Chemotherapy

Why I Chose Breast Oncology
Carla Fisher, MD Like many others, my path into the field of oncology was not a direct one. After making the decision to enter medical school, I chose to pursue a career in surgery followed by a specialization in breast oncology. As I look back, each choice was made for different reasons at different times and ultimately I am so happy with the

Randomized Trial of High-dose Chemotherapy and Blood Cell Autografts for High-Risk Primary Breast Carcinoma
Reviewers: Li Liu, MD Source: Journal of the National Cancer Institute, Volume 92, No.3 (February):225-233, 2000BackgroundIn patients with high-risk breast carcinoma some studies have suggested that high-dose chemotherapy (HDC) and autologous hematopoietic stem cell support (AHSCS) improved tumor response rates compared with conventional-dose

Increased Risk of Acute Leukemia After Adjuvant Chemotherapy for Breast Cancer: A Population-Based Study
Reviewers: Li Liu, MD Source: Journal of Clinical Oncology, Volume 18:2836-2842, (August) 2000Précis: Adjuvant treatment for breast cancer increased leukemia riskIntroductionSince the mid-1970s, adjuvant chemotherapy has been widely used to treat breast cancer with regional lymph-node involvement. More recently, systemic drug therapy has

Preoperative Chemotherapy for Breast Cancer
Reviewers: John Han-Chih Chang, MD Source: Journal of Clinical Oncology Jul 1997; Volume 15: pages 2483 - 93This article details the preliminary data from the National Surgical Adjuvant Breast and Bowel Project trial B-18. This study was designed to evaluate the efficacy of neoadjuvant or (preoperative) chemotherapy in affording breast cancer

Prospective Randomized Trial of Docetaxel Versus Mitomycin Plus Vinblastine in Patients With Metastatic Breast Cancer Progressing Despite Previous Anthracycline-Containing Chemotherapy
Reviewers: Li Liu, MD Source: Journal of Clinical Oncology, Vol 17, Issue 5 (May), 1999: 1413-1424IntroductionIt is clear that chemotherapy provides clinical benefit to many women with metastatic breast cancer (J Clin Oncol. 1996 Aug;14(8):2197-205). However, metastatic breast cancer remains essentially incurable and almost all women with such