Surgical Oncology

Mastectomy

Long-Term Results of a Randomized Trial Comparing Breast-Conserving Therapy With Mastectomy: European Organization for Research and Treatment of Cancer 10801 Trial Reviewers: Li Liu, MD Source: Journal of the National Cancer Institute, Volume 92(14):1143-1150, (July) 2000Précis: Survival is similar after mastectomy, breast-conserving therapy for stage II tumorsIntroductionIt has been well established that either radical mastectomy or breast-conserving therapy results in the same long-term survival
Second Malignancies after Treatment of Early-Stage Breast Cancer: Lumpectomy and Radiation Therapy Versus Mastectomy Reviewers: Li Liu, M.D Source: Journal of Clinical Oncology, Volume 18 (12), 2406-2412 (June) 2000Précis: Radiation for breast cancer is not associated with greater risk of second malignancy.IntroductionAlmost all types of cancer can be caused by exposure to ionizing radiation with exception of chronic lymphocytic leukemia. Recent studies
Prognostic Value of p53 for Local Failure in Mastectomy-Treated Breast Cancer Patients Reviewers: Li Liu, MD Source: Journal of Clinical Oncology, Vol. 18, No 9, 1906-1913, (May) 2000IntroductionRandomized clinical trials have established that radiation therapy improves the local regional control and survival in selected breast cancer patients treated with mastectomy. However, only about 50% of patients will benefit from
Twenty-Year Follow-up of a Randomized Trial Comparing Total Mastectomy, Lumpectomy, and Lumpectomy Plus Irradiation for the Treatment of Invasive Breast Cancer Authors: Bernard Fisher, M.D., Stewart Anderson, Ph.D., John Bryant, Ph.D., et al. Source: N Engl J Med 2002, 347:1233-1241 Background The National Surgical Adjuvant Breast and Bowel Project (NSABP) protocol B-04 showed that over 25 years of follow-up there was no significant difference in survival between women treated with a radical
Efficacy of Bilateral Prophylactic Mastectomy in Women with a Family History of Breast Cancer Reviewers: Kenneth Blank, MD Source: The New England Journal of Medicine, January 14, 1999, Volume 340, Number 2BackgroundThe treatment of breast cancer has changed dramatically over the past two decades. Advances have included the recognition that breast conserving surgery when combined with radiotherapy offers similar survival compared to
Effect of Nancy Reagan's Mastectomy on Choice of Surgery for Breast Cancer by US Women Reviewers: John Han-Chih Chang, MD and Kenneth Blank, MD Source: Journal of the American Medical Association 1998; Volume 279: pages 762 - 766.BackgroundCancer treatment can take on various forms. It can include surgery, radiation therapy or chemotherapy. Recommendations on what is required to treat the certain cancer is influenced by extent of
Extracapsular Axillary Nodal Extension (ECE) in Breast Cancer: Patterns of Recurrence, Arm Edema, and Survival after Mastectomy with and Without Irradiation Presenter: Robert Kuske, MD Affiliation: Ochsner Clinic/Tulane University School of Medicine, New Orleans, LA Background:The prognostic implications of extracapsular extension (ECE) in breast cancer with axillary lymph node (ALN) disease is debatable. It has not been conclusively demonstrated that having ECE in positive ALNs is an indication
Second Malignancies after Treatment of Early Stage Breast Cancer with Lumpectomy and Radiation or Mastectomy without Radiation Presenter: E. Obedian Affiliation: Yale University School of Medicine Summary:Multiple studies have demonstrated the clinical efficacy of breast conserving therapy (BCT) for early stage breast cancer. Despite decades of experience, however, there are limited data regarding the safety of this treatment, specificially the risk of second
Eighteen-Year Results in the Treatment of Early-Stage Breast Cancer With Breast Conservation Versus Mastectomy Presenter: Matthew PoggiPresenter's Affiliation: Radiation Oncology Branch, NCI, Bethesda, MDType of Session: ScientificBackground Several randomized clinical trials comparing conservative surgery followed by whole breast irradiation to mastectomy for patients with early stage breast cancer have reported long-term outcomes. These studies include
The 2006 Worldwide Overview of the Effects of Local Treatments for Early Breast Cancer On Long-term Outcome? "Meta-analysis of the Randomized Trials of Radiotherapy After Mastectomy With Axillary Clearance" Presenter: Paul McGale, PhDPresenter's Affiliation: Clinical Trial Service Unit, United KingdomType of Session: PlenaryBackground Randomized trials have shown that post-mastectomy radiation therapy ( PMRT ) confers both a local control and survival benefit in certain patient populations. It is generally accepted that patients with 4 or
The 2006 Worldwide Overview of the Effects of Local Treatments for Early Breast Cancer On Long-term Outcome? "Meta-analysis of the Randomized Trials of Radiotherapy After Mastectomy With Axillary Clearance" The 2006 Worldwide Overview of the Effects of Local Treatments for Early Breast Cancer On Long-term Outcome? "Meta-analysis of the Randomized Trials of Radiotherapy After Mastectomy With Axillary Clearance" It is well understood that radiation therapy after mastectomy ( PMRT ) improves survival and decreases recurrence rates in women
Chest Wall Radiation Alone for Breast Cancer Patients With 1-3 Positive Lymph Nodes Treated by Mastectomy Presenter: Shannon M. MacDonald, MDPresenter's Affiliation: Massachusetts General HospitalType of Session: ScientificBackground Numerous studies have demonstrated that the administration of adjuvant comprehensive postmastectomy radiation, which includes radiation to the chest wall and supraclavicular region, reduces locoregional recurrences
Cardiac Toxicity is Not Increased 25 Years After Treatment of Early Stage Breast Carcinoma With Mastectomy or Breast Conservation Therapy From the National Cancer Institute Randomized Trial Abstract # 87 Presenting Author: Charles B. Simone, II, MD Presenting Author's Affiliation: Hospital of the University of Pennsylvania, Department of Radiation Oncology, Philadelphia, PA Background The current options for the treatment of early-stage breast cancer are modified radical mastectomy or breast-conserving surgery plus
Finding and Fitting a Breast Form: Tips for Breast Cancer Survivors Women with breast cancer face several cosmetic changes that may affect their body image and quality of life, including the loss of one or both breasts. In order to feel better about themselves and their bodies, some women may choose to be fitted with a breast prosthesis. Breast prostheses are breast forms that are put inside a bra to make your