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Types of Cancer > Gynecologic Cancers > Ovarian Cancer > News

OncoLink Cancer Resources and Reuters News


July 2009

Ovary removal may raise risk of lung cancer

Early menarche predicts decreased survival with ovarian cancer

Ultrasound superior to symptoms for predicting ovarian cancer

Hormone therapy linked to ovarian cancer

No pulmonary morbidity after diaphragm surgery for ovarian cancer


June 2009

Serum biomarker panel identifies early-stage ovarian cancer

Ovarian tissue transplant may restore fertility after cancer treatment

No benefit to treating ovarian cancer relapse based on rising CA125 alone


May 2009

Topotecan-docetaxel combo beneficial in heavily treated gynecologic cancer patients


April 2009

SNPs sharpen absolute risk estimates for prostate cancer

Synchronous ovarian and endometrial cancers linked with better outcomes

CRM197 enhances antitumor effect of paclitaxel in ovarian cancer


March 2009

Ovarian cancer screening fails to identify early disease

Glucose levels predict outcomes in ovarian carcinoma

CA125 and ultrasound effective for ovarian cancer screening

Additional chemo agent no benefit in advanced-stage ovarian cancer

Intraoperative chemotherapy in peritoneal cavity promising for ovarian cancer


February 2009

Annual screening for ovarian cancer in BRCA1/2 carriers deemed ineffective

Ovarian preservation appears safe in young endometrial cancer patients


December 2008

Oregovomab not effective for maintenance therapy in ovarian cancer

Silencing MYC oncogene has therapeutic potential in ovarian cancer

Plasma endoglin not useful marker in ovarian cancer


October 2008

U.S. says LabCorp ovarian cancer test sales illegal


September 2008

Trabectedin shows promise in recurrent ovarian cancer


August 2008

Symptom index plus CA 125 improves ovarian cancer detection


July 2008

Obesity increases risk of certain ovarian cancers

Risk of breast, ovarian cancer increased in infertile women

Topotecan combination no extra help in ovarian cancer

Risk of ovarian cancer is not reduced with analgesic use


June 2008

Ovarian stimulation with letrozole does not raise breast cancer recurrence risk

Aggressive care does not improve survival in late ovarian cancer


May 2008

Reproductive factors more tightly linked to premenopausal ovarian cancer


April 2008

Simultaneous operations feasible for hereditary breast-ovarian cancer syndrome

Ovarian serous carcinoma may originate in the fallopian tube

Mifepristone may improve cisplatin efficacy in ovarian cancer


March 2008

Ovarian cancer best treated at specialized hospitals in the Netherlands


February 2008

Thalidomide for recurrent ovarian cancer improves response

GnRH agonist reduces chemotherapy-induced ovarian failure

Blood test provides early detection of ovarian cancer

Androgens not associated with risk of ovarian cancer


January 2008

Caffeine linked to reduced incidence of ovarian cancer

Ultrasound quality strongly affects ovarian cancer management

Bevacizumab combination promising against ovarian cancer

Chronic inflammation not seen important in development of ovarian cancer

BRCA mutations tied to improved survival in Ashkenazi ovarian cancer patients


December 2007

Transvaginal ultrasound screening fails to detect early-stage ovarian cancer


November 2007

Paclitaxel-ceramide nanoparticulate overcomes drug resistance in ovarian cancer

Protective effect of OC use against ovarian cancer wanes after discontinuation


October 2007

Guidelines fail to identify most early stage ovarian cancers


September 2007

Age and other factors predict stage III ovarian cancer prognosis


July 2007

Survivors of ovarian germ cell tumors may retain fertility after surgery and chemo

Inhibin a potential marker of ovarian cancer in postmenopausal women

Ovarian cancer vaccine reinforces patient's immune response to tumor


June 2007

Lower limb lymphedema common in survivors of gynecological cancer

Anti-estrogen therapy promising in some ovarian cancers

Polycystic ovary syndrome appears to increase uterine leiomyomata risk

VEGF-Trap active in recurrent refractory advanced ovarian cancer


May 2007

Transvaginal sonographic screening may catch ovarian cancer early

Oophorectomy cuts breast, ovarian cancer risk for those with BRCA1/2 mutations

Symptoms common before ovarian cancer diagnosis in older women


April 2007

Ovarian cancer often under treated: study

Infertility drugs safe after borderline ovarian tumor treatment


March 2007

Supracervical hysterectomy alternative for ovarian cancer

Tumor vascular proteins may be biomarkers for ovarian cancer

Low-dose combination oral contraceptives protect against ovarian cancer


February 2007

Pain management at end of life seen inadequate in women with ovarian cancer

Pregnancy and oral contraceptives offer strongest anti-ovarian cancer effects

Absolute risk of second cancer small after hairy cell leukemia


January 2007

Lymphadenectomy improves survival in early ovarian cancer

First-line gemcitabine/carboplatin promising for advanced ovarian cancer


December 2006

Cisplatin and epirubicin combat germ cell tumors

Symptom screening may detect ovarian cancer earlier


November 2006

Ovarian ablation and chemotherapy comparable in breast cancer

Cell signaling protein correlates with ovarian cancer survival

CORRECTION: RF ablation may be useful in ovarian cancer metastatic to the liver

Polycystic-size ovaries common in healthy adolescents

LPAAT-beta an emerging prognostic, diagnostic, therapeutic target in ovarian cancer


October 2006

Benign ovarian cysts linked to lower breast cancer risk

Hormone therapy linked to ovarian cancer risk

Fanconi anemia gene suppression linked to familial ovarian cancer


September 2006

Poor ovarian cancer survival in black women not due to treatment differences

Family breast cancer history boosts ovarian cancer risk


August 2006

Obesity may make ovarian cancer more aggressive

Targeting focal adhesion kinase may lead to new ovarian cancer therapy

Optimistic ovarian cancer patients less distressed

Genetic evidence supports endometriosis as ovarian cancer precursor


July 2006

US OKs Lilly drug for ovarian cancer, spurns panel

Regular paracetamol/acetaminophen use may cut ovarian cancer risk


May 2006

Ovarian failure relatively rare after childhood cancer

IL-18 and FGF-2 complement CA125 in detecting ovarian cancer


April 2006

Pre-maintenance CA-125 level predicts risk of ovarian cancer relapse

Sedentary women may have increased ovarian cancer risk

Src inhibition a promising therapeutic approach to ovarian cancer


March 2006

Gemzar no help for ovarian cancer: US FDA staff


February 2006

Surgery by gynecologic oncologist improves ovarian cancer survival

Aspirin derivative active against cisplatin-resistant ovarian cancer cells

High levels of dairy foods may increase ovarian cancer risk


January 2006

Gynecologic oncologists have better outcomes than surgeons treating ovarian cancer

Surgery reduces gynecologic cancer risk in Lynch syndrome patients

Analgesic drug use may cut risk of ovarian cancer

Aggressive surgery improves survival in advanced ovarian cancer

BRCA1, BRCA2 mutations underestimated in ovarian cancer


December 2005

Ovaries safely retained after treatment of low-grade endometrial stromal sarcoma


November 2005

Glucose-sensitive PET points to ovarian cancer response

Physical activity may protect against ovarian cancer


October 2005

EGFR blocker and photodynamics combat ovarian cancer

Earlier diagnosis of ovarian cancer possible with pelvic imaging/CA125

Preoperative CA-125 level predicts outcome in stage I ovarian cancer

Ovarian malignancy commonly coexists with endometrial cancer in young women


September 2005

Family history common in women with breast or ovarian carcinoma

Genentech halts Avastin ovarian cancer trial

Familial ovarian cancer screening approach may be flawed

Repressor splicing factor gene stimulates ovarian cancer


August 2005

LHRH peptide targets chemotherapy to ovarian cancer cells

Abdominal swelling and pain commonly precede ovarian cancer diagnosis

High intake of milk, lactose may raise ovarian cancer risk


July 2005

Absorbable sling enhances early continence after radical prostatectomy

High IL-6 levels tied to low hemoglobin in ovarian cancer

ZAC gene silencing tied to ovarian cancer progression


June 2005

Short-term oral contraceptive use decreases ovarian cancer risk

Echovirus type 1 effective in ovarian cancer model

Psychosocial support linked to lower IL-6 levels with ovarian cancer


May 2005

Anti-MUC1 antibodies may protect against ovarian cancer

MRI technique helps track ovarian cancer therapy

Moderate activity may reduce ovarian cancer risk

Serum protein panel accurately detects early ovarian cancer


April 2005

Lymphadenectomy in ovarian cancer does not prolong survival

Genistein may help overcome cisplatin-resistance in ovarian cancer

Routine appendectomy indicated during surgical staging of ovarian cancer


February 2005

Conservative surgery for ovarian tumors spares fertility

Increased clusterin in ovarian cancer linked to tumor aggression


January 2005

"Kissing ovaries" a sign of severe endometriosis

Histone deacetylase inhibitors active against ovarian cancer cells

Progesterone receptor gene mutants associated with ovarian cancer


December 2004

Gene expression profile accurately predicts ovarian cancer outcome

Additional surgical debulking no help in ovarian cancer survival

NICE issues preliminary recommendations on ovarian cancer drugs


November 2004

Ovarian cancer risk increases with cumulative oral estrogen intake

Heterotopic ovary transplant maintains hormonal function


October 2004

New model better predicts genetic risk of breast and ovarian cancer

Ovarian radioablation aids breast cancer therapy


September 2004

Teenage girls urged to visit gynecologist before Pap testing begins

Chemotherapy improves survival of stage I ovarian cancer

Transplant of cryopreserved ovarian tissue leads to live birth

Oncogene hypermethylation in serum DNA indicates early-stage ovarian cancer

CA-125 blood test best for predicting outcome of ovarian cancer

Glycoprotein detects early-stage ovarian cancer

IVF may be safe after treatment for borderline ovarian tumor


August 2004

Molecular markers help detect early ovarian cancer

T cell subset fosters ovarian tumor growth

Endometriosis, primary infertility tied to increase risk for ovarian cancer

Increased diesel exhaust exposure increases risk of ovarian cancer


July 2004

Delaying pregnancy lowers risk of ovarian cancer

Lysophosphatidic acid may point to early ovarian cancer


June 2004

First woman pregnant after ovarian transplant

Fertility drugs not tied to greatly increased risk of ovarian cancer

Study finds that symptoms precede diagnosis of ovarian cancer

Preventive Services Task Force recommends against routine ovarian cancer screening

Ovarian cancer surgery in Maryland often performed by inexperienced surgeons


May 2004

Loss of gene promotes human ovarian carcinoma

Blood test shows promise in ovarian cancer


April 2004

Frequent, vigorous activity may up the risk of ovarian cancer in older women

Childhood tumors not increased after maternal ovarian stimulation


March 2004

Human kallikrein 8 predicts a favorable outcome in ovarian cancer

High dietary folate intake linked to decreased risk of ovarian cancer


January 2004

Response to 9-AC as second-line treatment of ovarian cancer modest

Thrombocytosis linked to disease progression in advanced ovarian cancer

"Absolute survival benefit" best conveys risk and benefits of chemotherapy


December 2003

Predictors of occult metastasis of germ cell tumor identified


November 2003

Overexpressed protein may disrupt BRCA2 in sporadic breast, ovarian cancers


September 2003

Surgery at teaching hospital may improve survival for advanced ovarian cancer

Rare ovarian tumor reported in teen with transgenerational DES exposure


August 2003

Height and BMI in adolescence tied to ovarian cancer risk


July 2003

CA 125-targeted immunotherapy may prolong survival in ovarian cancer

Gynecologic surgery may protect BRCA carriers against ovarian cancer

Ovarian and adrenal venous catheterization and sampling should be limited

New marker could improve diagnosis of ovarian cancer


June 2003

Human kallikrein 8 identified as an ovarian cancer marker

Zeltia's Yondelis shows promise in ovarian cancer

Paclitaxel plus platinum improves survival in relapsed ovarian cancer


May 2003

Endometrial and ovarian cancer often associated

Lysophosphatidic acid uses cyclin D1 to stimulate ovarian cancer growth

Return of ovarian function after osteosarcoma chemotherapy common

Better survival noted in ovarian cancer patients with BRCA mutations


April 2003

Combined IP/IV chemotherapy ups survival in advanced ovarian cancer

Ovarian cancer cells overexpress collagen to resist chemotherapeutic drugs

Phenoxodiol induces apoptosis in chemoresistant ovarian cancer cells

Demethylation of ovarian cancer gene leads to cisplatin resistance


March 2003

Murine model of epithelial ovarian cancer developed

Mutations in low-grade serous ovarian cancer suggest target for therapy

Incessant ovulation may increase risk of ovarian cancer


February 2003

Fertility preserved in most women with malignant germ cell ovarian tumors

BRCA2 N372H polymorphism linked to small increased risk of ovarian cancer


January 2003

UK updates advice for using Taxol in ovarian cancer

Gemcitabine-cisplatin regimen successful for relapsed ovarian cancer

Ovarian cancer survival markedly better when tumors show T cell infiltration

Post-op chemotherapy improves outcomes of early ovarian cancer

Bristol-Myers' Taxol set to lose first choice rating in UK for ovarian cancer

Ovarian stimulation with tamoxifen may preserve fertility in breast cancer patients


December 2002

Potential early biomarkers of ovarian cancer identified

After stopping oral contraceptives, protection against ovarian cancer persists


November 2002

Dose-dense cisplatin plus paclitaxel effective in advanced ovarian cancer

Refractory ovarian cancer responds to microtubule inhibitor in phase II trial

Anti-cancer compound sensitizes ovarian tumors to cisplatin


October 2002

Chemotherapy targeted to endometrial, ovarian cancers more effective, less toxic

Elevated IGF-1 linked to risk of ovarian cancer in younger women

CXCR4 receptor antagonist inhibits ovarian cancer stimulation by chemokine

Apoptotic agent yields favourable results in ovarian cancer


September 2002

Calcium intake may lower ovarian cancer risk


August 2002

Ovarian cancer risk in young breast cancer patients increased with family history

Secondary surgery predicts survival in recurrent micropapillary serous ovarian cancer

HRT use added to risk factors for epithelial ovarian cancer

Carboplatin monotherapy may be option for first-line ovarian cancer therapy

Excess weight in adolescence linked to ovarian cancer


July 2002

Calcium intake from dairy products linked to reduced ovarian cancer risk

Long-term estrogen replacement therapy linked to increased ovarian cancer risk


May 2002

Conservative surgery safely preserves fertility in some cases of ovarian cancer

CT scan scoring model predicts resectability in ovarian cancer

Experimental test shows promise for detecting ovarian, endometrial cancers


April 2002

Successful intersibling whole ovary transplantation reported from China

New biomarkers for ovarian, breast, and head and neck cancers identified

Gynecologic abnormalities common among women with rectal cancer

HRT may pose modest increase in ovarian cancer risk in postmenopausal women


March 2002

Paclitaxel continuation extends disease-free survival in advanced ovarian cancer

Danazol use for endometriosis linked to ovarian cancer risk

African-American ovarian cancer patients at increased risk for death


February 2002

Defined genetic changes create murine model of ovarian cancer

Ovarian hyperstimulation for IVF does not increase cancer risk

BRCA mutations tied to improved survival in ovarian cancer patients

NICE recommends Schering-Plough's Caelyx for advanced ovarian cancer

Serum protein profiling may allow early detection of ovarian cancer


January 2002

Cisplatin, etoposide "highly effective" in ovarian cancer studies

Infertility drug use not linked to ovarian cancer risk

Loss of heterozygosity in BRCA1 gene predicts mutation status of ovarian tumors

Progestin largely responsible for OC's anti-ovarian cancer effect


December 2001

LMW heparin or compression both prevent thromboembolism after gynecologic surgery

Conservative surgery for borderline ovarian tumors safe, preserves fertility


November 2001

Rise in UK ovarian cancer cases prompts call for action

CA-125 doubling predicts ovarian cancer progression when levels remain high

Antioxidants do not protect against ovarian cancer


October 2001

MGI Pharma to expand enrollment in phase II ovarian cancer trial

Diet rich in carotenoids may reduce ovarian cancer risk


September 2001

Ovarian autotransplantation may preserve fertility in cancer patients

Biomarkers could aid in evaluation of new ovarian cancer therapies

Red meat consumption associated with increased risk of ovarian cancer


August 2001

Ovulation induction safe following conservative treatment of borderline ovarian tumor

Symptoms associated with ovarian cancer may allow earlier diagnosis


July 2001

OCs do not reduce ovarian cancer risk in women with BRCA mutations

Pegylated doxorubicin comparable to topotecan for recurrent ovarian cancer

Hyperthermia overcomes platinum resistance in ovarian cancer

Minilaparotomy is a feasible approach for colon cancer resection


May 2001

Tubal ligation linked to reduced risk of ovarian cancer in high-risk women

Nitrates in water linked to increased bladder and ovarian cancer risk in older women

Suppression of IL-6 might improve chemotherapy for ovarian cancer patients


March 2001

Temporary ovarian suppression may prevent chemotherapy-induced infertility

Progestin may protect against ovarian cancer through TGF-beta mediation


January 2001

Alza's Caelyx approved in Canada for refractory ovarian cancer

Degree of differentiation predicts survival in invasive epithelial ovarian cancer


November 2000

Promising new compound protects ovaries against chemotherapy, radiation


September 2000

P53 gene therapy shows promise in ovarian cancer

Ovarian cancer prognosis better in women with history of breast cancer

Induction of apoptosis may explain protective effect of OCs against ovarian cancer

Fused ovarian cancer and dendritic cells stimulate T-cell response against tumor

Dendritic cells pulsed with ovarian cancer peptides stimulate specific CTL response


August 2000

Transvaginal ultrasonography screening detects early-stage ovarian cancer


July 2000

Levels of soluble Fas elevated in women with ovarian cancer

Low-dose oral contraceptives effective in reducing ovarian cancer risk

Conservative surgery for malignant ovarian germ cell tumors preserves fertility

Undetectable genetic mutations appear to increase risk of ovarian/breast cancers

Alza ovarian cancer drug recommended for EU approval


June 2000

FDA approves new Taxol regimen for treating ovarian cancer


May 2000

Bleomycin, etoposide, and cisplatin an effective regimen for ovarian tumors

Doxorubicin better tolerated by ovarian cancer patients than topotecan

NICE recommends use of taxanes for treatment of ovarian cancer

new gold standard for advanced ovarian cancer

BRCA mutations associated with longer survival in ovarian cancer patients


April 2000

Identifiable factors account for half of ovarian cancers

AltaRex receives patent allowance for ovarian cancer treatment

Copolymer-bound doxorubicin shows potent activity in ovarian cancer model

Conservative surgery for borderline ovarian tumors confirmed to preserve fertility


March 2000

Removal of benign ovarian cysts does not lower risk of death from ovarian cancer

OCs may protect against ovarian cancer in part via direct antiandrogen effects


February 2000

Deep venous thrombosis prophylaxis cost-effective for gynecologic cancer surgery patients

Low-dose topotecan effective, less toxic in refractory ovarian cancer

Fertility-sparing surgery effective in patients with stage I ovarian cancer


January 2000

Cisplatin and paclitaxel for ovarian cancer effective, less toxic than cisplatin alone


December 1999

Ovarian tumor index predicts malignancy

Novel cadherin antagonist kills ovarian tumor cells in mice


November 1999

Stage III ovarian cancer survival better in women treated by gynecologic oncologists


October 1999

National Cancer Institute to provide $29 million for ovarian cancer research

No association detected between fertility drugs and ovarian cancer


September 1999

Details on first ovarian tissue autotransplantation reported

Photoimmunotherapy enhances cytotoxicity of cisplatin in human ovarian cancer cells ex vivo

New treatment approach spares fertility in most women with ovarian germ cell tumors


August 1999

Atairgin, Northwestern University to develop ovarian cancer test

Women with ovarian, endometrial cancers at increased risk of colorectal cancer


July 1999

Lactose absorption linked to ovarian cancer


June 1999

FDA expands doxorubicin indication to include refractory ovarian cancer

Randomized trial of gene therapy for ovarian cancer to begin at UCLA

Epithelial ovarian cancer in women of reproductive age compared with same cancer in postmenopausal women

Minilaparotomy feasible for outpatient management of ovarian cysts

FDA advisory committee backs approval of doxorubicin for ovarian cancer


May 1999

OC use recommended for women with family history of ovarian cancer


April 1999

Fertility drugs do not increase risk of breast, ovarian cancer

FDA will expedite review of Doxil for ovarian cancer

Ovarian cancer screening at greater than 1-year intervals unlikely to detect early-stage disease

Ovarian cancer screening may improve survival rates


March 1999

Adjuvant chemo prevents relapse of stage I testicular nonseminomatous germ cell tumor

Breast cancer diagnosis before age 50 increases risk of later ovarian cancer diagnosis

Hereditary ovarian cancers rare in women of childbearing age

Combination therapy revisited for advanced ovarian cancer


February 1999

Tamoxifen linked to ovarian cyst formation in premenopausal breast cancer patients

BRCA1/2 gene mutations unrelated to survival in women with breast or ovarian cancers


January 1999

Tumor stage influences recurrence risk in platinum-treated ovarian cancer

Age, race, geography influence risk of ovarian cancer mortality in US

Maternally-imprinted tumor suppressor gene in breast and ovarian cancers identified