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Saturday, November 21, 2009
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Types of Cancer > Prostate Cancer > News

OncoLink Cancer Resources and Reuters News


November 2009

In androgen-deprived prostate CA, zoledronic acid helps BMD even if started late

Short-course hormone therapy improves survival in medium-risk prostate CA


October 2009

In prostate CA, sexual function better with external beam radiotherapy vs cryoablation

Intralesional interferon shows promise for localized prostate cancer

Biochemical failure of high-intensity ultrasound for prostate CA redefined

Pros and cons seen with minimally invasive vs. open radical prostatectomy


September 2009

Treatment often avoided with watchful waiting for prostate cancer

Outcomes improving for conservatively managed prostate cancer

Functional outcome similar after open or laparoscopic prostatectomy

Retrovirus linked to prostate cancer


August 2009

Prostate cancer: racial gap narrows, men diagnosed earlier

Prostate cancer therapy may raise mortality in men with heart disease

Fasting serum insulin level tied to prostate cancer risk

Tallness may up risk of younger onset aggressive prostate cancer

Quality of life better with brachytherapy for endometrial cancer

Denosumab linked to reduced fracture risk during androgen deprivation therapy


July 2009

Robotic surgery for prostate cancer may improve functional outcome

Hormone therapy ups survival of radiation-treated men with prostate cancer

Baseline function predicts long-term QOL after prostate cancer therapy


June 2009

NSAIDs may affect PSA levels and prostate cancer risk

New form of radiotherapy for prostate cancer works in mice

Abirateron benefits patients with castration-resistant prostate cancer

Longer androgen suppression more effective in locally advanced prostate cancer

Risk score predicts several prostate cancer outcomes

Acrylamide exposure not associated with prostate cancer risk


May 2009

Prostate tumor hypoxia may confer resistance to radiotherapy

Young men with advanced prostate cancer have worse prognosis

Inactivated virus induces apoptosis in androgen-resistant prostate cancer cells

Molecular markers in prostate cancer tied to prognosis

Ferumoxtran-10 and MRI help detect metastasis of prostate cancer to lymph nodes

Agent Orange exposure increases risk of aggressive prostate cancer recurrence


April 2009

Statins cut risk of prostate cancer by a factor of three

Androgen deprivation therapy increases fracture risk and cardiovascular death

Hot flashes lessened with steroidal antiandrogen for prostate cancer

Bone health management suboptimal in prostate cancer patients

Longer hormone therapy may improve outcomes in advanced prostate cancer

New antiandrogen agents show promise against advanced prostate cancer


March 2009

Active surveillance safe for men with low-risk prostate cancer

No benefit seen with adjuvant radiotherapy after radical prostatectomy

Stereotactic radiotherapy "promising" for early prostate cancer

Bone-anchored sling relieves urinary incontinence after prostate surgery

PSA screening may yield small reduction in prostate cancer mortality

Selenium and vitamin E have tissue effects in prostate cancer patients

Up to two-thirds of prostate cancers "overdiagnosed"

Diabetes linked to reduced prostate cancer risk

Men in their late 70s with low PSA unlikely to develop aggressive prostate cancer

Prostate cancer anxiety tied to early use of androgen deprivation therapy


February 2009

Ionized serum calcium a potential biomarker of fatal prostate cancer

Surrogate endpoints may predict long-term survival in prostate cancer

Tumor cell count useful for monitoring advanced prostate cancer

Adjuvant radiotherapy useful for pT3N0M0 prostate cancer

Few major complications in 30 days after prostate radiotherapy

Biomarker, potential drug target identified for prostate cancer

Thalidomide may improve progression-free survival in prostate cancer

Engineered measles virus a novel oncolytic prostate cancer therapy


January 2009

Body mass index predicts biochemical recurrence after prostatectomy

Diet modification slows PSA doubling after prostate cancer treatment

Other health issues may be neglected in men with prostate cancer

Dietary fiber intake is not associated with prostate cancer risk

Novel androgen receptor variants tied to hormone-refractory prostate cancer

Her-2/neu expression and DNA index predict prostate cancer outcome

Skin cancer doesn't lower prostate, breast, and colorectal cancer risk

Noscapine may be effective for prostate cancer

With annual prostate cancer screening, new cases are less advanced


December 2008

Younger men with depression at risk for severe post-prostatectomy pain

Androgen deprivation for prostate cancer does not worsen cardiovascular mortality

BK virus may play role in prostate cancer

Chemotherapy does not delay appearance of castrate-resistant prostate cancer

Hormone therapy protects against hematuria after radiotherapy for prostate cancer


November 2008

Artificial sphincter restores urinary continence in prostate cancer patients

Antidiabetic drugs linked to lower prostate cancer risk

Agent Orange exposure linked to doubled risk of prostate cancer

Urine test may reduce unnecessary repeat prostate biopsies


October 2008

Urethral suspension technique improves post-prostatectomy continence

Urethral catheter-less robotic radical prostatectomy decreases patient discomfort

Alendronate enhances skeletal health during androgen-deprivation therapy

Low plasma cholesterol linked to less risk of high-grade prostate cancer

Hyperinsulinemia tied to higher mortality in overweight men with prostate cancer

Body weight, not diabetes, linked with prostate cancer death

Endoscopic prostatectomy effective in obese patients


September 2008

High fall risk seen in prostate cancer patients on androgen deprivation therapy

Pre-brachytherapy hormone therapy linked to greater mortality in older men

Radiation added to hormone therapy beneficial in locally advanced prostate cancer

Novel photodynamic therapy promising for recurrent prostate cancer

Height tied to risk of aggressive prostate cancer

Prostate irradiation raises long-term risk of colon cancer

Short-term mortality increased after prostate biopsy

Gene panel model predicts progression with high-risk prostate cancer


August 2008

Prostate cancer risk increased in obese men

Lower risk seen with radical prostatectomy versus watchful waiting

Recurrence rare after prostatectomy of organ-confined, lower grade cancer

Estrogen patches effective for androgen ablation in prostate cancer

Black-White differences again seen in prostate cancer prognosis

Physical development rate may be tied to prostate cancer risk

Prostate cancer screening not advised for men over 74


July 2008

Second-line doxorubicin/ketoconazole an option in hard-to-treat prostate cancer

Cognitive decline common with hormone therapy for prostate cancer

Active surveillance a good option for some men with early prostate cancer

Immunotherapy may boost prostate cancer response to hormone therapy

Limited benefit seen with docetaxel and rapid androgen cycling for prostate cancer

Anti-osteoclast monoclonal antibody prevents bone loss in prostate cancer

Lymphotropic virus may improve noninvasive detection of metastatic prostate cancer

Preop biomarkers predict prostate cancer relapse

Familial myeloma linked to increased incidence of prostate cancer, MGUS

Androgen blockade for prostate cancer leads to changes in body composition

Circulating tumor cell counts predict course of hard-to-treat prostate cancer


June 2008

Abnormal p53 boosts prostate cancer recurrence

Prostate screening of obese men calls for PSA adjustment

MRI combination best at predicting progression after prostate cancer treatment

HTI-286 shows antitumor activity in prostate cancer

Salvage radiotherapy prolongs prostate cancer survival for some

Lifestyle change alters gene expression in prostate cancer patients

Proscar lowers prostate cancer risk in all men

Prostate cancer therapy unrelated to metabolic syndrome

Vaginal brachytherapy effective for endometrial cancer


May 2008

Vitamin D may be linked to aggressive prostate cancer

Finasteride cuts prostate cancer risk without increase in aggressive disease

Brachytherapy stent benefits patients with advanced esophageal cancer


April 2008

Radical prostatectomy a good option for some older men with prostate cancer

Statin/NSAID combo inhibits androgen-independent prostate cancer growth

REFILE: Reductions in reimbursement linked to changes in prostate cancer treatment

Reductions in reimbursement linked to changes in prostate cancer treatment


March 2008

Investigational GnRH blocker shows potential for advanced prostate cancer

Pretreatment MRI identifies aggressive prostate cancer

Growth protein may provide new target for prostate cancer

Blood test indicates lymph node spread in localized prostate cancer

Potent brachytherapy effective against vaginal cancer


February 2008

Treatment breaks feasible for metastatic prostate cancer

Best treatment for localized prostate cancer remains unclear

Vaccine protects against prostate cancer in mice

Studies detect slew of new genes for prostate risk

Multiplex urine-based diagnostic test for prostate cancer promising

Androgens not associated with risk of ovarian cancer

Chemotherapy can restore endocrine sensitivity in prostate cancer


January 2008

Nerve-sparing prostatectomy improves subsequent continence

DNA fragments may predict prognosis of prostate cancer

Docetaxel every three weeks best for certain metastatic prostate cancers

Effective prostate cancer screening requires digital rectal exam

Comorbidity reduces benefits of androgen suppression in prostate cancer

Androgen-deprivation therapy linked to diabetes

Combination of gene variants strongly linked to prostate cancer

Alprostadil early after prostatectomy facilitates early return of erectile function

Blood transfusion does not increase prostate cancer recurrence risk

Nonfat milk linked to prostate cancer


December 2007

Polymorphism tied to aggressive prostate cancer

Nomogram points to prostate cancer surveillance candidates

Sorafenib active against hormone-refractory prostate cancer

Pelvic node irradiation does not improve survival in localized prostate cancer

Prostate-sparing cystectomy saves erectile function

Nuclear matrix proteins in prostate cancer higher in blacks than whites


November 2007

MR imaging-guided galvanotherapy promising for prostate cancer

Blockade site influences prostate biopsy pain

Obesity, overweight associated with increased prostate cancer mortality

Electromagnetic anisotropy detects prostate cancer noninvasively

Obesity may be protective in progressive prostate cancer

Salvage cryotherapy safe, effective after radiation failure for prostate cancer


October 2007

Brachytherapy effective for young men with prostate cancer

Statins may boost radiation efficacy in prostate cancer

Cardiac disease incidence rises early after starting androgen deprivation therapy

Nestin tied to prostate cancer metastasis

Prostate cancer linked to increased fracture risk

Gefitinib not active against hormone-refractory prostate cancer

Radiotherapy after prostatectomy of little benefit when surgical margins negative

Prostate biopsy site affects cancer detection

Prostate cancer no more aggressive in black men than white men

Topical glyceryl trinitrate eases prostate biopsy discomfort

Algorithm aids prostate cancer salvage therapy


September 2007

Cancer identified in one third of prostate biopsies

'Lumpectomy' may be possible in some cases of prostate cancer

Finasteride does not seem to cause high-grade prostate cancer

Asian men more likely to survive prostate cancer

T-cell coregulatory B7-H3 ligand is a marker of aggressive prostate cancer


August 2007

Prostate cancer screening interval doesn't affect interval tumor rate

External radiation and brachytherapy effective for high-risk prostate cancer

Statins seen to have little impact on androgen levels

Preservation of erectile function excellent after prostate brachytherapy

Obesity predicts prostate cancer recurrence after radiation therapy

Simple patient-education handouts may encourage prostate cancer screening

Zoledronic acid reduces bone damage in prostate cancer patients

Prostate cancer staging assisted by 3D transrectal ultrasonography


July 2007

Prostate cancer prediction not skewed by finasteride

Real-time elastography accurately detects prostate cancer

Venous thromboembolism associated with cyproterone use for prostate cancer

Chromosome 17 variants influence prostate cancer, type 2 diabetes risk


June 2007

Hormonal prostate cancer therapy may boost MI risk

Soy isoflavones may boost efficacy of radiotherapy for prostate cancer

BRCA2 mutation linked to aggressive prostate cancer

High calcium intake linked to increased prostate cancer risk


May 2007

Clodronate no apparent help in curbing prostate cancer

PSA drop not tied to negative repeat prostate biopsy

Hormone response can guide prostate cancer therapy

Patient-reported illness burden gives accurate prognosis in prostate cancer

Heavy multivitamin use may raise risk of advanced prostate cancer

Lower PSA cutoff would detect prostate cancer more often in men in their 40s

High BMI tied to treatment failure in prostate cancer


April 2007

Nerve-sparing laser approach to radical prostatectomy appears promising

Water diffusion tracks metastatic prostate cancer therapy response

MRI data useful in predicting insignificant prostate cancer

Ultraviolet radiation may protect against prostate cancer

Baseline PSA a poor predictor of lethal prostate cancer

Zoledronic acid for prostate cancer bone metastasis carries risk of renal toxicity

Metabolic syndrome associated with prostate cancer in African-American men

Loss of PTEN expression linked to prostate cancer metastasis


March 2007

Treatments for localized prostate cancer differ in side-effect profile

Annual zoledronic acid increases BMD in hypogonadal men with prostate cancer

Greater weight tied to prostate cancer mortality

PCA3 score best at predicting result of repeat prostate biopsy

Low-grade prostate cancer prediction model validated

Prostate mortality in blacks tied to healthcare access

Aggressive approach doubles high-grade prostate cancer survival

False-positive prostate cancer screen causes patient anxiety

Green tea plus painkiller slows prostate cancer

PSA test in mid-life predicts long-term risk of prostate cancer

PSA test in mid-life predicts prostate cancer in old age


February 2007

Pertuzumab extends survival for some prostate cancer patients

Low PSA does not rule out prostate cancer progression

Not all treatments for early prostate cancer equally effective: study

Satraplatin delays progression of advanced prostate cancer

Watchful waiting underutilized in men with low-risk prostate cancer

Nerve grafts may restore erectile function after prostatectomy

Age adjustment of PSA measures might improve prostate cancer screening

Prostatectomy approaches have similar continence impact

Obese men are more likely to be screened for prostate cancer

Selenium not linked to prostate cancer risk


January 2007

Low risk of prostate cancer seen in men with schizophrenia

Finasteride may distinguish between prostate cancer and benign disease

Survival rate highest with prostatectomy for localized prostate cancer

Improved nomogram helps gauge prostate cancer aggression

Early phosphodiesterase inhibitor use after brachytherapy aids erectile function

High-intensity focused ultrasound effective against high-risk prostate cancer

Prostate cancer treatment may shorten penis

Prostate cancer costs vary significantly by treatment type

Y chromosome may have role in prostate cancer


December 2006

Radical prostatectomy in older men not associated with greater excess mortality

Men with localized prostate cancer benefit from definitive treatment

Breast cancer family history raises prostate cancer risk in African Americans

Localized prostate cancer treatment lowers mortality in elderly men

Lower prostate cancer risk seen with metabolic syndrome

Decreased prostate cancer risk with NSAID use tied to genotype


November 2006

Diabetic men have a lower risk of prostate cancer

Myosin VI plays a key role in prostate cancer

Radiation after radical prostatectomy reduces recurrence rate, but not mortality

Dynamic contrast-enhanced magnetic resonance helps spot prostate cancer

Protein triggers new prostate cancer treatment

Metabolic syndrome a predictor of prostate cancer

PSA bounce after radiation for prostate cancer does not predict clinical failure


October 2006

Prostatectomy may help in highest-grade prostate cancer

GnRH agonist use for prostate cancer may up diabetes and heart disease risks

Tall, married men seen to have higher risk of prostate cancer

AZGP1 expression predicts metastasis after prostatectomy

Zoledronic acid ups bone mineral density in men receiving anti-androgen therapy

Alcohol intake does not affect prostate cancer risk


September 2006

Androgen deprivation therapy increases risk for diabetes, cardiovascular disease

Chronic inflammation tied to prostate cancer

Toremifene may help ward off prostate cancer

Biopsy of the prostate can be less painful

COX-2 expression in prostate cancer predicts recurrence

Increased risk of prostate cancer seen in rotating-shift workers

Angiogenin plays dual role in prostate cancer progression

Bicalutamide added to radiotherapy improves prostate cancer survival

PSA after treatment predicts survival in metastatic prostate cancer

Radical prostatectomy effective for some men with high-grade prostate cancer


August 2006

Chromosome 8 region linked to prostate cancer in African Americans

Targeted chimeric RNAs inhibit prostate cancer in murine model

Drug combo effective for prostate cancer cytoreduction before brachytherapy

Data support lower prostate specific antigen threshold for African American men

Hemoglobin drop a poor sign after androgen deprivation for prostate cancer

Family history of prostate cancer has little effect on prognosis

Altering dietary fatty acids slows prostate cancer growth in mice


July 2006

15% of men with prostate cancer undergo secondary chemotherapy

Bone scans not needed in men with low PSA after localized prostate cancer therapy

GI toxicity prolonged after prostate cancer irradiation

MUC1 vaccine may help slow prostate cancer after prostatectomy failure

Previous prostate radiation therapy linked to higher-grade bladder cancer

Prostate cancer vaccine improves disease-free survival

Radical prostatectomy for locally advanced prostate cancer feasible, effective

Hyperbaric oxygen may relief complication of prostate cancer therapy

Fear and misconception drive patients' choices for prostate cancer treatment


June 2006

Occult prostate cancer lymph node metastases tied to recurrence, mortality risk

UK'S NICE approves Sanofi's Taxotere for advanced prostate cancer

External radiation boosts brachytherapy control of prostate cancer

Obesity tied to disease recurrence after radiotherapy for prostate cancer

Urologist main determinant of hormone therapy use in prostate cancer

Folate intake may alter risk of advanced prostate cancer

Polymorphisms may influence survival in prostate cancer


May 2006

Modern cryotherapy an option for primary and recurrent prostate cancer

Nomogram predicts prostate cancer recurrence up to 10 years after surgery

Genitofemoral nerve grafts aid erectile function after prostatectomy

Androgen-deprivation monotherapy controls localized prostate cancer

Androgen deprivation therapy of prostate cancer lowers bone mineral density

First genetic marker of prostate cancer identified

Prostate cancer screening not supported for older men


April 2006

Surgery plus radiation does not control aggressive prostate cancer

GnRH therapy boosts diabetes risk in men with prostate cancer

Raloxifene acts against prostate cancer

Predictive model may improve assessment of prostate cancer risk

Histrelin subdermal implant effective against advanced prostate cancer

Testosterone levels rebound after androgen deprivation

Degarelix rapidly decreases testosterone in men with prostate cancer


March 2006

Confusion reigns in how men decide treatment for prostate cancer

Second-line therapy ineffective in hormone-refractory prostate cancer

'Androgen deprivation syndrome' tied to comorbidities, not therapy itself

Free PSA and hk2 enhance risk estimates of prostate cancer recurrence

Racial gap in prostate cancer survival due mostly to socioeconomic factors


February 2006

Alendronate prevents bone loss in men on androgen deprivation therapy

Age-adjusted PSA velocity may boost prostate cancer detection

Virus may cause prostate cancer, study hints

Prostate cancer harder to spot in obese men

Prostate re-screening interval could be safely extended for some

Depot delivery system maintains steady drug level in prostate cancer patients

Antioxidants of little benefit in preventing prostate cancer

Black men with highest prostate cancer risk have lowest screening rates

Genetic variants of IGF1 associated with prostate cancer risk

Algorithms for staging prostate cancer are improved with MRI

Long-term hormone therapy cost-effective for locally advanced prostate cancer


January 2006

Smoking linked to prostate cancer through hypermethylation of multiple genes

Statins improve outcome after brachytherapy for prostate cancer

Complexed PSA best for prostate cancer screening in black men: study

Palladium brachytherapy feasible as adjuvant treatment of early breast cancer

Prostate cancer screening may not reduce mortality

Hormone therapy for prostate cancer increases fracture risk

Biofeedback can reduce post-prostatectomy incontinence

Androgen deprivation affects memory in prostate cancer patients


December 2005

Cystoprostatectomy provides effective palliation for prostate cancer

Low serum testosterone levels associated with worse prostate cancer outcome

Prostate cancer not uncommon at PSA of less than 4 ng/mL

Serum Her-2/neu protein tied to prostate cancer progression

Androgen deprivation leads to bone loss in men with prostate cancer

Tyrosine kinase Ack1 plays role in prostate cancer development

Obesity increases risk of prostate cancer recurrence

DPPE added to chemo relieves pain in advanced prostate cancer

Satraplatin curbs hormone-refractory prostate cancer


November 2005

Long-term androgen deprivation beneficial for prostate cancer with high PSA

Digital rectal exam identifies prostate cancers with normal PSA

Herbal COX inhibitor acts against prostate cancer cells

Smaller prostate size associated with more aggressive cancers

Penile prosthesis aids life quality after prostatectomy

Prostate brachytherapy does not always lead to infertility

Antibody inhibits prostate tumor growth by Fc-independent mechanism

High-dose calcitriol potentiates docetaxel in advanced prostate cancer

Gene rearrangements often seen with prostate cancer


October 2005

High-dose strontium-90 brachytherapy effective for posterior uveal melanoma

Post-treatment PSA doubling time predicts prostate cancer-specific mortality

Single men with metastatic prostate cancer less likely to seek retreatment

Brachytherapy may change outlook for inoperable lung cancer

Biomarker for aggressive prostate cancer identified

FDA rejects Abbott prostate cancer drug Xinlay

Obesity increases prostate cancer recurrence risk

PSA doubling time points to prostate cancer outcome

Androgen deprivation beneficial in localized prostate cancer


September 2005

Post-prostatectomy fossa biopsy may be unnecessary

Gene mutation may raise prostate cancer risk in African Americans

Pomegranate extract promotes apoptosis of prostate cancer cells

Anti-tumor autoantibodies may improve accuracy of prostate cancer screening

Clusterin inhibitor promising against prostate cancer

Diet and exercise changes may slow prostate cancer

Statistical artifact may influence better prostate cancer outcomes

Some men with prostate dysplasia can be managed conservatively

MDM2 oncoprotein may predict prostate cancer metastasis

Calcitriol and NSAIDs together block prostate cancer cell growth


August 2005

PSA levels in young adulthood may predict prostate cancer risk

PSA screening lowers metastatic prostate cancer risk

Dietary pattern may increase prostate cancer risk

Brachytherapy adds to pediatric lymphoepithelioma therapy

LHRH peptide targets chemotherapy to ovarian cancer cells

Younger prostate cancer patients fare well with prostatectomy

Statin use linked to decreased risk of prostate cancer

Obesity associated with prostate cancer

Stat5 protein activation predicts early recurrence of prostate cancer

Testosterone treatment linked with prostate cancer

Postoperative radiotherapy useful for prostate cancer with capsular extension

Collagen method delivers siRNA to prostate cancer bone metastases

Antioxidant vitamin and mineral supplementation may help prevent prostate cancer

Racial variation in GSTP1 hypermethylation seen in prostate cancer


July 2005

Vaccine plus antiandrogen may be useful for prostate cancer with rising PSA

Risk factors for prostate cancer mortality after biochemical recurrence identified

Absorbable sling enhances early continence after radical prostatectomy

Prostate cancer hormone therapy may affect cognition

In prostate cancer treatment, quality of life better with radiation

PSA screening of asymptomatic men cuts risk of metastatic prostate cancer

Higher neuroserpin expression predicts worse outcomes in prostate cancer

No specific PSA value directly tied to prostate cancer risk

Extended NSAID use may cut prostate cancer risk

Prostate cancer radiotherapy does not raise bladder cancer risk


June 2005

Histone modification pattern predicts prostate cancer outcome

Cryosurgery effective palliation for endobronchial tumors

Expanded access to Xinlay for prostate cancer approved

Exercise improves sexual function after prostate cancer radiotherapy

Combination chemotherapy effective in hormone-refractory prostate cancer

Low expression of prostate cancer biomarker tied to progression, death

Gleason pattern combination helps grade prostate cancer


May 2005

Active surveillance obviates treatment for some men with prostate cancer

Androgen levels directly linked to breast cancer risk in young women

MMP-7 plays key role in prostate cancer-induced osteolysis

Overexpression of four genes distinguish prostate cancer from BPH

Testosterone stays low after stopping prostate cancer hormone therapy

New biomarker sensitive indicator of prostate cancer

Toremifene cuts prostate cancer risk in men with precancerous PIN

Radical prostatectomy in early prostate cancer improves 10-year outcomes

Circulating tumor cells predict metastatic prostate cancer survival

Salvage surgery good option after failed radiotherapy for prostate cancer

Stable course of localized prostate cancer supports conservative management

In utero exposure to estrogenic chemicals affects prostate growth in mice


April 2005

Stearoyl-CoA desaturase downregulated in prostate cancer

Longer screening intervals delay prostate cancer detection

Green tea may prevent prostate cancer in men at risk

MR spectroscopy aids in prostate cancer prognosis

Tamoxifen can reduce breast pain in prostate cancer patients

Testing during prostatectomy helps predict continence

Genetic protection from malaria may fuel prostate cancer in African-Americans

Prostate radiotherapy raises risk of rectal cancer


March 2005

Ethnicity, marital status affect treatment decisions in prostate cancer

Obesity may hasten prostate cancer diagnosis

Androgen deprivation for prostate cancer leads to metabolic disturbances

Long-term androgen deprivation for prostate cancer can be speedily reversed

Perineal radical prostatectomy useful for cancer in renal transplant recipients

US Medicare to cover prostate cancer drug

Brachytherapy for prostate cancer yields good long-term results

Men more likely to be screened for prostate cancer than colon cancer

MR method assesses prostate cancer aggressiveness noninvasively

High levels of vitamin E fractions linked to reduced risk of prostate cancer

Hormone therapy for prostate cancer affects cognition


February 2005

Finasteride use could cut prostate cancer deaths in US

Carotenoids may protect against prostate cancer

Modified docetaxel regimen more tolerable in hormone-refractory prostate cancer

High plasma folate levels may increase risk for prostate cancer


January 2005

Adjuvant therapy not indicated for low-risk prostate cancer patients

Low beta-catenin levels predict prostate cancer outcome

Obesity-related drop in PSA levels could mask prostate cancer

Plastic component boosts prostate cancer growth

MRI/CT planning may help prevent impotence after prostate radiotherapy

Diabetes associated with reduced risk of prostate cancer

Androgen-deprivation therapy for prostate cancer raises fracture risk

Dendreon prostate cancer drug fails to delay disease progression

Red wine may reduce prostate cancer risk

Dietary fats linked with prostate cancer aggressiveness


December 2004

"Biomarker roadmap" may help guide experimental prostate cancer therapy

"Watchful waiting" may be safe for carefully selected men with prostate cancer

PSA rise after radical prostatectomy helps predicts outcome

Adoptive immunotherapy effective in mice with metastatic prostate cancer

Low-fat diet feasible for prostate cancer patients

Transdermal estrogen: antiandrogen and osteoprotection for prostate cancer

New prostate cancer drug formulation wins FDA approval

Osteoporosis prevention neglected in men treated for prostate cancer

Ferromagnetic thermal ablation effective in locally recurrent prostate cancer

Green tea polyphenols inhibit IGF-1 signaling in prostate cancer model


November 2004

Radioactive iodine uptake seen after brachytherapy

Scale helpful in evaluating prostate cancer MRIs

New knowledge of androgen receptor modulation may alter prostate cancer therapy

Antisoma's telomere-targeting agent blocks experimental prostate cancer

Bicalutamide helpful in locally advanced prostate cancer


October 2004

Long-term prostatectomy outcomes better in African-American men

Blocking IGF1R gene makes prostate cancer cells vulnerable

Brachytherapy can preserve sexual function in men with localized prostate cancer

Osteoprotegerin best of proposed markers for prostate cancer bone metastases

Red wine consumption may lower prostate cancer risk

Docetaxel-containing regimens improve survival in advanced prostate cancer

Brachytherapy for prostate cancer sufficient without adjuvant treatment


September 2004

Lycopene plus vitamin E slows human prostate tumor growth in mice

IL-6 slows progress of prostate cancer tumors

Elderly blacks much less likely to be screened for prostate cancer

Androgen ablation response varies in metastatic prostate cancer

Rb gene deletion tied to prostate cancer onset

Urinary, bowel, sexual problems persist long after localized prostate cancer therapy

PSA no longer useful diagnostic marker of prostate cancer


August 2004

Obesity independently linked with poor outcome after prostate cancer surgery

MHC class I chain-related molecules may serve as biomarker for prostate cancer

Hepsin tied to progression of prostate cancer

Endorectal MRI useful for evaluating localized prostate cancer

Low-risk prostate cancer outcomes similar with observation or radiation therapy

Insulin-like growth factor I tied to prostate cancer risk

Brachytherapy inhibits in-stent neointimal hyperplasia in diabetics

Stat5 protein tied to prostate cancer virulence


July 2004

Antibody targets androgen-independent prostate cancer

Rate of PSA rise predicts death from prostate cancer after surgery

Phosphorylation inhibitors suppress prostate cancer bone metastases in mice


June 2004

Postoperative radiation therapy prolongs survival in prostate cancer patients

Onyvax says prostate cancer therapy shows promise

Balloon brachytherapy suitable alternative to standard breast cancer radiation

Adjuvant, salvage radiotherapy comparable after prostate cancer surgery

Docetaxel improves survival in hormone-refractory prostate cancer

Taxotere can increase survival in prostate cancer patients


May 2004

Gene marker may help spot prostate cancer metastases

Prostate cancer not rare among men with normal PSA levels

More evidence that diabetes may protect against prostate cancer

Endorectal coil MRI useful in detecting cancer recurrence after prostatectomy

Aberalix helpful in some advanced prostate cancer patients

Selenium levels inversely linked to risk of advanced prostate cancer

E-cadherin gene promoter polymorphism linked to hereditary prostate cancer


April 2004

Prostatectomy improves urinary tract symptoms in men with prostate cancer

Leading treatments for localized prostate cancer yield similar results

Soy metabolite shows novel anti-androgen effects in rats

Novel prostate cancer marker spots cancer when the biopsy is negative

Most low-PSA prostate cancers are clinically significant

Ejaculation does not raise prostate cancer risk

Urinary flow tied to prostate cancer brachytherapy outcome


March 2004

Prostate cancer therapy not tied to colorectal cancer risk

Early salvage radiotherapy treats "incurable" recurrent prostate cancer

Genetic profile points to prostate cancer outcome

Insulin-like growth factor tied to prostate cancer risk

Alternative antiandrogens effective after relapsed prostate cancer


February 2004

Low-fat diet boosts efficacy of androgen deprivation for prostate cancer in mice

New guidelines stress uniformity of clinical trials for relapsed prostate cancer

Aspirin use linked to lower prostate cancer risk


January 2004

Catheter-based brachytherapy after PCI is highly thrombogenic

Screening for prostate cancer leads to earlier detection

Androgen receptor blockade a potential therapy for ER-negative breast cancer

Age bias may influence treatment of localized prostate carcinoma

HHV-8 seropositivity linked with prostate cancer

Hormone therapy for prostate cancer may cause rapid bone loss

Antibody to p53 a marker for nonpalpable prostate cancer

10-year follow-up provides more accurate outcome of radiation for prostate cancer

Hepsin may represent new prognostic marker for prostate cancer


December 2003

Prostate zinc levels plus PSA levels aid in diagnosis of prostate cancer

Nuclear structure alterations predict outcome after radical prostatectomy for cancer

Earlier prostate cancer screening supported for black men

Increased androgen receptor expression leads to prostate cancer drug resistance

Androgen suppression for prostate cancer alters cognition somewhat

Older men may be over-screened for prostate cancer


November 2003

Decline in watchful waiting in prostate cancer

US approves new prostate cancer drug

Triple-drug regimen disappointing in hormone-refractory prostate cancer

Use of prostate brachytherapy has risen dramatically in US

Tomato powder, not lycopene, inhibits prostate cancer in rats

PCa-24 protein promising in prostate cancer detection


October 2003

UK says Casodex too risky in early prostate cancer

Complexed PSA no extra help in prostate cancer diagnosis

Lycopene helpful after orchidectomy for prostate cancer

Positive biopsy rate from prostate's affected side predicts cancer recurrence

Genetic polymorphism raises prostate cancer risk

Cialis may help erections after prostate surgery

Modern cryosurgery effective treatment for renal and prostatic tumors

Pintex study correlates Pin1 enzyme to severity of prostate cancer

Sildenafil does not promote prostate cancer growth in animal model


September 2003

Prostate cancer screening interval of 4 years misses few cancers

New method could help diagnose prostate cancer and other diseases

Outcome parameters, not procedure quantity, predict prostatectomy outcomes

New anti-prostate cancer compound gains FDA fast track status

Curative therapy benefits older men with localized prostate cancer

Prostate cancer risk highest when brother has the disease

Subcutaneous leuprolide delivers sustained effects in prostate cancer


August 2003

Vitamin D analog enhances radiation's ability to kill prostate cancer cells

Predictive nomogram for prostate cancer may reduce unnecessary biopsies

Some heavier men may have lower prostate cancer risk

High PSA levels no bar to prostate cancer surgery

Gene linked to hereditary prostate cancer may be involved in sporadic cases

African American prostate cancer patients receive fewer PSA tests


July 2003

Herbal COX-2 inhibitor induces prostate cancer cell apoptosis

Praecis says FDA extends review of prostate drug

Familial and sporadic prostate cancer cases share similar histories and outcomes

Telomerase inhibitor effective in prostate cancer cell lines

Smoking linked to increased risk of aggressive prostate cancer

Multiple genes may affect age at onset of hereditary prostate cancer

Androgen deprivation therapy may be overused for localized prostate cancer

Thapsigargin coupled to PSA substrate curbs experimental prostate cancer

Adding contrast improves ultrasound's ability to detect prostate cancer

Use of zinc supplements tied to possible increase in risk of prostate cancer


June 2003

Finasteride lowers risk of prostate cancer but increases risk of high-grade tumors

MRI with nanoparticles highly sensitive in detecting prostate cancer metastases

Annual prostate cancer screening tied to high overdetection rate

Prostate cancer survival improved with whole-pelvic radiation plus hormone therapy

Paraoxonase polymorphism confers increased risk of prostate cancer

Alpha-1 adrenergic blockade might be useful in treatment of prostate cancer


May 2003

Abnormal PSA test should be repeated before prostate biopsy

Biennial screening for prostate cancer sufficient when baseline PSA is low

Quality of care indicators developed for treatment of prostate cancer

Novel GnRH antagonist shows activity in men with prostate cancer

Biomarker combination linked to prostate cancer recurrence

Molecular markers point to radiotherapy outcome in prostate cancer


April 2003

Long-term evidence on prostate brachytherapy, cryoablation encouraging

Free PSA testing improves prostate cancer detection in men at high risk

Androgen suppression can be discontinued in some prostate cancer patients

Enzyme identified as potential therapeutic target in prostate cancer

Estrogen patches helpful in advanced prostate cancer

Quality of life not worsened by hormone-deprivation therapy after prostate brachytherapy

Prostate cancer more than twice as likely in obese men


March 2003

Leptin influences cellular differentiation and progression in prostate cancer

Increased risk of male breast cancer seen in prostate cancer patients

Prostate cancer now top male cancer in Britain

Patient age may not be relevant when selecting prostate cancer therapy

Imatinib plus paclitaxel reduces prostate cancer bone metastasis

Prostate cancer with nodal involvement may be curable with surgery

Predictors of PSA relapse after radiotherapy for prostate cancer identified

Smoking linked with increased risk of advanced prostate cancer

Green tea shows minimal efficacy against prostate cancer


February 2003

Endothelin-a receptor antagonist, atrasentan, fails in prostate cancer trial

Selenium supplementation may decrease DNA damage in prostate


January 2003

Adult body size not related to prostate cancer risk

Excess prostate cancer risk associated with high bone mass

Predictors of disease recurrence for high-risk prostate cancer identified

Older age predicts shorter survival with high-risk prostate cancer

Cytokeratin-positive cells predict distant metastases in prostate cancer patients

Sustained platelet activation observed after intracoronary brachytherapy

Prognosis of high Gleason score, low PSA prostate cancer surprisingly good

Salvage radiotherapy shows promise for PSA recurrence after prostatectomy

Radiofrequency appears superior to cryosurgery in preventing liver metastases


December 2002

Telomerase immunoreactivity of prostate tumors has diagnostic potential

FDA panel declines backing for Casodex to treat early prostate cancer

Hormone therapy before prostatectomy appropriate for stage T3 prostate cancer

Antigen-specific immunotherapy increases survival in mice with prostate tumors

Post-treatment PSA doubling time predicts prostate cancer-specific death

Brachytherapy for prostate cancer equally effective for blacks and whites

Net benefit of prostate cancer screening cannot be determined

Most therapies provide similar outcomes for early prostate cancer


November 2002

Aspirin and other NSAIDs do not appear to reduce prostate cancer risk

Excision plus brachytherapy may obviate mastectomy for recurrent breast cancer

Prophylactic use of alpha-blockers optimal after prostate brachytherapy

Failure of flutamide treatment in prostate cancer traced to EGF receptor signaling

Diet rich in flaxseed protects mice from prostate cancer


October 2002

BRCA2 mutation may increase prostate cancer risk

HER2 expression weak in primary prostate cancers

Low recurrence rate of breast cancer seen with brachytherapy

Vasectomy does not increase prostate cancer risk

Positive surgical margins significant predictor of recurrence in prostate cancer

Overexpressed protein tied to metastatic prostate cancer

FDA clears brachytherapy breast irradiation device

Algorithm helps predict lymph node metastases in prostate cancer

Zoledronic acid reduces risk of skeletal events with metastatic prostate cancer


September 2002

Infection with C. trachomatis may protect against prostate cancer

Brachytherapy causes iatrogenic shedding of prostate cancer cells

Catheter-based brachytherapy prevents stent restenosis in diabetic patients

Mutations in MSR1 gene linked to prostate cancer

Surgery and watchful waiting for early prostate cancer provide similar outcomes

Low-fat high-fiber diet does not lower PSA levels, prostate cancer risk


August 2002

Surgery, radiotherapy equivalent for localized prostate cancer

Local treatment may improve outcomes in advanced prostate cancer

Locally persistent prostate cancer can result in a late wave of metastases

Lymph node dissection essential for correct prostate cancer staging

New drug shows promise against hard-to-treat breast and prostate cancers

Bicalutamide reduces risk of prostate cancer progression

High calorie, fat, and calcium diet linked to higher prostate cancer risk

Younger prostate cancer patients at risk for treatment failure with radiotherapy

Estrogen receptor signaling modulates human prostate cancer telomerase activity

Nomogram accurately predicts likelihood of prostate cancer recurrence


July 2002

Androgen blockade may provide long-term control of localized prostate cancer

Complications of prostate cancer treatment more common than often reported

Radiotherapy for prostate cancer has little effect on urinary function

Adding androgen suppression to radiotherapy improves prostate cancer survival

Polyphenols in red wine induce apoptosis of prostate cancer cells

Avoidant coping increases stress of prostate cancer diagnosis

Cancer-associated antibody test could improve specificity of prostate screening

Prostate cancer overdiagnosis due to PSA screening "considerable"


June 2002

Selective screening based on family history misses most prostate cancers

Vasectomy not linked to prostate cancer

Ratio of cathepsin B to stefin A predicts node involvement in prostate cancer

High lycopene levels may protect against prostate cancer

Serial bone testing may detect fracture-prone prostate cancer patients


May 2002

Prostate cancers often missed on initial biopsy

Blacks more likely than whites to have prostate cancer recurrence

Oncoprotein shows promise as predictor of prostate cancer survival


April 2002

"Watchful waiting" approach to prostate cancer may benefit selected patients

Nerve-sparing prostatectomy recommended whenever possible

Vaccine elicits response in patients with advanced prostate cancer

High rate of lymph node metastasis found in clinically localized prostate cancer

Herbal supplement for prostate cancer contains indomethacin, DES and warfarin

Radiation implants for prostate cancer can move to lungs

PSA screening not associated with decreased prostate cancer mortality

Gene overexpressed in prostate cancer identified


March 2002

Daily NSAID use may reduce prostate cancer risk in older men

Initial androgen deprivation therapy for prostate cancer affects sexual function

Bone scan may be unnecessary for some men with prostate cancer

Tomato product intake may reduce prostate cancer risk

DES can prevent adverse bone effects of prostate cancer therapy


February 2002

Brachytherapy complements laser therapy in esophageal cancer palliation

Brachytherapy viable alternative to amputation for penile cancer

Prostate cancer trends in France began to improve in early 1990s

Vaginal brachytherapy as effective as whole pelvic radiation


January 2002

BioPince needle has pros and cons for prostate biopsy

FDA approves one-month formulation of leuprolide for prostate cancer

Prognostic factors identified for prostatectomy outcome in high grade cancer

Germline mutations in ribonuclease gene linked to prostate cancer

Enzyme prompts bone loss in prostate cancer

Vegetarian diet, stress management slows PSA rise in prostate cancer patients


December 2001

Bilateral orchiectomy declining in US men with prostate cancer

Xenogeneic antigen vaccine promotes vigorous response to prostate cancer

Increased needle biopsy sampling detects earlier stage prostate cancer

Possible tumor suppressor gene linked to prostate cancer

Tomato sauce consumption decreases DNA damage in prostate cancer patients

Supplemental selenium may reduce prostate cancer risk


November 2001

FDA cautions about inadequate prostate cancer treatment at Florida facility

After negative prostate biopsy, one more biopsy usually sufficient

GSTP1 methylation level discriminates malignant from benign prostate disease

Routine digital rectal examination uninformative after prostate radiotherapy

Microwave therapy shows promise as treatment for prostate cancer

External radiation for prostate cancer has low impact on near-term quality of life

Whole-pelvic radiation advantageous in prostate cancer with lymph node risk

Most men maintain erectile function after brachytherapy


October 2001

Herbal prostate supplement may cause bleeding

Prostate-specific gene therapy induces apoptosis in prostate cancer cells

High-normal PSA level in middle age indicates elevated risk of prostate cancer

Biennial PSA testing does not increase risk of nonlocalized prostate cancer


September 2001

High calcium intake may boost risk of prostate cancer

Proxima breast cancer brachytherapy device cleared in Canada

Prostate cancers that occur with low PSAs are usually clinically significant

Nomogram helps predict outcome of prostate brachytherapy

Casodex approved in UK for early-stage prostate cancer

Bicalutamide reduces risk of prostate cancer progression

Endocrine-related outcomes similar after surgery or hormone therapy for prostate cancer


August 2001

PSA rise and positive biopsy after brachytherapy may not signal cancer

Prognostic biomarkers identified for prostate cancer

Exisulind improves PSA parameters of men with recurrent prostate cancer

Age-related increases in DNA damage favor development of prostate cancer

Occult spinal cord compression risk can be predicted in prostate cancer patients

Low-fat, flaxseed-supplemented diet may benefit prostate cancer patients

Implant Sciences receives EU approval for prostate cancer brachytherapy seeds

Draxis to market palladium-103 brachytherapy implant in Canada


July 2001

PSA is superior to free-to-total PSA ratio in predicting prostate cancer

Brachytherapy or enucleation for choroidal melanoma yield similar survival rates

Cryoablation reasonably effective and safe for recurrent prostate cancer

Debiopharm wins FDA approval for long-acting prostate cancer therapy


June 2001

Brachytherapy not innocuous for patients with localized prostate cancer

Hormone therapy decreases bone mass in prostate cancer patients

Amgen, Praecis present promising phase III data for prostate cancer treatment

Eating fatty fish may reduce prostate cancer risk


May 2001

Bisphosphonates might reduce bone metastasis in prostate cancer patients

Socioeconomic status linked to prostate cancer incidence in the PSA era

Matritech, Johns Hopkins identify a new prostate cancer marker


April 2001

Prostate cancer nomograms accurate, but effect on decisionmaking unknown

Nerve grafts help maintain erectile function following prostatectomy

Elevated leptin levels associated with increased risk of prostate cancer

Sensitive bone formation marker for prostate cancer metastasis identified

Immediate radiotherapy benefits prostatectomy patients at risk for recurrence

Predictors of biochemical failure after radical prostatectomy identified

Prostate cancer vaccine strategy yields promising results

Use of brachytherapy not supported by published data

Large study of early prostate cancer launched in the UK

Bicalutamide reduces risk of prostate cancer progression by 43%

High dietary boron linked to reduced risk for prostate cancer

Gene identified that may be target for prostate cancer vaccine


March 2001

BRCA2 mutation carriers have an increased risk of prostate cancer


February 2001

FDA clears two immunoassays for prostate cancer

Anti-PSCA antibodies show promise as prostate cancer treatment

Erectile dysfunction risk unrelated to type of prostate cancer treatment

Prostate tumor ablation technique uses implanted magnetic rods

Prostate biopsy affects patient well-being before the procedure

New prostate cancer test promising in early study


January 2001

ProstaScint scans predict prostate cancer recurrence and metastases

FDA grants priority review to Praecis Pharmaceuticals' prostate cancer drug

Prednisone drug of choice for progressive hormone-resistant prostate cancer


November 2000

Adjusted PSA levels useful in detecting prostate cancer


October 2000

Short-course hormone therapy does not benefit low-risk prostate cancer patients

Radiation therapy less costly than surgery for early prostate cancer

Long-term androgen suppression plus radiation increases prostate cancer survival

FDA approves component of Endocare's cell-freezing system for prostate cancer

Lymph node dissection can be omitted in subset of prostatectomy cases


September 2000

Prostate cancer cell growth inhibited in men on diet, exercise program

Elevated p53 levels bring worse prostate cancer prognosis

Percent free PSA increases specificity of prostate cancer detection

Visual examination of prostate tissue predicts recurrence after prostatectomy

Hereditary prostate cancer linked to other malignancies

COX-2 inhibition suppresses prostate cancer in experimental model

Androgen suppression unnecessary for some men with localized prostate cancer

Herbal mixture can reduce PSA levels in men with prostate cancer

Lidocaine safe, effective for topical anesthesia in transrectal prostate biopsy


August 2000

Introduction of p53 suppresses growth, metastasis of prostate cancer in mice

Experimental prostate cancer growth slowed by pHyde gene therapy

FDA clears Nucletron's SPOT imaging software for prostate seed implantation


July 2000

Percent free PSA, not age-specific cutoffs, sensitive in detecting prostate cancer

More extensive biopsy protocol improves prostate cancer detection rate

Androgen receptor gene variation predicts prostate cancer recurrence in low-risk men

Computerized tool detects early prostate cancer

Genentech licenses UroGenesys prostate cancer antigen

AxCell, Institutes for Systems Biology to collaborate on prostate cancer research

Seminal vesicle-sparing radical prostatectomy maintains urinary continence

Stilbestrol effective as salvage therapy for refractory prostate cancer

Immunex licenses UroCor antigens for prostate cancer research

Chromosomal gains correlate with prostate cancer progression after surgery


June 2000

Brachytherapy yields excellent long-term results in prostate carcinoma

Physicians likely to recommend prostate cancer treatments in their specialty

Loss of expression of androgen-receptor isoform detected in colon cancer

Several loci identified as possible hereditary prostate cancer markers

Draxis unit gets brachytherapy patent

Vegan diet may cut risk of prostate cancer

Myriad's prostate cancer finding boosts stocks

Circulating neuroendocrine marker improves prognostic assessment in prostate disease


May 2000

BCG treatment for bladder cancer raises PSA in absence of prostate cancer

Chinese herbal remedy holds promise for prostate cancer

New test predicts later metastasis of initially controlled prostate cancer

Laparoscopy permits more precise dissection during radical prostatectomy

Leuprolide implant provides successful palliative therapy for prostate cancer

Aggressive treatment for early prostate cancer cost -effective


April 2000

Older age is not a reason to delay prostate cancer treatment

Deferred endocrine therapy for prostate cancer yields high rate of morbidity

Doxazosin cytotxic to prostate carcinoma cell lines

Cause of death often misreported for prostate cancer patients

Aggressive prostate cancers form microcirculatory networks

Human glandular kallikrein aids identification of tumor stage in prostate cancer

Prostate-specific antigen bounce common after radioactive seed implantation


March 2000

Carbohydrate-based vaccine benefits prostate cancer patients

Suramin reduces pain, delays progression in hormone-refractory prostate cancer

Prolonged combined androgen blockade may increase survival of prostate cancer patients

Free PSA percentage effective for prostate cancer detection in black men

Decline in prostate cancer mortality supports benefit of early PSA screening

OCs may protect against ovarian cancer in part via direct antiandrogen effects


February 2000

FDA approves Syncor's palladium "seeds" for prostate cancer treatment


January 2000

Erectile dysfunction likely after radical prostatectomy for prostate cancer

Prostatectomy, radiation equally effective in treatment of low-risk prostate cancer

No link found between vasectomy and prostate cancer

PSA nadir of 0.2 ng/mL or less after irradiation represents cure of prostate cancer

Vegetables lower prostate cancer risk


December 1999

PSA level predicts prostate growth in patients with benign prostatic hyperplasia

Cryosurgery and video MRI eradicates renal cancer

FISH analysis predicts prostate cancer progression

Immediate hormonal therapy superior to observation after surgery for node-positive prostate cancer


November 1999

Biochemical failure does not predict survival after radical prostatectomy

Higher surgical volumes bring better prostatectomy outcomes

Equal outcomes seen with radiation or surgical therapy for prostate cancer

Smoking history adversely affects potency after prostate cancer treatment

Beta-carotene supplements may decrease prostate cancer risk in men with low levels


October 1999

Genetically engineered prostate cancer vaccine activates entire immune system

Consistently normal PSA levels suggest cure after radiation for prostate cancer

Endorectal MRI may aid in identifying high-risk men with prostate cancer

Digital exam, imaging unnecessary if PSA undetectable after prostatectomy

Preoperative percent free PSA a predictor of pathologic outcome after radical prostatectomy


September 1999

Chromosome 8 alterations linked to prostate cancer progression

Prostate cancer risk affected little by fat intake

Anti-bcl-2 ribozyme effective against hormone sensitive, resistant prostate cancer in culture


August 1999

Percentage of free PSA identifies prostate cancer risk in subset of men


July 1999

Antioxidant vitamins inhibit role of androgens in prostate cancer development

Outcome better with adjuvant rather than salvage radiation after prostatectomy

Bicalutamide as effective as maximum androgen blockade in treating advanced prostate cancer


June 1999

Mitoxantrone, prednisone combination effective for end-stage prostate cancer

Apoptosis markers help predict response to radiotherapy in patients with localized prostate cancer

NCI issues 5-year plan for prostate cancer research

High-flux dialysis decreases levels of prostate cancer marker


May 1999

Incidence of aggressive prostate tumors increasing in the Netherlands

Bone loss seen with androgen suppression therapy for prostate cancer

Overall mortality rate in US for prostate cancer reported


April 1999

Massachusetts hospital acknowledges 20 prostate biopsies misread between 1995 and 1997

Combination of total PSA, percent free PSA indicates risk of prostate cancer

Soy components reduce growth, metastasis of human prostate cancer cells in murine studies

E-cadherin expression appears to indicate progression of prostate cancer

Growth hormone implicated in increased prostate cancer risk among African Americans

Endothelin-receptor antagonist reduces pain of advanced prostate cancer

ASTRO issues guidelines on radiation therapy for prostate cancer

Neoadjuvant androgen ablation seems to add little to prostatectomy outcome

Androgen receptor expression of predictive value in patients with advanced prostate cancer


March 1999

Suramin may be useful in a subset of patients with refractory prostate cancer

Radical prostatectomy in node-positive prostate cancer appears beneficial

Race not an independent risk factor for positive prostate biopsy

Scotia to evaluate Foscan for lung, prostate cancers

Energy restriction reduces prostate tumor growth in rats

Amgen licenses rights to phase III prostate cancer drug

Tumor grade best predictor of outcome following radiotherapy for prostate cancer

Molecular mechanisms involved in prostate cancer development identified


February 1999

Survival advantage seen with initial radiotherapy for localized prostate cancer


January 1999

Prostate cancer progresses earlier, more likely to recur in African Americans

Conformal radiation of prostate reduces risk of bowel side effects

Digital exam and biopsy do not accurately gauge extent of prostate cancer

Age a stronger predictor of curable prostate cancer than PSA

Sildenafil ineffective in patients following non-nerve-sparing radical prostatectomy