatectomy--3, liver
resection--4). Prognosis of endocrine-cell tumors of
hepatopancreatoduodenal zone is relatively favorable. In radically
operated patients the presence of metastases to lymph nodes doesn't
influence long-term results which are better than ones of chemo- or
radiotherapy. Correlation between long-term results of surgery and age
of patients, tumor sizes and its histologic structure was not revealed.
Radicality of surgery is the only factor influencing prognosis. It is
necessary to expand indications for extended operations, and to perform
multi-stage operations in some cases of recurrences.
13
UI - 11726871
AU - Sriram PV; Rao GV; Reddy DN
TI -
Laparoscopically assisted panenteroscopy.
SO - Gastrointest Endosc 2001 Dec;54(6):805-6
14
UI - 11972225
AU - Izzidien AY; Davies RA; Masoud AG; Kibru S; Abuhamed A; Lodhi JS; Abid
TI -
G; Jouanroyee A
The use of ultrasound to demonstrate small bowel polyps in a patient
with Peutz-Jeghers syndrome.
SO - Surg Endosc 2002 Apr;16(4):715
AD - Department of Surgery, Prince Charles Hospital, Merthyr Tydfil CF47 9DT,
Wales, UK. ayizzidien@rcsed.ac.uk
A 21-year-old woman presented to the accident and emergency department
with a 2-day history of lower abdominal pain. Her lips had the stigma of
melanosis. Previously, she had received a diagnosis of Peutz-Jeghers
syndrome, although no polyps had been detected in small and large bowel
barium studies performed approximately 8 years before. Clinically, the
patient had mild deep lower abdominal tenderness, and a mass was
palpable in the suprapubic region. Urgent ultrasound showed ileoileal
intussusception and small polyps in the lumen of the small bowel. At
laparotomy, ileoileal intussusception was confirmed. It was not possible
to reduce it because of nonviable small bowel, so 20 cm of the ileum,
including the intussusception, was excised. After this, intraoperative
enteroscopy was performed, showing further polyps in the small bowel
distal and proximal to the intussusception, which were excised locally.
Only a few reports in the literature describe ultrasound used to
diagnose to condition. Intraoperative enteroscopy has been recommended
as the treatment of choice because it allows identification of polyps
that previously would have been missed.
15
UI - 12053225
AU - van Geenen RC; Keyzer-Dekker CM; van Tienhoven G; Obertop H; Gouma DJ
TI -
Pain management of patients with unresectable peripancreatic carcinoma.
SO - World J Surg 2002 Jun;26(6):715-20
AD - Department of Surgery, Academic Medical Center, Meibergdreef 9, PO Box
22660, 1100 DD Amsterdam, The Netherlands.
In patients with unresectable peripancreatic carcinoma, pain is
generally treated with pain medication or with a celiac plexus blockade.
Radiotherapy has also been reported to reduce pain. The efficacy of
these treatment modalities is still under discussion. The aim of this
study was to analyze the effects of the various types of pain management
on patients who underwent palliative bypass surgery for unresectable
1998 a series of 98 patients underwent palliative bypass surgery, mostly
for unresectable disease found during exploration. Patients were divided
into three groups: palliative bypass surgery (BP), palliative bypass
surgery with an intraoperative celiac plexus blockade (CPB), and
palliative bypass surgery with or without celiac plexus blockade
followed by high-dose conformal radiotherapy (RT). Radiotherapy was
performed only in selected patients with locally advanced disease and
without metastases, implying a better prognosis of the last group. The
pain medication consumption, pain medication-free survival,
hospital-free survival, and overall survival were analyzed. The
preoperative consumption of pain medication was significantly higher in
the CPB group than in the BP or RT group. The postoperative consumption
of pain medication in the CPB, BP, and RT groups increased during
follow-up from 15%, 17%, and 13% before surgery to 52%, 57%, and 46%,
respectively, at three-fourths of the survival time (NS). This increase
in consumption of pain medication was not different in the three groups.
In the RT group the median pain medication-free survival was
significantly longer than in the BP or CPB group (9.3 vs. 3.1 and 3.3
months; p = 0.02). The median hospital-free survival and median overall
survival were significantly longer in the RT group than in the CPB group
(10.3 vs. 6.8 months, p = 0.01; and 7.1 vs. 10.8 months, p = 0.01).
Celiac plexus blockade as pain management did not result in an increase
of the pain medication-free survival or overall survival. Therefore a
positive effect of a celiac plexus blockade on pain could not be
confirmed in the present study. Radiotherapy resulted in increased
pain-medication survival, hospital-free survival, and overall survival
compared to celiac plexus blockade. These effects are probably partly
related to patient selection.
16
UI - 12192021
AU - Anonymous
TI -
Case record of the Massachusetts General Hospital. Weekly
clinicopathological exercises. Case 26-2002. An 87-year-old woman with
abdominal pain, vomiting, bloody diarrhea, and an abdominal mass.
SO - N Engl J Med 2002 Aug 22;347(8):601-6
The above citations and abstracts reflect those newly added to CANCERLIT for the month and topic listed in the title. The citations have been retrieved from CANCERLIT using a predefined search strategy of indexed subject terms. Although the search strategy has been refined as best as possible, citations may appear that are not directly related to the topic, and occasionally relevant references may be omitted.
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