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Types of Cancer > Gastrointestinal Cancers > Colorectal Cancer > News
November 2009
Therapeutic delay reduces survival of rectal cancer, but not colon cancer
Iron infusions do not cut blood transfusions with colorectal cancer surgery
October 2009
NSAIDs linked to lower mortality after colorectal cancer diagnosis
Videorecording may improve colonoscopy performance
First-line chemo for colon cancer should not include planned discontinuation
Diet supplements do not affect colorectal cancer markers
August 2009
Aspirin cancels benefits of HRT for colorectal cancer
CT colonography not useful for triage of positive fecal blood tests
CORRECTION: Taking aspirin after colorectal cancer diagnosis may improve survival
Common mutations linked to adverse colorectal cancer outcomes
Family history of breast cancer may raise colorectal cancer risk
Delayed return of fecal blood tests may miss colorectal cancers
Cetuximab more cost effective for wild-type KRAS colorectal cancers
July 2009
Most primary care doctors discuss only some colon cancer screening methods
Capsule endoscopy lacks sensitivity of colonoscopy
Intensive postop follow up benefits early-stage colon cancer patients
June 2009
CT colonography may be appropriate for surveillance of high-risk patients
Primary tumor resection unnecessary in most metastatic colorectal cancer cases
May 2009
Medicare will not pay for "virtual" colonoscopy
April 2009
Folate fortification may raise risk of colon cancer
CT colonography may yet challenge colonoscopy
Coffee does not appear to reduce risk of colorectal cancer
Colorectal cancer screening decisions should consider life expectancy
Fecal occult blood screening may help reduce colorectal cancer mortality
Thousands of colon cancers averted with screening colonoscopy in Germany
Cetuximab useful for some patients with unresectable colorectal cancer
March 2009
Colorectal cancer risk increased with endometrial cancer
Chemotherapy may benefit metastatic colon cancer patients
Inflammatory bowel disease not linked to cervical abnormalities
New guidelines for colon cancer screening released
February 2009
Reminders may increase colon cancer screening rates
Screening CT colonography and colonoscopy similarly effective
Adding cetuximab to standard therapy worsens outcomes in colorectal cancer
January 2009
Fluorouracil-based adjuvant therapy may cure colon cancer
Lymph node ratio predicts colorectal cancer survival
Overexpression of HER-2 not prognostic in colorectal cancer
FDG-PET helps assess recurrent colon cancer
KRAS testing before anti-EGFR therapy in metastatic colorectal cancer urged
Skin cancer doesn't lower prostate, breast, and colorectal cancer risk
December 2008
Low CEA after resection of colorectal liver metastases predicts better survival odds
Improved stool DNA test helps spot colorectal cancer
Colonoscopy cuts deaths from left-sided colon cancers only
Tumoral LINE-1 hypomethylation tied to poorer colon cancer prognosis
November 2008
Not cost-effective to remove small colon polyps found on screening CT
Calcium to magnesium ratio important in colorectal cancer prevention
Multimodality therapy can cure unresectable colorectal cancer
October 2008
K-ras mutations with colon cancer predict no benefit with cetuximab
New tool helps patients decide on genetic testing for colorectal cancer
Narrow band imaging does not improve colonoscopy miss rate
Folate curbs p53-mutated colon cancer
Metabolic syndrome raises colorectal cancer risk: study
Surgery viable option for some colorectal cancers with peritoneal disease
Colorectal cancer screening guidelines revised
September 2008
Adiponectin gene variant tied to reduced risk of colorectal cancer
Colorectal cancer screening increased in older Americans
Colon cancer outcomes worse at hospitals with high Medicaid percentages
Benefit of flexible sigmoidoscopy limited to distal colon
Sensitivity of CT colonography high in detecting large lesions
BMI and weight gain unrelated to colon cancer recurrence risk
Autofluorescence videoendoscopy improves colon polyp discovery
Follow-up care lacking for many older colon cancer survivors
Automated quantification of fecal hemoglobin test allows tailoring of colonoscopy
Weight gain in adulthood increases risk of colon cancer in men
Prostate irradiation raises long-term risk of colon cancer
August 2008
Plasma DNA more reliable than CEA for detecting recurrent esophageal cancer
Higher plasma folate associated with lower colorectal cancer mortality
July 2008
Vitamin D levels tied to colorectal cancer survival
Mucosa-restricted antigen induces immunologic response to colorectal cancer
June 2008
Avastin prolongs survival in colorectal cancer
Atorvastatin and celecoxib synergistic against colon cancer cells
Topoisomerase-1 may predict chemotherapy success in colorectal cancer
African Americans with family history of colorectal cancer often forgo screening
Genetic predisposition to colon cancer linked to better prognosis
May 2008
Highest colonoscopy screening rates are in low risk patients
Immediate diagnosis of colorectal lesions during colonoscopy possible
Adjunctive bevacizumab somewhat beneficial in metastatic colorectal cancer
Bowel tumor resection improves outcomes in unresectable liver metastases
Proton pump inhibitors don't appear to influence colorectal cancer risk
EGFR gene variants have gender-specific effects on colon cancer survival
April 2008
REFILE: Stop-and-go oxaliplatin effective in elderly colon cancer patients
Some cardiovascular risk seen with celecoxib used to prevent colon adenomas
Stop-and-go oxaliplatin effective in elderly colon cancer patients
CT colonography effective with limited bowel preparation
Abnormal Pap smears more likely in women with inflammatory bowel disease
New colorectal cancer susceptibility loci identified
FDG-PET detects recurrence of colorectal cancer early
March 2008
FOBT screening reduces emergency colorectal cancer admissions
Sulindac induces carcinogen-metabolizing enzymes in human colon cancer cells
Testing for colorectal cancer on the rise, but barriers to screening still exist
New colon screening recommendations offer choices
February 2008
KRAS mutations predict colorectal cancer response to cetuximab
Skin tumors common in hereditary nonpolyposis colorectal cancer
Aspirin associated with reduced colorectal cancer risk in men
EU approves Roche's Xeloda in colorectal cancer
January 2008
MicroRNA expression predicts colon cancer outcome
Chewing gum after cystectomy stimulates return of bowel motility
Narrow band imaging detects hereditary colorectal cancer
December 2007
Cryptosporidium parvum linked to colon adenocarcinoma
At-risk relatives of colorectal cancer patients not being screening
Colorectal cancer screening underused in Medicare population
Symptom prevalence low 4 years after successful colorectal cancer treatment
November 2007
Colorectal cancer survival differs by race and ethnicity
Rate of adenoma transition to colorectal cancer strongly age-dependent
CT colonography often detects extracolonic abnormalities in older patients
Number of lymph nodes examined does not influence colon cancer survival
Insulin levels point to colonic neoplasms in acromegaly
Osteopontin expression predicts colon cancer survival
October 2007
Endoscopists often recommend repeat colonoscopy too soon
Two-tier fecal occult blood screening offers effective colorectal cancer detection
Proton pump inhibitor use not linked to colorectal cancer
Obesity a significant risk factor for colorectal cancer: study
CT colonography has advantages for colorectal cancer screening
Broader US label for colorectal cancer drug Erbitux
September 2007
Capecitabine improves colon cancer survival
Targeted interventions increase colorectal cancer screening
Statins not linked to decreased colorectal cancer risk
Small bowel cancer screening may be warranted with Lynch syndrome
August 2007
Colorectal cancer screening rates low in Canada 3 years after guidelines issued
Statins do not lower colorectal cancer risk
MR colonography without bowel cleansing shows promise for screening
Vaccine works with chemotherapy in colorectal cancer
Laparoscopic-assisted surgery provides good long-term outcomes in colon cancer
July 2007
Plasma LPC may be early colorectal cancer marker
Stents for metastatic colon cancer improve survival, allow earlier chemotherapy
Counseling tied to improved survival after gastrointestinal cancer surgery
Fecal test, sigmoidoscopy effective for colorectal cancer screening
Variant on chromosome 8 tied to colorectal cancer
Capsule endoscopy identifies small bowel melanoma metastases
Body mass index associated with the risk of colon cancer
Repeated hepatectomy improves survival of recurrent metastatic colon cancer
Risk of colorectal cancer is increased in patients with juvenile polyposis
June 2007
Gastric cancer belongs to spectrum of hereditary colorectal cancer malignancies
Cetuximab a first line option for metastatic colorectal cancer
Perioperative chemotherapy curbs recurrence of colorectal cancer metastatic to liver
May 2007
Dietary fiber intake not tied to colorectal cancer risk
Monoclonal antibody active in chemorefractory metastatic colorectal cancer
Prognosis poor with high IL-6 before colorectal cancer surgery
Colon cancer a risk for uveal melanoma patients and their relatives
Certain IBD patients at greater colorectal cancer risk
Bevacizumab useful adjunct in metastatic colon cancer
April 2007
KRAS mutation linked with poor response to colorectal cancer treatment
Socioeconomics, treatment largely explain racial gap in colon cancer survival
CT colonography cost-effective for colorectal cancer screening
Post-polypectomy colonoscopy surveillance guidelines confirmed
REFILE: Superoxide produced by colonic bacteria may promote cancer
March 2007
Lymph node evaluation influences outcomes after colon cancer resection
Calcium, vitamin D protective for colorectal cancer
Fractalkine curbs metastatic colon cancer in mice
Follow-up colonoscopy is productive in colon cancer survivors
Superoxide produced by colonic bacteria may promote cancer
Single resection colorectal cancer and liver metastases offers benefits
Colorectal cancer salvage therapy better in younger patients
February 2007
Missed colorectal cancer rates higher with office-based colonoscopy
Synbiotic preparation reduces colon cancer risk factors
New fecal DNA test highly sensitive for colorectal cancer
High carb intake not linked to risk of colorectal cancer
Disparities in colon cancer screening seen in Medicare population
Vitamin D intake may cut risk of colorectal cancer
January 2007
Colonoscopy failure rates higher in the afternoon
Hormone replacement cuts colorectal cancer mortality
Colorectal cancer mortality in blacks unaffected by insurance status
Statin use does not cut risk of colorectal cancer
Medium-sized polyps seen on sigmoidoscopy may warrant follow-up colonoscopy
December 2006
Sedation-free colonoscopy tolerable and effective with upper endoscope
Chemotherapy delay after colon cancer surgery increases mortality
Medicare coverage of colonoscopy linked to earlier stage diagnoses
Slow colonoscope removal increases odds of spotting lesions
Residue-free NaP tablets effective, well-tolerated for bowel prep
CD55 mimic induces immune response in colorectal cancer patients
Meta-analysis confirms red meat consumption linked to colorectal cancer risk
November 2006
Tumor-specific colorectal cancer marker identified
S. bovis antigens could point to colon cancer
Colonoscopic cancer screening little used by VA hospitals
Subset of human colon cancer cells capable of initiating tumors
Reduction in IGF-1 inhibits colon tumorigenesis in mice
Benefit of colon cancer screening questioned for some older patients
Capsule endoscopy helpful in identifying, managing small bowel tumors
October 2006
Improved CT colonography an accurate screening tool for colorectal cancer
Updated ASCO guidelines highlight CEA tumor marker for colorectal cancer
Aldose reductase blockade curbs colon cancer in mice
Colonoscopy preferred by patients undergoing colon imaging
September 2006
FDA approves Amgen colon cancer drug Vectibix
Oral mucosal color suggests high risk of hereditary colorectal cancer
Low folate levels may decrease risk of colorectal cancer
New test predicts colorectal cancer outcomes
August 2006
Colonic neoplasms more prevalent among HIV-infected individuals
UK's NICE rejects two new bowel cancer drugs
Chronomodulation aids colorectal cancer therapy
Physical activity after colorectal cancer diagnosis may reduce mortality
EGFR mutations linked to gastrointestinal cancers
July 2006
Familial risks of colon and rectal cancer differ
A single negative colonoscopy may suffice for average-risk patients
Colony-stimulating factor recommended with aggressive chemotherapy
Ulcerative colitis worsens survival after colorectal cancer
Pseudopolyps predictive of colon cancer with ulcerative colitis
June 2006
Model may help identify hereditary colorectal cancer
May 2006
Colonoscopy of little benefit in very elderly patients
Stopping colon cancer chemotherapy early no better than no therapy at all
Colorectal cancer risk not increased overall in inflammatory bowel disease
April 2006
No long-term rise in colon cancer for ulcerative colitis patients
VEGF inhibition by short interfering RNA impairs colon cancer proliferation
Central adiposity linked to colon cancer risk in women
Detection of resectable recurrence of colorectal cancer is not improved with MRI
Coffee may not reduce colorectal cancer risk
Blacks with colorectal cancer less likely to get adjuvant chemotherapy
March 2006
Venous thromboembolism risk in colorectal cancer highest early after diagnosis
Calcium, dairy food associated with lower colorectal cancer risk
Electronic cleansing improves tolerability of CT colonography
Alcohol, tobacco, and male gender up risk of earlier onset colorectal cancer
Colonoscopy misses many small polyps
Hepatic arterial infusion improves survival in metastatic colorectal cancer
Trovax improves survival in metastatic colorectal cancer in phase II study
Tetracycline analogues induce apoptosis in colon cancer cells
IBD-related colon cancer carries similar prognosis as sporadic forms
Sentinal nodes do not predict metastatic colon cancer
Multiple genetic loci tied colorectal cancer susceptibility
February 2006
Long telomere length linked to poor prognosis in colorectal cancer
Fiber may benefit men more than women in terms of colon cancer protection
Oxaliplatin safely stopped with FOLFOX regimen for colorectal cancer
Physical activity does not cut colon cancer risk in women
Calcium plus vitamin D doesn't lower colorectal cancer risk in women
High magnesium intake lowers colon cancer risk in women
January 2006
MHC 1 levels tied to colorectal cancer prognosis
Fluorouracil combinations comparable in colon cancer outcome
Diabetes linked to colon cancer in ethnic Chinese population
Dietary acrylamide not linked to colorectal cancer in women
December 2005
Whole-body PET/CT efficiently stages colorectal cancer
Physical inactivity, central obesity worsen survival of colorectal cancer
Tumor-infiltrating immune cells may control early metastasis of colorectal cancer
Meta-analysis contradicts benefits of dietary fiber in protecting against colorectal cancer
Rise in chemotherapy for colon cancer coincides with improved survival
Matrilysin points to colorectal cancer metastatic potential
November 2005
First-line therapy for metastatic colorectal cancer cost-effective
High-fat dairy foods may reduce colorectal cancer risk
Low adiponectin levels may raise colorectal cancer risk in men
Meta-analysis confirms elevated colon cancer risk with diabetes
Colorectal cancer screening not necessarily right for elderly
Distal colon polyps don't increase proximal adenoma risk
Asbestos exposure may increase colorectal cancer risk in men
Calcium, phosphorus, dairy products protect against adenomas, colorectal cancer
CORRECTION: Study supports continued colorectal cancer screening of elderly patients
Diabetics at higher risk of colon cancer
Study supports continued colorectal cancer screening of elderly patients
October 2005
Blacks younger at age of colon cancer diagnosis
Virgin olive oil phenols inhibit colon carcinogenesis in vitro
Mutant DNA fragments detected in plasma of colorectal cancer patients
Half of eligible primary care patients not screened for colorectal cancer
Colonoscopy often inaccurate in localizing colorectal cancer
September 2005
NSAIDs protective against colon cancer in blacks and whites
Walking exercise improves bowel prep for colonoscopy
DNA repair gene methylation may precede colon cancer
Colorectal cancer screening underused in HIV patients
Immunochemical fecal tests worth considering for colorectal cancer screening
Troglitazone promotes colon cancer in mice
August 2005
Cholecystectomy modestly raises colon cancer risk
Inadequate sigmoidoscopy tied to colorectal cancer risk
Long-term aspirin and other NSAIDs lower colon cancer risk
Gene expression in colorectal cancer may help predict lymph node metastases
Methylated vimentin in fecal DNA: a potential colon cancer biomarker
July 2005
Echinacea not useful for common cold
Immunomodulators for inflammatory bowel disease raise lymphoma risk
5-ASA cuts colorectal cancer risk in ulcerative colitis patients
June 2005
Capecitabine effective alternative to fluorouracil/leucovorin for colon cancer
Colorectal cancer outcome in US varies by race and ethnicity
Laparoscopic surgery safe for radical resection of colon cancer
Claudin-1 may play a key role in colon tumors
Phase II trial shows Erbitux can prolong life in metastatic colorectal cancer
Automated test could aid colorectal cancer screening
European study confirms red meat link with bowel cancer
High vitamin B6 intake may reduce colon cancer risk in women
Avastin combination active against metastatic colorectal cancer
Fecal blood testing aids colorectal cancer screening
May 2005
Study published showing statins reduce risk of colorectal cancer
Genetic traits tied to pulmonary metastases from primary colorectal cancers
Oxaliplatin reduces risk of recurrence in early-stage colorectal cancer
Inflammatory bowel disease slightly increases hematopoietic cancer risk
Folic acid may help prevent colorectal cancer
April 2005
Gene defect differentiates familial colorectal cancer types
Low-dose statin combo blocks colon carcinogenesis in rats
APC expression in colonic mucosa may be early marker for polyps
Genetic test predicts colon cancer treatment response
Primary care measures boost colorectal cancer screening
Cell-cycle regulatory proteins linked with colorectal cancer prognosis
EU okays Roche drug for post-surgery colon cancer
March 2005
RF ablation curbs colorectal cancer liver metastasis
Screening for colorectal cancer recommended to begin 5 years earlier in blacks
Elevated C-reactive protein not tied to colorectal cancer risk in women
Men more likely to be screened for prostate cancer than colon cancer
February 2005
Mutant survivin gene delivery inhibits colon cancer in mice
Colorectal cancer survival lower in Europe than in US
Lymph node evaluation often substandard in colorectal cancer
January 2005
Single in-office FOBT unreliable screen for colon cancer
Connective tissue growth factor inhibits metastasis in colorectal cancer
Red meat consumption linked to colorectal cancer
December 2004
Fecal DNA test promising for colorectal cancer detection
Colorectal cancer screening underused
Colorectal cancer screening failing to reach 41.8 million Americans at average risk
Colonoscopy still best for detecting colon cancer
PET/CT improves detection of metastatic colorectal cancer
Diagnostic certainty on virtual colonoscopy predicts polyp risk
November 2004
Genentech colon cancer drug effective in combination regimen
TGF-beta suppresses colon cancer progression
MYH gene mutation tied to colorectal cancer
New CD guides management of liver metastases from colorectal cancer
Less intense therapy yields comparable survival for some colorectal cancer patients
CT colonography likely to decrease demand for traditional colonoscopy
Obese women have a fourfold higher risk of colon cancer
October 2004
UK to launch bowel cancer screening
California gets high marks for colorectal cancer screening
Galectin-3 ligand could be colon cancer marker
Chronic insulin therapy may increase risk of colorectal cancer
September 2004
Retinoic acid may prevent colon adenoma formation
Colonoscopy may miss more adenomas than previously thought
Urinary, bowel, sexual problems persist long after localized prostate cancer therapy
Colon cancer colonoscopy has relatively low miss rate
Fecal calprotectin test not recommended for colorectal cancer screening
Fecal COX-2 mRNA assay may spot colorectal cancer
Colonoscopic resection safe and effective for lateral spreading tumors
August 2004
Glucagon-like peptide boosts colon cancer in mice
Survival benefit of adjuvant chemotherapy for colon cancer limited
July 2004
CT identifies large polyps during colorectal cancer screening
Swedes develop assays for disseminated colorectal cancer tumor cells
Colon cancer risk of colorectal cancer mutation greater in men
Higher intake of milk and calcium tied to lower risk of colorectal cancer
June 2004
Fecal occult blood screening cuts colorectal cancer mortality
Oncolytic virus homes in on colon cancer cells
Statins tied to reduced colorectal cancer risk
New chemotherapy regimens improve colon cancer outcomes
May 2004
Direct mailing of fetal occult blood tests ups colorectal cancer screening rates
Chemotherapy delivery route does not affect colon cancer survival
Routine CT scans and CEA useful in follow-up of colorectal cancer
April 2004
Loss of imprinting of IGF2 gene a hereditary risk factor for colon cancer
Alcohol consumption may increase colorectal cancer risk
Fecal DNA testing shows promise in detecting colon cancer
CT colonography sensitivity low
Elevated plasma C-peptide levels linked with colorectal cancer risk in men
March 2004
GABA-receptor agonist suppresses colon cancer growth and metastasis
Prostate cancer therapy not tied to colorectal cancer risk
Leptin may provide a link between obesity and colon cancer
Multiple factors impede colorectal cancer screening
CT colonography helpful in cancer screening
Fluoropyrimidines helpful after colon cancer surgery
February 2004
Genentech wins US FDA OK for colon cancer drug
Guidelines revised for hereditary nonpolyposis colorectal cancer testing
Intraperitoneal hyperthermic chemotherapy shows promise for colorectal cancer
Founder mismatch repair mutation common in hereditary colorectal cancer
Dietary glycemic load directly linked to colon cancer risk in women
CRP elevation predictive of colon cancer
African Americans less likely to undergo colorectal cancer screening
January 2004
Beer intake helps prevent colon cancer in rats
5-ASA therapy for inflammatory bowel disease no bar to colon cancer
Cause of most colorectal cancers remains elusive
BRCA mutations not linked to colon cancer risk
Costs lower if colorectal cancer detected by screening rather than by symptoms
December 2003
High energy intake may be tied to colon cancer risk
Risk factors for colonic neoplasia identified in asymptomatic cohort
Cigarette smoking strongly tied to death from colorectal cancer
November 2003
Nitrate in water tied to colon cancer risk in some
Four-drug regimen feasible in colorectal cancer
Aspirin suppresses aberrant crypt foci in colon cancer patients
October 2003
Urologic malignancy raises the risk of colorectal cancer
Family history of colorectal cancer associated with increased risk
FDA to review ImClone colorectal cancer drug
September 2003
Virtual colonoscopy still not ready for widespread use
Peroxisome proliferator activated receptor (PPAR) may play role in colon cancer
August 2003
Vaccine may extend colon cancer survival
Magnification endoscopy may improve assessment of colon cancer risk
Study affirms safety of oxaliplatin in advanced colorectal cancer
July 2003
Non-infusional regimen may be suitable first-line therapy for colorectal cancer
Clusterin a potential biomarker of colon cancer
Obesity raises mortality risk in women with colon cancer
Microsatellite-instability status predicts benefit of adjuvant chemotherapy for colon cancer
Oxaliplatin with fluorouracil-leucovorin effective for progressive colon cancer
UK population study confirms benefits of colorectal cancer screening
June 2003
Methylation-specific PCR may pick up recurrent colorectal cancer in serum
High intake of carbohydrates does not increase colorectal cancer risk
Vitamin D2 analog active against leukemia, myeloma, and colon cancer
COX-2 inhibitor use not cost-effective in preventing colon cancer
Night-shift work tied to increased risk of colorectal cancer in women
Anti-angiogenic agent improves survival in metastatic colorectal cancer
May 2003
Anti-angiogenetic drug plus chemo prolongs colorectal cancer survival
SMAD7 points to negative outcome in colorectal cancer
Growth factor receptor-related protein inhibits colon cancer growth in mice
High calorie diet linked to improved survival in colon cancer patients
Colonoscopy more cost-effective than colorectal cancer chemoprophylaxis
Gene family analysis reveals possible new therapeutic targets for colon cancer
Latest dietary fiber data support protective effect against colon cancer
April 2003
Combination chemotherapy effective against advanced colorectal cancer
Integrin antagonist combined with 5-FU improves colorectal cancer outcomes
Acetylcholinesterase found in colon carcinoma, may present therapeutic target
Excess body weight a significant risk factor for colorectal cancer in older women
Novel combination may be useful against colon cancer
March 2003
Screening for colorectal cancer lags behind prostate cancer testing in US
Epigenetic IGF2 abnormality predicts colorectal cancer risk
Deguelin inhibits colon carcinogenesis in mice
February 2003
Colon polyp recurrence high after screening and treatment
Bacterial enterotoxin may protect against colon cancer
Britain plans colorectal cancer screening programme
New colorectal cancer screening guidelines issued
January 2003
Caloric restriction early in life may reduce later risk of colon cancer
Mutations in hemochromatosis gene linked to increased risk of colon cancer
December 2002
Medicare coverage has not increased colorectal cancer screening rates
Bevacizumab plus chemotherapy promising colorectal cancer therapy
Risk factors for VRE bloodstream infection in colonized cancer patients identified
Single sigmoidoscopy may provide effective colorectal cancer screening
JC virus oncoproteins found in malignant epithelial colon tumors
November 2002
Model suggests genetic instability mutation initiates colon cancer
Dietary habits influence colorectal cancer risk in Asian population
Ranitidine may improve survival in some cases of colon cancer
Video capsule endoscopy deemed superior to small bowel radiography
October 2002
Oxaliplatin delays progression in metastatic colorectal cancer
Average-risk women should begin colorectal cancer screening at age 50
Unique nuclear matrix proteins associated with colon cancer metastases to liver
September 2002
Multiple VEGF polymorphisms identified in colorectal cancer cells
Simultaneous resection of colon cancer and liver metastases can be done safely
August 2002
New CT colonography method shows promise in detecting colonic lesions
COX-2 inhibitor prevents liver metastasis of colon cancer in mice
With similar treatment, blacks and whites with colon cancer fare equally well
Src upregulation disrupts cellular contacts, which may permit colon cancer spread
Obesity linked to increased colorectal cancer risk in premenopausal women
July 2002
Low-dose CT colonography accurately detects large colorectal neoplasms
Large or multiple adenomas at first colonoscopy linked with recurrence
Colorectal cancer screening urged for all men and women beginning at 50
Excessive IGF-I may explain link between diet, colon cancer
US Senate committee approves colorectal cancer screening bill
June 2002
Laparoscopy may provide long-term survival benefit to colon cancer patients
Routine colon cancer screening should start at age 50 for most people
May 2002
Immunocytochemical stool test detects colon cancer
Colonoscopy every 3 years recommended for patients at high risk for colon cancer
Vitamin D protects against colon cancer by inducing bile acid breakdown
Prognosis of stage B colon cancer improves with higher lymph node recovery
Five-year screening intervals for colorectal cancer appropriate for some
Raltitrexed more toxic than other regimens for colorectal cancer
April 2002
Colorectal cancer mortality remains high among poor US blacks
Enzyme level may predict benefit of chemotherapy for colorectal cancer
Risk of other primary cancers increased in colorectal cancer patients
Green tea shows protective effect against gastrointestinal cancer
March 2002
Polymorphism of growth hormone gene linked to reduced colorectal cancer risk
Moderate daily calcium intake seems to reduce risk of colon cancer
UK's NICE rejects routine use of three bowel cancer drugs
February 2002
All colorectal cancer screening methods effective; best still uncertain
Folate linked to reduced colorectal cancer risk in women
High incidence of second primary colorectal cancer reported
January 2002
APC stool test may allow early detection of colorectal cancer
Daily aspirin not cost-effective for preventing colorectal cancer
Colonoscopy can be cost-effective for evaluating young patients with rectal bleeding
Reduction of 17HSD enzyme may explain influence of estrogen in colon cancer
Colonoscopy appears to be the best strategy for colorectal cancer screening
Benefits of continued colorectal cancer screening persist beyond 10 years
Alcoholism increases risk of high-risk adenomas and colon cancer
Diet seems to have no clear link to colorectal cancer risk
December 2001
Epidermal growth factor blocking antibody to be tested in colorectal cancer
Computer model suggests stem cell overproduction leads to colon cancer
November 2001
Oxaliplatin and irinotecan helpful in 5-FU-resistant colorectal cancer
October 2001
Novel antitumor drugs inhibit colon cancer cells
"Virtual colonoscopy" brings comfort to colon cancer surveillance
Microsatellite instability screening in colorectal cancer is useful and cost-effective
Recently approved colorectal cancer regimen increases risk of early death
Gene linked to colorectal cancer metastasis presents therapeutic target
September 2001
Duo of monoclonal antibodies fights murine colon cancer better than one alone
Benign lesions may give rise to colorectal cancers with microsatellite instability
August 2001
Chronic alcohol consumption increases risk of colon cancer gene mutation
Fecal occult-blood test and sigmoidoscopy miss many colorectal cancers
Chronic alcohol use increases risk of microsatellite instability in colon tumors
July 2001
CD155 gene is overexpressed in colorectal cancer
Cyclin D1 polymorphism tied to increased risk of colon cancer at young age
Combination approach may offer novel treatment for colorectal cancer
Companies win NICE appeal on colorectal cancer drugs
May 2001
Cancer vaccine shows promise against colorectal cancer
Monoclonal antibody offers promising therapy for refractory colorectal cancer
FDA approves Roche's Xeloda for metastatic colorectal cancer
April 2001
Drug rationing seen as harming bowel cancer treatment in UK
Chemotherapy for colon cancer underused in elderly, misused in women
Risk factors for recurrence of advanced colonic adenomas identified
Molecular markers predict survival after chemotherapy for colon cancer
Oral contraceptives reduce colorectal cancer risk
Trials of rofecoxib to prevent colonic polyps begin
March 2001
Melanoma, cancer of testis, colon linked to work-related radiation exposure
February 2001
New colorectal cancer screen wins FDA premarket clearance
ImClone colorectal cancer drug put on fast track by FDA
January 2001
Common cause of inflammatory bowel disease and colorectal cancer unlikely
November 2000
Microsatellite instability status predicts colorectal cancer outcome
October 2000
Stool assay for altered DNA may revolutionize screening for colorectal cancers
Oxford BioMedica's colorectal cancer vaccine trial receives ethical approval
Colonoscopy best method for colorectal cancer screening
Chronic elevation of insulin and IGF levels may raise colorectal cancer risk
September 2000
Irinotecan improves outcome of metastatic colorectal cancer
Hereditary nonpolyposis colon cancer common in rectum, rectosigmoid
Olive oil has protective effect on colorectal cancer development
Cancer-specific survival after colorectal cancer surgery does not vary by age
5-year sigmoidoscopy most cost-effective in screening for colon cancer
Meta-analysis suggests OncoVAX is effective against colon cancer
August 2000
Children of mothers with colorectal cancer have increased cancer risk
Catalytic subunit of lipid kinase suppresses colorectal cancers in mice
Folate deficiency promotes p53 strand breaks in rat colon
Oral fluorouracil plus eniluracil efficacious in treating metastatic colon cancer
July 2000
Colonoscopy favored for colorectal cancer screening in asymptomatic adults
Small-bowel lymphoma associated with unrecognized celiac disease
Anti-CEA imaging useful complementary follow-up to mammography
June 2000
Myriad raises $24 million to help speed colon cancer drug development
Consumption of nonfiber carbohydrate increases risk of colorectal cancer
Loss of expression of androgen-receptor isoform detected in colon cancer
Many primary physicians' colorectal cancer screening practices inadequate
Limited counseling usually suffices after genetic test for hereditary colon cancer
Colonoscopy superior to barium enema for postpolypectomy surveillance
Laxative use not associated with increased colorectal cancer risk in women
Xenova stock falls as company halts colorectal cancer study
May 2000
Colorectal cancer mortality higher among blacks and the uninsured
Colony-stimulating factor use in clinical practice varies widely from ASCO guidelines
Age alone should not rule out chemotherapy after colon cancer surgery
Quality of care study of breast cancer and colon cancer patients gets under way
Colorectal cancer survival influenced by sex, tumor location, and phenotype
Colon cancer recurrence may be reduced with intraperitoneal 5-fluorouracil
April 2000
FDA approves Camptosar for first-line treatment of advanced colorectal cancer
Endoscopic colorectal cancer screening pays for itself
Endoluminal colonic wall stents effective in management of large bowel obstructions
Acetaminophen may protect against colon carcinogens
March 2000
Irinotecan improves survival in metastatic colorectal cancer
Tegafur might suppress angiogenesis in patients with colorectal cancer
FDA oncology advisers reject approval of new colorectal cancer therapy
February 2000
Lutein the most potent carotenoid for colon cancer prevention
January 2000
Tissue factor expression predicts metastasis and prognosis in colorectal cancer
Microsatellite instability in colorectal cancer linked to more favorable outcome
Association between meningioma and colorectal cancer detected
Doppler technique identifies colorectal cancer patients at risk of recurrence
Intake of olive oil and fish oil reduces colon cancer risk in rats
December 1999
Colorectal cancer screening seems not to reduce mortality in community setting
Genomic instability causally linked to colorectal cancer
Guanylyl cyclase C mRNA expression signals metastasis of colorectal cancer
November 1999
Racial colon-cancer survival gap is smaller in clinical trials
Estrogen replacement reduces risk of colorectal cancer in postmenopausal women
October 1999
COX-2 levels higher in rectal tumors than in tumors in other locations in the colon
Medicare funding increases colorectal cancer screening and detection
Lifestyle patterns are important predictors of colon cancer risk
Cathepsins, plasminogen activators linked to progression, aggressiveness of colorectal cancer
COX-2 levels correlate with reduced survival in colorectal cancer patients
Small-bowel toxicity in colorectal cancer patients linked to 5-FU-based therapy
September 1999
Early feeding after colon resection is safe and reduces hospital stay
August 1999
Protein marker nm23 offers prognostic information in colorectal cancer patients
Liver metastases from colorectal cancer potentially curable with surgery
Laparoscopic approach to colorectal cancer compares well with open management
Obesity linked to colon cancer risk in men and women
8p allelic imbalance linked to poor prognosis in stage C colorectal cancer
Serum vitamin D levels decrease with progression of colorectal cancer
Women with ovarian, endometrial cancers at increased risk of colorectal cancer
July 1999
Genetic predisposition to colorectal cancer seen among young Hong Kong residents
Genetic testing useful in subset of hereditary colorectal cancer families
Thymosin alpha 1 increases survival in rat model of metastatic colon cancer
June 1999
Kinase-targeted compound inhibits colonic tumor growth in murine study
Mismatch repair mutations identified in African Americans with colorectal cancer
Serum IL-6 level linked to tumor proliferative activity in colorectal cancer patients
Association of K-ras mutations with p16 methylation in human colon cancer reported
May 1999
Provider caseload not related to patient survival after colorectal cancer
Adjuvant chemotherapy recommended for all Dukes' B colon cancer patients
p53, K-ras mutations not prognostic in patients with colorectal cancer
Low intake of animal products may be linked to low colon cancer rate among black South Africans
Beta-catenin targets cyclin D1 gene in human colon cancer cells
Follow-up of distal colonic tubular adenoma should not be based on adenoma size
April 1999
Simple bowel prep adequate for flexible sigmoidoscopy
Large increase in incidence of proximal colorectal cancer among black Americans reported
Dietary lectin in broad beans may slow colon cancer progression
Expert hails new ASCO postsurgery colorectal cancer surveillance guidelines
Lovastatin boosts ability of NSAIDs to ward off colorectal cancer
Dietary fiber intake inversely associated with colorectal cancer mortality
ASCO recommends fewer colonoscopies following colorectal cancer surgery
March 1999
Type 2 diabetes a risk factor for colorectal cancer in women
Angiogenesis inhibitor begins phase II testing in colon cancer
Oral contraceptive use not linked to colorectal cancer risk
Dietary nitrosamines linked to colorectal cancer
UK colorectal cancer and chlamydia pilot screening projects launched
Regular stool screening lowers colon cancer risk by one-third
February 1999
Colon cancer metastasis to liver reduced by inhibition of MUC2 mucin synthesis
Irinotecan's efficacy confirmed in previously treated metastatic colorectal cancer
Colorectal cancer screening rates low in patients over 50 years old
Cholecystectomy "weakly" increases risk of proximal colon cancer
January 1999
Cancer vaccine prevents post-op recurrence in subset of colon cancer patients
Nonaspirin NSAIDs cut colorectal cancer risk in half with long-term use
Conformal radiation of prostate reduces risk of bowel side effects
Fiber intake not related to colorectal cancer risk in women
Spectrofluoroscopy showing promise in diagnosis of colon cancer