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Types of Cancer > Skin Cancers > Melanoma > News
September 2009
New gene-targeted drug offers hope for melanoma patients
Melanoma "epidemic" may simply represent diagnostic drift
August 2009
Antioxidants not linked to melanoma risk
May 2009
Serum HU177 levels prognostic in primary melanoma
Modified herpes virus shows promise against metastatic melanoma
Pegylation does not improve tolerability of interferon alfa-2b for melanoma
April 2009
Non-clinical factors affect rates of sentinel node biopsy in melanoma
March 2009
Multi-marker test helps diagnose melanoma
Potential molecular prognostic markers for cutaneous melanoma identified
February 2009
Parkinson's disease and melanoma may share genetic components
Link between moles and melanoma risk similar worldwide
Carboplatin, paclitaxel, bevacizumab combination promising for stage IV melanoma
January 2009
Low estrogen receptor expression in melanoma reflects poor prognosis
Shorter interferon course may be adequate after melanoma resection
Chemotherapy enhances vaccine-induced anti-melanoma immunity
Skin cancer doesn't lower prostate, breast, and colorectal cancer risk
December 2008
Ipilimumab helpful in metastatic melanoma
IL-12 gene transfer by electroporation promising for melanoma
October 2008
Immunoembolization safe, promising for liver metastases from uveal melanoma
Dacarbazine-interferon combination promising in metastatic melanoma
Outcomes of melanoma seem no worse in transplant recipients
Melanogenesis inhibition sensitizes melanoma cells to radiotherapy
September 2008
Gene variant for vitamin D receptor linked to melanoma
Sentinal node biopsy warranted in some cases of thin melanoma
August 2008
Volatile organic compounds differentiate skin cancer from healthy skin
Polarized CD4+ T cells rid mice of melanoma
July 2008
Radioimmunotherapy targets metastatic melanoma lesions in phase I trial
June 2008
NSAIDs offer no protection against melanoma
KINK-1 increases melanoma sensitivity to chemotherapy
High melanoma incidence seen in methotrexate-treated rheumatoid arthritis
Tumor suppressor ARF inactivated in human melanoma
May 2008
Interferon benefits patients with early stage III melanoma
Targeting N-cadherin boosts melanoma response to chemotherapy
Sorafenib plus dacarbazine shows promise in advanced melanoma
April 2008
Melanoma survival worse with scalp or neck involvement
Caffeine protects mice against UV-induced skin cancer
March 2008
Heat shock protein 90 a promising target of uveal melanoma therapy
February 2008
Melanoma vaccine study misses primary goal
Osteopontin expression associated with melanoma outcome
January 2008
"Ugly duckling" sign identifies most malignant melanomas
Researchers identify melanoma-initiating cells
Psychoeducation no aid to melanoma survival
December 2007
Biochemotherapy boosts response but not survival in metastatic melanoma
November 2007
Optical tomography may help spot malignant melanoma
September 2007
IL-2 may benefit some patients with refractory metastatic melanoma
Drug combination active against uveal melanoma cells
Platelet growth factor linked to redness in melanoma
July 2007
Familial melanoma monitoring worthwhile
Lomeguatrib does not improve temozolomide treatment of metastatic melanoma
Capsule endoscopy identifies small bowel melanoma metastases
Interferon adjuvant thriftier in some melanoma patients
June 2007
Melanoma immunotherapy promising with low-dose interferon
May 2007
Diets high in meat linked with greater skin cancer risk
Stereotactic radiosurgery improves survival after melanoma brain metastases
Colon cancer a risk for uveal melanoma patients and their relatives
Melanin content of hair predicts risk for melanoma
April 2007
Melanoma in children and teenagers differs from that in young adults
SEER-based classification improves prediction of outcomes for melanoma
Survival of patients with cutaneous melanoma improved over past 25 years
New biomarker, therapeutic target for melanoma "truly exciting"
February 2007
Women's mortality from genital skin cancer triple compared with men's
January 2007
One-time melanoma screening of older patients cost-effective
Fast growing melanomas show distinctive features
Post-excision lymphatic mapping feasible after extensive melanoma surgery
December 2006
TANGO inhibits malignant melanoma tumors
November 2006
Melanoma thickness not seen related to time to diagnosis
T cell therapy helpful in metastatic melanoma
Test predicts aggressive choroidal melanoma
Burn injuries not seen to raise risk of skin cancer
September 2006
Melanoma treatment based on sentinel-node biopsy may prolong survival
Malignant melanoma increased before Parkinson's diagnosis
Custom antibody boosts anti-melanoma drug action in mice
August 2006
Modified autologous lymphocytes promote melanoma regression
Skin resurfacing reduces risk of actinic keratoses and skin cancer
Questionnaire at routine office visit helps estimate melanoma risk
Choroidal nevus size predicts transformation to melanoma
July 2006
Neoadjuvant chemotherapy may improve survival in stage III melanoma
High skin cancer risk in transplant recipients calls for heightened vigilance
Education program improves melanoma screening in men
June 2006
Blacks, Hispanics present with more advanced melanoma than whites
Radiotherapy may preserve eyes with large uveal melanomas
High-fat diet does not increase skin cancer risk
Parkinson's disease, not levodopa, linked to melanoma
April 2006
Surgery plus immunotherapy for metastatic melanoma prolongs survival
Recurrent melanoma more common than previously thought
Early PET scans no help in detecting occult melanoma metastases
March 2006
Genus beta HPV types implicated in skin cancer
February 2006
Autoimmunity suggests better response to interferon for melanoma
January 2006
Melanoma rates increasing among Hispanics
New vaccine regimen feasible for metastatic melanoma
Melanoma risk only partially associated with sun exposure
December 2005
Survivin expression tied to malignant melanoma outcome
Risk of second malignant melanoma is high
NSAIDs may protect against skin cancer
"Solarscan" differentiates melanoma from benign lesions
November 2005
Risk of skin cancer increased in rheumatoid arthritis patients
PET/CT imaging useful in detecting and staging choroidal melanomas
October 2005
High-dose strontium-90 brachytherapy effective for posterior uveal melanoma
Familial and non-familial melanomas are similar
Melanoma and other non-AIDS defining cancers on the rise
Melanoma risk with gene mutation lower than previously thought
Wide excision can avoid need for radiation with desmoplastic melanoma
ZymoGenetics melanoma drug wins orphan drug status
September 2005
Renal transplant recipients face higher melanoma risk
August 2005
Sentinel lymph node status predicts melanoma recurrence
Basal, squamous cell skin cancers increasing among young people
Pediatric melanoma rates continue to rise
Study suggests increased rates of melanoma are due to overdiagnosis
July 2005
Etanercept RA therapy does not boost skin cancer risk
Genetic polymorphism associated with melanoma risk
Occupational exposure to radiation raises skin cancer risk
MITF oncogene amplified in malignant melanoma
June 2005
Thick melanomas often nodular subtype in the US
Childhood cancer survivors treated with radiotherapy at risk of skin cancer
Radiotherapy for perineural spread of skin cancer to brain may extend survival
May 2005
Choroidal melanoma treatment not linked to excess risk of second cancers
April 2005
Mutant B-Raf tied to melanoma growth
Lymphodepleting T cell therapy continues to show promise against melanoma
March 2005
Type VII collagen needed for Ras-driven skin cancer
Melanoma may behave differently in children than in adults
February 2005
BRAF mutations linked to melanoma development, in zebrafish
Sunlight-related melanomas inherently less aggressive
Postoperative radiotherapy beneficial in primary head/neck mucosal melanoma
December 2004
TNF-based isolated limb perfusion is procedure of choice for advanced melanoma
Stress accelerates UV-induced skin cancer in mice
Early melanomas often evolve over time
Gene mutations may increase melanoma susceptibility by impairing DNA repair
November 2004
Melanoma patients helped by novel drug: Pfizer
CXCR3 expression on CD8 cells linked to survival in stage III melanoma
Complete response achievable with limb perfusion for unresectable melanoma
Pregnancy does not raise malignant melanoma mortality
Malignant melanoma outlook improving in Sweden
October 2004
Ultraviolet A radiation does not initiate melanoma
Circulating tumor cells prognostic in cutaneous melanoma
Melanoma outcomes often worse for nonwhite patients due to delayed diagnosis
September 2004
Breast cancer associated with melanoma risk, and vice versa
Investigational drug fails to improve survival in melanoma metastasized to liver
Curcumin displays strong anti-melanoma effects
August 2004
PET better than standard methods at detecting recurrent melanoma
Antibody induces immune response to malignant melanoma
Destroying normal melanocytes prompts attack on melanomas
July 2004
Basement membrane glycoprotein inhibits melanoma spread
June 2004
Dermoscopy useful in melanoma screening
May 2004
Metastatic patterns in ocular melanoma becoming clearer
Steroid use linked to increased risk of skin cancer, lymphoma
April 2004
Tumor necrosis factor aids melanoma chemotherapy in experimental model
Completion lymphadenectomy needed for all positive melanoma SLN biopsies
Atopic dermatitis unrelated to nonmelanoma skin cancer risk
FDA expands access to experimental melanoma drug
March 2004
Topical DNA oligonucleotide may reduce risk of skin cancer
February 2004
Therapeutic vaccine beneficial in clinical stage III melanoma
Lymphatic density predicts melanoma metastasis
Wider excision margin for high-risk melanoma curbs recurrence but not mortality
January 2004
New gene therapy approach targets disseminated melanoma
December 2003
Low-dose interferon does not improve survival of high-risk melanoma
November 2003
Childhood radiotherapy rarely tied to subsequent melanoma
Immune system challenge reduces risk of melanoma
Skin cancer link to other malignancies stronger in blacks
Melanoma vaccine with GM-CSF elicits strong response in phase II trial
Melanoma incidence and mortality trends declining in northern Europe
October 2003
Retinoid use reduces skin cancer risk in PUVA-treated psoriasis patients
Molecular analysis of archived lymph nodes predicts melanoma outcomes
Selenium may raise risk of squamous cell skin cancer in at-risk individuals
September 2003
Post-transplant skin cancers differ from others
New melanoma vaccine increases antitumor immunity
August 2003
Melanoma survival may be worse when foot or ankle is involved
S-100-beta levels not prognostic in uveal melanoma
July 2003
Signs and symptoms of primary melanoma predict depth of the lesion
June 2003
Dramatic rise in conjunctival melanoma noted among men over last 30 years
Ultraviolet light-inducible mutations very common with hereditary melanomas
May 2003
Sentinel node biopsy indicated for thin melanomas of Clark level III or greater
Melanoma incidence has doubled in Germany over past decade
April 2003
Glutamate protein implicated in melanoma
Melanoma prognosis unaffected by pregnancy
March 2003
Detection of circulating melanoma cells does not improve prognostic assessment
Melanoma mortality greater in UK than in Australia
Moles unlikely to transform into melanomas
Adequate follow-up contributes substantially to survival of melanoma patients
Some radiologic technologists at increased risk for melanoma
February 2003
Survivin gene expression in lymph nodes prognostic in melanoma patients
January 2003
Sentinel node with highest isotope count may not contain melanoma metastases
Nitric oxide may contribute to melanoma progression via MMP upregulation
Sentinel lymph node mapping safe and reliable for melanoma of head and neck
Vitamins/carotenoids not likely to protect against squamous cell skin cancer
Success reported in early trial of melanoma gene therapy vaccine
Mitogen-activated protein kinase triggered early in melanoma progression
December 2002
Melanoma can clinically mimic seborrheic keratosis
Therapeutic vaccine for disseminated melanoma prolongs survival
Survival after melanoma surgery unaffected by surgeon's specialty
November 2002
Dermatoscope plus computer imaging can yield rapid melanoma diagnosis
Adoptive T cell therapy effective against metastatic melanoma
October 2002
Wide excision margins yield no survival benefit for thin melanomas
Age and gender affect efficacy of chemotherapy for melanoma
Melanoma screening should target men over 50 years of age
Autologous peptide vaccine produces response in some cases of metastatic melanoma
Late recurrence of melanoma to be expected in significant portion of patients
September 2002
Peptide sensitizes melanoma cells to chemotherapy-induced apoptosis
Melanoma patients respond to T-cell transplant after lymphodepletion
Allogeneic stem cell transplant induces regression in metastatic melanoma
August 2002
Location and subtype of nonmelanoma skin cancer predicts risk of spread
Low serum HLA-DR predicts disease progression with early-stage melanoma
July 2002
Statin increases melanoma sensitivity to doxorubicin by augmenting apoptosis
Radiotherapy plus thermotherapy provides good local control of uveal melanoma
US grants orphan drug status to melanoma vaccine
Galectin-9 linked to less aggressive malignant melanoma
Malignant melanoma more aggressive in HIV-positive patients
Sunscreen use not tied to malignant melanoma
June 2002
Cutaneous melanoma in children requires early diagnosis and treatment
Rapid squamous cell skin cancer growth seen in HIV-infected patients
Celecoxib may help prevent skin cancer
Expression of inherited form of melanoma varies by geographic location
Temozolomide plus thalidomide well tolerated in melanoma patients
Cancer deaths due to melanoma seen increasing in Spain
Thin melanomas with extensive regression show increased metastatic potential
Mutations of BRAF gene linked to malignant melanoma
Vaccination prolongs relapse-free period in patients with advanced melanoma
May 2002
Parotidectomy often needed in aggressive head and neck skin cancers
Antisense therapy overcomes melanoma chemoresistance factor
Australia unveils melanoma detection device
Biochemotherapy extends survival in metastatic melanoma
April 2002
Little benefit seen with adjuvant interferon-alpha for malignant melanoma
March 2002
Skin cancer rates soaring in British men
Melanin density inversely tied to skin cancer risk in Caucasians
Small choroidal melanomas successfully eradicated with cryotherapy
February 2002
Novel combination chemotherapy regimen effective for squamous skin cancer
Antigenics wins fast-track designation for melanoma vaccine
January 2002
Histamine enhances effectiveness of interleukin-2 against melanoma
November 2001
Microphthalmia transcription factor is a marker of malignant melanoma
Melanoma vaccine containing heat-shock protein shows promise
September 2001
Cyclosporin increases skin cancer risk in PUVA-treated psoriasis patients
Melanoma model demonstrates damage from early sunburn
Expression of Id1 protein associated with early melanoma development
Melanoma relapse may be mediated by changes in extracellular matrix
July 2001
Confocal scanning laser microscopy shows promise in detecting amelanotic melanoma
Outpatient regimen of intravenous IL-2 promising for metastatic melanoma
Brachytherapy or enucleation for choroidal melanoma yield similar survival rates
May 2001
Sex, age affect risk of malignant melanoma
April 2001
High-dose IFN alpha-2b increases survival in resected high-risk melanoma
March 2001
Tumor vaccine boosts prognosis in melanoma patients
Melanoma, cancer of testis, colon linked to work-related radiation exposure
Reciprocal risk increase seen between melanoma and non-Hodgkin's lymphoma
February 2001
Computerized dermoscopic technique may improve diagnosis of melanoma
Ki-67 may be marker for metastasis in primary melanoma
Skin cancers in hidden locations thicker than "public" melanomas
Mutant herpes virus causes cell death in metastatic melanoma
Genetic factors may be involved in multiple melanomas
November 2000
Antisense BCL2 sensitizes advanced melanoma to dacarbazine therapy
Avax's melanoma vaccine M-Vax appears promising for stage IV disease
October 2000
Placebo-controlled trials needed for interferon alpha treatment of cutaneous melanoma
Interval lymph nodes may contain metastatic disease in patients with melanoma
Interleukin-2 not beneficial for patients with advanced metastatic melanoma
Schering's Intron A may be better than Progenics' GMK vaccine for melanoma
Large congenital melanocytic nevi increase risk of melanoma and neurocutaneous melanocytosis
Variants in pigmentation gene found to be risk factors for skin cancers
September 2000
Survival unaffected with smaller resection margin in melanoma surgery
August 2000
Cyclopamine blocks Sonic hedgehog signaling; may treat skin cancer
Melanoma cell growth inhibited by contact with fibrillar collagen
Genes expressed at high levels in metastatic melanomas identified
July 2000
AVAX launches new skin cancer vaccine in Australia
Skin cancer surveillance advised for kidney transplant recipients
Most melanoma patients detect their own cancer
June 2000
Young women at increasing risk for melanoma
Ultrasound detects melanoma metastases missed by clinical examination
May 2000
IL-2 plus histamine improves overall survival in metastatic melanoma patients
HPV in melanoma tumors associated with poor outcome
Maxim's Maxamine improves survival in patients with advanced skin cancer
Inhaled interleukin-2 reduces lung metastases from malignant melanoma
February 2000
Beta-carotene supplementation does not protect men against skin cancer
December 1999
New follow-up recommendations for malignant melanoma published
November 1999
Squamous-cell skin cancer tied to poor outcome in subsequent cancer
August 1999
Controversy surrounds use of sentinel lymph node biopsy in melanoma patients
June 1999
National Cancer Institute awards melanoma research grant to Wistar
Tamoxifen does not improve treatment of advanced malignant melanoma
May 1999
Immunotherapy produces remission in subset of patients with in-transit melanoma
Melanoma recurrence risk low with negative results on sentinel lymph node biopsy
March 1999
Identification of melanoma gene opens doors to screening, treatment
FDA advisers vote against approval of temozolomide for metastatic melanoma
February 1999
Anatomic site and thickness related in cases of primary melanoma
immunosuppressive therapy linked to skin cancer
Physician-detected melanomas are thinner and more rapidly biopsied
Survival rates for children with melanoma similar to adult survival rates
January 1999
High incidence of skin cancer confirmed in heart transplant recipients